famciclovir104227-87-4
3 Inquiries
104227-87-4
pharmaceutical grade
99%
1
Ipure
25kg/Cardboard Drum
2026-09-27
pharmaceutical intermediates,chemical
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceOff-White PowderChEBI: 2-Amino-9H-purine in which the hydrogen at position 9 is substituted by a 4-acetoxy-3-(acetoxymethyl)but-1-yl group. A prodrug of the antiviral penciclovir, it is used for the treatment of acute herpes zoster (shingles), for the treatmen or suppression of recurrent genital herpes in immunocompetent patients and for the treatment of recurrent mucocutaneous herpes simplex infections in HIV infected patients.Famciclovir, an effective oral prodrug of the antiviral penciclov
Solid
Famciclovir is 2-Amino-9H-purine in which the hydrogen at position 9 is substituted by a 4-acetoxy-3-(acetoxymethyl)but-1-yl group. A prodrug of the antiviral penciclovir, it is used for the treatment of acute herpes zoster (shingles), for the treatment or suppression of recurrent genital herpes in immunocompetent patients and for the treatment of recurrent mucocutaneous herpes simplex infections in HIV infected patients. It has a role as a prodrug and an antiviral drug. It is a member of 2-aminopurines and an acetate ester.|Famciclovir, marketed as Famvir by Novartis, is a guanine analogue used to treat herpes virus infections. It is most commonly used to treat herpes zoster (shingles). Famciclovir is a prodrug of penciclovir with higher oral bioavailability.|Famciclovir is a Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor. The mechanism of action of famciclovir is as a DNA Polymerase Inhibitor, and DNA Polymerase Inhibitor.|Famciclovir is a nucleoside analogue and antiviral agent used in therapy of herpes zoster and simplex virus infections. Famciclovir is associated with a low rate of mild-to-moderate serum ALT elevations during therapy, but has not been associated with instances of clinically apparent liver injury.|Famciclovir is a diacetyl 6-deoxy prodrug analog of the antiviral agent penciclovir. Orally administered, famciclovir in vivo is converted to penciclovir triphosphate, which is active against the Herpes viruses, including herpes simplex 1 and 2 and varicella-zoster. This agent inhibits the replication of viral DNA by interfering competitively with DNA polymerase. (NCI04)|An aminopurine derivative and prodrug of penciclovir which is a competitive inhibitor of herpes simplex 2 DNA polymerase. It is used to treat HERPES SIMPLEX VIRUS INFECTION.Basic Info-
Product Name:
Famciclovir
Other Name:1,3-Propanediol,2-[2-(2-amino-9H-purin-9-yl)ethyl]-,1,3-diacetate;1,3-Propanediol,2-[2-(2-amino-9H-purin-9-yl)ethyl]-,diacetate (ester);Famciclovir;BRL 42810;Famvir;FCV;9-[4-Acetoxy-3-(acetoxymethyl)butyl]-2-aminopurine;9-[4-Acetoxy-3-(acetoxymethyl)but-1-yl]-2-aminopurine;Famcyclovir;Famcivir;Famtrex;Fanxiluowei;[2-(Acetyloxymethyl)-4-(2-aminopurin-9-yl)butyl] acetate;2-[(Acetyloxy)methyl]-4-(2-amino-9H-purin-9-yl)butyl acetate
CAS No.:104227-87-4
Molecular Formula:C14H19N5O4
InChIKeys:InChIKey=GGXKWVWZWMLJEH-UHFFFAOYSA-N
Molecular Weight:321.33
Exact Mass:321.33
EC Number:1312995-182-4
UNII:QIC03ANI02
NSC Number:758921
DSSTox ID:DTXSID0023038
NCI Thesaurus Code:C29044
Color/Form:White shiny plates from ethyl acetate-hexane
ATC Code:J - Antiinfectives for systemic use|S - Sensory organs
HScode:29335990
Categories:
Characteristics-
PSA:
122
XLogP3:0
Appearance:Solid
Density:1.40±0.1 g/cm3(Predicted)
Melting Point:102-104 °C
Boiling Point:550.2±60.0 °C(Predicted)
Flash Point:286.6±32.9 °C
Refractive Index:1.628
Water Solubility:DMSO: ≥10mg/mL
Storage Conditions:-20°C Freezer
Vapor Pressure:1.13X10-9 mm Hg at 25 deg C (est)
Henrys Law Constant:Henry's Law constant = 9.35X10-14 atm-cu m/mol at 25 °C (est)
Dissociation Constants:pKa1 = 2.91; pKa2 = 3.83 (est)
Collision Cross Section:168.4 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Hazard IdentificationClassification of the substance or mixture
Eye irritation, Category 2
Reproductive toxicity, Category 1B
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Danger
Hazard statement(s) H319 Causes serious eye irritation
H360 May damage fertility or the unborn child
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P203 Obtain, read and follow all safety instructions before use.
Response P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P318 IF exposed or concerned, get medical advice.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
pharmaceutical intermediates,chemical
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Location:
Company Office Address: Room 1508, 15/F, Yate Centre Office Tower 2, 625 Nathan Road, Mong Kok, Hong Kong
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Payment Terms:
TT against copy of documents,D/P,L/C,O/A,100% TT in advance
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Average lead Time:
10
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Total Annual Revenue:
$1 million-$2.5 million
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Total Employees:
11-50
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Year of Establishment:
2025
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Inquiry History3 Inquiries
Country Product Purchase Quantity Date Posted
Thailand
famciclovir
5 MG Aug 27, 2026
Turkey
famciclovir
2 KG Jan 22, 2025
Turkey
Famciclovir
1 KG Dec 25, 2023 Post an enquiry for this product