Methyl trans-ferulate 98% Purity Phenolic Acid Ester Standard CAS 22329-76-6 Research Grade Reference Standard

Product Overview

Methyl trans-ferulate is the methyl ester derivative of ferulic acid, a naturally occurring phenolic acid widely distributed in the plant kingdom. It is found in various medicinal herbs and serves as an important reference standard for the quantification of ferulic acid derivatives in botanical products.

With the molecular formula C₁₁H₁₂O₄ and a molecular weight of 208.21 g/mol, this compound appears as a white to off-white powder. It is soluble in methanol, ethanol, and DMSO. The product is supplied at ≥98% purity as determined by HPLC analysis.

Synthetic Process

Methyl trans-ferulate is typically synthesized via esterification of ferulic acid with methanol:

1. Esterification: Ferulic acid is refluxed with methanol in the presence of an acid catalyst.

2. Work-up: The reaction mixture is neutralized and extracted with organic solvent.

3. Purification: The crude ester is purified by recrystallization or column chromatography.

4. Identity Confirmation: Structure is confirmed by NMR and mass spectrometry.

Mechanism of Action & Applications

This compound is primarily used as:

• Reference Standard: For the quantification of ferulic acid esters in traditional Chinese medicines and herbal supplements.

• Method Validation: Used in HPLC method development and validation.

• Pharmacological Research: Serves as a standard for studying the metabolism and bioavailability of ferulic acid derivatives.

• Natural Product Chemistry: Used as a reference for phenolic compound identification.

Quality Specifications

• Purity: ≥98.0% determined by HPLC.

• Identity: Confirmed by NMR and mass spectrometry.

• Loss on Drying: ≤1.0%.

• Each batch is accompanied by a comprehensive COA.

• Stable for 24 months when stored at 2-8°C in sealed containers, protected from light.

Packaging & Storage

• Standard packaging: 2mg, 5mg, 10mg amber glass vials.

• Store at 2-8°C, protected from light and moisture.

Jinan Topfull Chemical Co., Ltd. is an international company rooted in China, specializing in the export of chemical products.

Our company is committed to making every effort to provide ideal chemical products to potential customers worldwide, including but not limited to: organic/inorganic reagents, biological reagents, plant extracts, pharmaceutical intermediates, active pharmaceutical ingredients (APIs), reference standards, reference substances, peptides, and more. Meanwhile, we have established long-term and stable cooperative relationships with university laboratories and off-campus research institutions, enabling us to offer tailored product services based on customers' actual needs.

We currently support customized services for most product categories, with supply quantities ranging from milligram (mg), gram (g) to kilogram (kg) levels, as well as wholesale. Product purity covers the full spectrum from 90% to 99.9%, providing customers with one-stop convenient services.

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