DOXOFYLLINE
3 Inquiries
69975-86-6
99%
ShangHai
1kg
2026-10-01
HARD FAT
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceDoxofylline is an antagonist of adenosine A1 receptor which also inhibits phosphodiesterase IV.
Doxofylline is an oxopurine that is a derivative of xanthine, methylated at N-1 and N-3 and carrying a 1,3-dioxolan-2-ylmethyl group at N-7, used in the treatment of asthma. It has a role as a bronchodilator agent, an antitussive and an anti-asthmatic drug. It derives from a 7H-xanthine.|Doxofylline is a methylxanthine derivative with the presence of a dioxolane group in position 7. As a drug used in the treatment of asthma, doxofylline has shown similar efficacy to theophylline but with significantly fewer side effects in animal and human studies. In contrast with other xanthine derivatives, doxofylline does not significantly bind to adenosine alpha-1 or alpha-2 receptors and lacks stimulating effects. Decreased affinity for adenosine receptors may account for the better safety profile of doxofylline compared to theophylline. Unlike theophylline, doxofylline does not affect calcium influx and does not antagonize the actions of calcium channel blockers which could explain reduced cardiac adverse reactions associated with the drug. The anti-asthmatic effects of doxophylline are mediated by other mechanisms, primarily through inhibiting the activities of the phosphodiesterase (PDE) enzyme.Basic Info-
Product Name:
Doxofylline
Other Name:1H-Purine-2,6-dione,7-(1,3-dioxolan-2-ylmethyl)-3,7-dihydro-1,3-dimethyl-;Theophylline,7-(1,3-dioxolan-2-ylmethyl)-;7-(1,3-Dioxolan-2-ylmethyl)-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione;2-(7′-Theophyllinemethyl)-1,3-dioxolane;ABC 1213;Dioxyfilline;Doxophylline;Doxofylline;Ansimar;Maxivent;ABC 12/3;Ventax;Synasma
CAS No.:69975-86-6
Molecular Formula:C11H14N4O4
InChIKeys:InChIKey=HWXIGFIVGWUZAO-UHFFFAOYSA-N
Molecular Weight:266.25
Exact Mass:266.25
EC Number:274-239-6
UNII:MPM23GMO7Z
NSC Number:759645
DSSTox ID:DTXSID7022968
ATC Code:R - Respiratory system
HScode:29399990
Categories:
Characteristics-
PSA:
76.9
XLogP3:-0.70
Density:1.6±0.1 g/cm3
Melting Point:144-145.5 °C
Boiling Point:505.2±53.0 °C at 760 mmHg
Flash Point:259.3±30.9 °C
Refractive Index:1.700
Water Solubility:H2O: soluble
Toxicity:LD50 in mice (mg/kg): 841 orally; 215.6 i.v.; in rats: 1022.4 orally, 445 i.p. (Franzone)
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
Skin irritation, Category 2
Eye irritation, Category 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
HARD FAT
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Location:
BUILDING 4,NO.571, STR.19,BAIYANG DISTRICT, HANGZHOU,CHINA
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Payment Terms:
TT against copy of documents,TT against B/L draft before shipment,100% TT in advance
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Total Annual Revenue:
Less than $1 million
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Total Employees:
5-10
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Year of Establishment:
2025
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Inquiry History3 Inquiries
Country Product Purchase Quantity Date Posted 
Bangladesh
Doxophylline
1 KG Mar 4, 2026
Bangladesh
Doxophylline
100 KG Mar 4, 2026 
Pakistan
Doxofylline Sodium
150 KG Jul 16, 2025 Post an enquiry for this product
