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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Lapatinib ditosylate monohydrate for Sale > Lapatinib Ditosylate CAS 388082-78-8 Dual EGFR/HER2 Tyrosine Kinase Inhibitor for Breast Cancer Research hfd
Lapatinib Ditosylate CAS 388082-78-8 Dual EGFR/HER2 Tyrosine Kinase Inhibitor for Breast Cancer Research  hfd buy - large image1
Lapatinib Ditosylate CAS 388082-78-8 Dual EGFR/HER2 Tyrosine Kinase Inhibitor for Breast Cancer Research  hfd buy - image1
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Lapatinib Ditosylate CAS 388082-78-8 Dual EGFR/HER2 Tyrosine Kinase Inhibitor for Breast Cancer Research  hfd buy - image4
Lapatinib Ditosylate CAS 388082-78-8 Dual EGFR/HER2 Tyrosine Kinase Inhibitor for Breast Cancer Research  hfd buy - image5
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Lapatinib Ditosylate CAS 388082-78-8 Dual EGFR/HER2 Tyrosine Kinase Inhibitor for Breast Cancer Research hfd

TDS 3 Inquiries

Unit Price:

$100-130/G FOB

Get Latest Price
CAS No.:

388082-78-8

Grade:

Reagent Grade

Content:

99%

Port:

qingdao

Brand:

//

Packaging:

5g, 25g, 100g, 500g

Price valid (until):

2026-09-27

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Medetomidine,Medetomidine hydrochloride,D-Lysergic Acid Methyl Ester,SR17018,Fluralaner,GS-441524

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

    —— Product Specification ——

    Parameter Specification Details
    Product Name Lapatinib Ditosylate Lapatinib Ditosylate Monohydrate; Tykerb; Tyverb
    CAS Number 388082-78-8 388082-78-8 
    Molecular Formula C₂₉H₂₆ClFN₄O₄S·2C₇H₈O₃S·H₂O
    Molecular Weight 943.47 g/mol
    Appearance White to off-white solid powder Visual inspection
    Purity ≥98.0% Determined by HPLC
    EGFR IC₅₀ 10.8 nM Potent EGFR inhibition 
    ErbB2/HER2 IC₅₀ 9.2 nM Potent HER2 inhibition 
    ErbB4 IC₅₀ 367 nM Weak inhibition 
    Solubility DMSO: ≥91 mg/mL (96.45 mM)
    Storage Powder: -20°C for 3 years; In solvent: -80°C for 1 year Sealed containers, protect from light 
    Packaging 100mg, 500mg, 1g, 5g, 25g Amber glass vials
    Application Research use only Oncology research, kinase inhibition studies


    —— Product Detail ——

    Product Overview

    • Lapatinib Ditosylate (CAS 388082-78-8) is the ditosylate salt monohydrate form of lapatinib, an orally active, reversible dual tyrosine kinase inhibitor that targets both EGFR (ErbB-1) and HER2 (ErbB-2) . It is marketed under the brand names Tykerb and Tyverb for the treatment of HER2-positive advanced or metastatic breast cancer


    Packaging & Shipping

                  • Research quantities: 5mg, 10mg, 25mg amber glass vials

                  • Bulk quantities: 50mg, 100mg amber glass bottles

                  • Custom packaging available upon request

                  • Not classified as hazardous material for transport under normal conditions

                  • Product for research and analytical use only; not for human therapeutic use

    Shop CAS 18048-64-1 Eltrombopag Intermediate for Pharmaceutical Research  kr-Detailed Image 1

    Company profile ——


     Shop CAS 1231930-42-9 Abemaciclib Intermediate for Pharma researech use KR-Detailed Image 1

    Jinan Topfull Chemical Co., Ltd. is an international company rooted in China, specializing in the export of chemical products.

    Our company is committed to making every effort to provide ideal chemical products to potential customers worldwide, including but not limited to: organic/inorganic reagents, biological reagents, plant extracts, pharmaceutical intermediates, active pharmaceutical ingredients (APIs), reference standards, reference substances, peptides, and more. Meanwhile, we have established long-term and stable cooperative relationships with university laboratories and off-campus research institutions, enabling us to offer tailored product services based on customers' actual needs.

    We currently support customized services for most product categories, with supply quantities ranging from milligram (mg), gram (g) to kilogram (kg) levels, as well as wholesale. Product purity covers the full spectrum from 90% to 99.9%, providing customers with one-stop convenient services.

    To date, our products have been exported to developed countries such as the United States, Australia, Canada, Mexico, as well as EU member states including France, Germany, and many other countries and regions such as Nigeria, Ghana, Southeast Asia, and other parts of Asia. Our product quality and services have consistently received high praise.

