F410 | Foxo4-DRI | 99% White powder High Quality semaglutide weight CAS NO. 2460055-10-9
TDS 28 Inquiries
2460055-10-9
High Purity Grade
99%
Shenzhen
Tong Peptides
10mg/vial, 10 vials/box
2027-03-20
retatrutide,TB-500,GHK-CU,peptide
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceFOXO4-DRI (Retro-Inverso) is a synthetic, slightly modified version of the standard FOXO4 protein. The modification prolongs half-life of the protein and allows it to interfere with normal FOXO4 function. FOXO4-DRI has been shown in research to prevent normal FOXO4 binding to p53, thereby allowing for elimination of senescent cells, improved organ function, and younger tissue “biological age.” FOXO4-DRI impacts insulin signaling, cell cycle regulation, and oxidative stress signaling pathways. FOXO4-DRI is a cell penetrating peptide shown to selectively induce apoptosis of senescent cells thereby reversing effects of aging in animal studies.CertificatesBasic Info
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Product Name:
FOXO4-DRI
Other Name:FOXO4-DRI;FOXO4 /FOXO4-DRI;FOX04-DRI (D-Retro-Inverso);Fox4-dri
CAS No.:2460055-10-9
Molecular Weight:0
Color/Form:White to off-white
Categories:
Research-
Class:
GLP-1R agonist
Status:FDA-approved (Ozempic / Wegovy / Rybelsus)
Mechanism:Long-acting, selective glucagon-like peptide-1 (GLP-1) receptor agonist with 94% sequence homology to human GLP-1. Engineered for extended half-life (~1 week) via albumin binding (fatty acid acylation at Lys26) and resistance to DPP-4 degradation (Aib substitution at position 8). Promotes insulin secretion, inhibits glucagon release, delays gastric emptying, and reduces appetite via central nervous system GLP-1R activation.
Activity note:Potent, selective GLP-1R agonist. Reported binding affinity Ki = 0.38 ± 0.06 nM. Semaglutide is a human GLP-1 analog with structural modifications for albumin binding (C18 fatty diacid at Lys26) and enzymatic stability (Aib8 substitution).
Source:Lau J, et al. J Med Chem. 2015;58(18):7370-7380. Wilding JPH, et al. N Engl J Med. 2021;384(11):989-1002.DOI
Clinical Development:FDA:Ozempic, Wegovy, Rybelsus (approved 2017-12-05)
References-
ChEMBL:DrugBank:KEGG DRUG:PubChem:Literature:
NEJM: Wilding et al. (2021) — STEP-1; NEJM: Marso et al. (2016) — SUSTAIN-6; J Med Chem: Lau et al. (2015) — Discovery of Semaglutide; FDA: Ozempic (NDA 209637)
Disclaimer:Semaglutide is approved as a prescription medicine (Ozempic, Wegovy, Rybelsus) in certain jurisdictions. This listing is for industrial and laboratory research use only. Research-chemical listings on B2B marketplaces are not interchangeable with approved medicines. Confirm CAS, specification, and regulatory pathway with the seller. It is not medical advice, a clinical recommendation, or an approved therapy description.
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Seller Information
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Business Type:
Manufactory
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Main Products:
retatrutide,TB-500,GHK-CU,peptide
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Location:
1-1, Kailuo Road, Taojia Town, Jiulongpo District, Chongqing
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Payment Terms:
TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance
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Total Annual Revenue:
$10 million-$25 million
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Total Employees:
501-1000
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Year of Establishment:
2023
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Inquiry History28 Inquiries
Country Product Purchase Quantity Date Posted
United States
FOXO4-DRI
1 G Dec 3, 2023
Norway
FOXO4-DRI
200 MG Sep 3, 2026
United Kingdom
High purity foxo4
1 G May 31, 2026
United Kingdom
Foxo4-Dri
10 MG May 5, 2026
United States
Fox04-dri
100 MG Apr 28, 2026
Cyprus
Foxo4 dri
10 MT Apr 4, 2026
Cyprus
FOXO4-DRI
1 KG Feb 2, 2026
United States
FOX04-DRI
10 PCS Jan 12, 2026
United States
FOX04
10 PCS Jan 12, 2026
United States
Foxo4 Dri
40 MG Sep 15, 2025
United States
Fox04 dri
10 MT Jun 21, 2026
United States
FOX04-DRI powder
10 MT May 29, 2026
United States
fox04
1 G Apr 29, 2026
United States
FOXO4-DRI
1 KG Mar 23, 2026
United States
Foxo4-Dri
2 Nov 24, 2025
United States
FOXO4
10 PCS Nov 15, 2025
United States
Fox04
1 G Nov 10, 2025
United States
FOX04
10 G Oct 22, 2025
United States
FOXO4-DRI
5 PCS Oct 18, 2025
Russia
Foxo4dri
5 G Sep 11, 2025 Post an enquiry for this product
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