L-Methionine

l-Methionine

L-Methionine;Methionine,L-;Cymethion;Methionine;Butanoic acid,2-amino-4-(methylthio)-,(S)-;2-Amino-4-(methylthio)butyric acid;S-Methionine;α-Amino-γ-methylmercaptobutyric acid;γ-Methylthio-α-aminobutyric acid;(S)-2-Amino-4-(methylthio)butanoic acid;l-Methionine;L-α-Amino-γ-methylthiobutyric acid;L-Homocysteine,S-methyl-;h-Met-oh;Acimethin;NSC 22946;S-Methyl-L-homocysteine;Secretory peptide (human clone HTXDU73);Methiorep;Meth-o-Tas;(2S)-2-Azaniumyl-4-methylsulfanylbutanoate;(2S)-2-Amino-4-(methylsulfanyl)butanoic acid;7005-18-7;24425-78-3;1437749-32-0;1437749-60-4;1437749-65-9;1437749-75-1;1437749-80-8;1437769-00-0;1437870-94-4;1437870-95-5;1437870-97-7;1437870-98-8;1437871-20-9;1463481-01-7;1463481-06-2;1463481-15-3;1463481-19-7;1463481-23-3;1463481-27-7;1463481-31-3;1463481-37-9;1463481-41-5;1463481-46-0;1463481-51-7;1463481-58-4;1463481-73-3;1463481-80-2;1463481-89-1;1463610-75-4;1463610-76-5;1466415-57-5

63-68-3

C5H11NO2S

InChIKey=FFEARJCKVFRZRR-BYPYZUCNSA-N

149.21100

149.21

200-562-9

AE28F7PNPL

760117

DTXSID5040548

C29600

Minute hexagonal plates from dilute alcohol|Colorless or white, lustrous plates or as white, crystalline powder

V - Various

2930400000

Bulk Drug Intermediates

88.62000

-1.9

Minute hexagonal plates from dilute alcohol. (NTP, 1992)

1.206 g/cm3

280-282 °C (decomp)

123-126 °C @ Press: 15 Torr

139.4ºC

1.531

H2O: soluble

Store at RT.

8.14X10-8 mm Hg at 25 deg C (est)

LD50 oral in rat: 36gm/kg

Specific optical rotation: 22.5 deg at 25 °C/D (1 N HCl)

Faint

Sulfurous

pH (1% aqueous solution) = 5.6-6.1

2.28(at 25 °C)

Henry's Law constant = 2.11X10-11 atm-cu m/mol at 25 °C (est)

2.28 (at 25 °C)|pKa = 2.28; pK2 = 9.21

133.65 Ų [M+H]+ [CCS Type: DT, Method: stepped-field]|152.05 Ų [M-H]- [CCS Type: DT, Method: stepped-field]|127 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine]|133.1 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|132 Ų [M-H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|134.08 Ų [M+H]+ [CCS Type: DT, Method: stepped-field]|140.5 Ų [M-H]-

Platelets from alcohol. mp 281 °C (decomposes), density 1.340; pKa1 = 2.28, pKa2 = 9.21; pH of 1% aqueous solution 5.6-6.1; Rf value 0.77. Solubility in water (g/L) at 0 °C: 18.18; at 25 °C: 33.81; at 50 °C: 60/.70; at 75 °C: 15.2 °C. Soluble in dilute acids, alkalies. Very slightly soluble in 95% alcohol. Insoluble in ether. /Methionine, DL-form/|UV: 1-65 (Organic Electronic Spectral Data, Phillips et al, John Wiley & Sons, New York) /Methionine (DL)/|Hydroxyl radical reaction rate constant = 5.13X10-11 cu cm/molec-sec at 25 °C (est)

Reacts with water, steam, and/or acids to produce toxic and flammable vapors of hydrogen sulfide (NTP, 1992). Water soluble (NTP, 1992). pH of 1% aqueous solution is 5.6-6.0.

Sulfides, Organic

An organosulfide and amine derivative, carboxylic acid. Look at Reactive Groups 20 (organosulfides), 7 (amines), and 3 (carboxylic acids) may give indications about reactive tendencies. It is an amino acid essential in human nutrition.