    Looking ahead, our company will continue to serve as a bridge connecting China and the world, delivering high-quality products and services to global customers.

     

    Shop CAS 1231930-42-9 Abemaciclib Intermediate for Pharma researech use KR-Detailed Image 2

    Shop CAS 1231930-42-9 Abemaciclib Intermediate for Pharma researech use KR-Detailed Image 3

    —— Q&A ——

    Q1: How to confirm the product quality before placing orders?
    A: By sending you available samples. Or if you have special requirements for the goods, we can prepare samples according to your requirements for confirmation.

    Q2: Can you supply free samples?
    A: Yes, we can provide a free sample, but the shipping cost will be paid by the customers. You can either pay the shipping cost or arrange a courier to collect the samples.

    Q3: How do you treat quality complaints?
    A: All our products are strictly tested by our QC and confirmed by QA; unqualified material will not be released to customers. If any quality problem is confirmed to be caused by us, we will replace the goods or refund your payment immediately.

    Q4: What is your MOQ? Is there a discount?
    A: For highvalue products, our MOQ starts from 1g and generally starts from 10g. For other lowprice products, our MOQ starts from 100g and 1kg.
    Q: Is there a discount?
    A: Yes, for larger quantities, we always support with better prices.

    Q5: How to start orders or make payments?
    A: You can send us your Purchase Order (if your company has one), or just send a simple confirmation by email or via Trade Manager. We will then send you a Proforma Invoice with our bank details for your confirmation, and you can make payment accordingly. If you have other preferred payment methods, we are open to discussion and negotiation.



    ECHEMI Editorial Reference
    Lapatinib ditosylate monohydrate (GW572016 ditosylate monohydrate) is a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively[1].

    Certificates
    • Lapatinib Ditosylate CAS 388082-78-8 Dual EGFR/HER2 Tyrosine Kinase Inhibitor for Breast Cancer Research  hfd Certificates 1 TDS

    Basic Info
    Product Name:

    Lapatinib ditosylate monohydrate

    Other Name:

    4-Quinazolinamine,N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-,4-methylbenzenesulfonate,hydrate (1:2:1);4-Quinazolinamine,N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-,bis(4-methylbenzenesulfonate),monohydrate;Lapatinib ditosylate monohydrate

    CAS No.:

    388082-78-8

    Molecular Formula:

    C29H26ClFN4O4S.2C7H8O3S.H2O

    InChIKeys:

    InChIKey=DFHHLTRPIUJKPY-UHFFFAOYSA-N

    Molecular Weight:

    943.476

    Exact Mass:

    942.184143

    Characteristics
    PSA:

    249.46000

    XLogP3:

    12.26450

    Appearance:

    colourless to light-yellow crystal

    Density:

    1.403 g/mL (20.84 °C)

    Melting Point:

    237 - 239 °C

    Boiling Point:

    750.7ºC at 760 mmHg

    Flash Point:

    68 °F

    Refractive Index:

    n20/D 1.5520(lit.)

    Hazard Identification

    Classification of the substance or mixture

    Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 4

    GHS label elements, including precautionary statements

    Pictogram(s) No symbol.
    Signal word

    No signal word

    Hazard statement(s)

    H413 May cause long lasting harmful effects to aquatic life

    Precautionary statement(s)
    Prevention

    P273 Avoid release to the environment.

    Response

    none

    Storage

    none

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Medetomidine,Medetomidine hydrochloride,D-Lysergic Acid Methyl Ester,SR17018,Fluralaner,GS-441524

    Location:

    RONGSHENG BEIYUANDAJIE 9, LICHENG DISTRICT,JINAN, SHANDONG CHINA

    Payment Terms:

    TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    7

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    11-50

    Year of Establishment:

    2022

    Jinan Topfull Chemical Co., Ltd. is a global chemical Industrial and focuses on advanced chemical technology. Specialized in Cosmetic materials, water treatment, fine chemicals and so on. We are looking forward to working together with the people of all circles at home and abroad to seek common development!
  • Inquiry History
    3 Inquiries
    Country Product Purchase Quantity Date Posted
    United Arab Emirates

    Lapatinib Ditosylate Monohydrate

    25 KG Jan 28, 2026
    Pakistan

    LAPATINIB DITOSYLATE MONOHYDRATE

    25.00 KG Dec 31, 2024
    United Arab Emirates

    Lapatinib ditosylate monohydrate

    10.00 KG Jul 23, 2024
    Post an enquiry for this product
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