Ramelteon
196597-26-9
Pharma Grade
99%
DAHAI BIOCHEM
25kg/Cardboard Drum
2026-12-31
HARD FAT
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceThe selectivity of the resulting ramelteon for MT1 receptor iseight times more than that of MT2 receptor. Unlike melatonin,it is more effective in initiating sleep (MT1 activity)rather than to readjust the circadian rhythm (MT2 activity). Itappears to be distinctly more efficacious than melatonin butless efficacious than benzodiazepines as a hypnotic.Importantly, this drug has no addiction liability (it is not acontrolled substance). As a result, it has recently been approvedfor the treatment o
Solid
N-[2-[(8S)-2,6,7,8-tetrahydro-1H-cyclopenta[e]benzofuran-8-yl]ethyl]propanamide is a member of indanes.|Ramelteon is the first in a new class of sleep agents that selectively binds to the melatonin receptors in the suprachiasmatic nucleus (SCN). It is used for insomnia, particularly delayed sleep onset. Ramelteon has not been shown to produce dependence and has shown no potential for abuse.|Ramelteon is a Melatonin Receptor Agonist. The mechanism of action of ramelteon is as a Melatonin Receptor Agonist.|Ramelteon is a melatonin receptor agonist that is used for the treatment of insomnia. Ramelteon has not been implicated in causing serum enzyme elevations or clinically apparent liver injury.|Ramelteon is a synthetic melatonin analogue with hypnotic and circadian rhythm-modulating activities. Ramelteon binds to and activates melatonin receptors 1 and 2 in the suprachiasmatic nucleus (SCN) of the brain, thereby promoting the onset of sleep. Unlike the nonbenzodiazepine sedative hypnotics zolpidem and zaleplon, this agent does not activate GABA receptors and, so, produces no GABA receptor-mediated anxiolytic, myorelaxant, and amnesic effects.Basic Info-
Product Name:
Ramelteon
Other Name:Propanamide,N-[2-[(8S)-1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl]ethyl]-;Propanamide,N-[2-(1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethyl]-,(S)-;N-[2-[(8S)-1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl]ethyl]propanamide;TAK 375;Ramelteon;(S)-N-[2-(1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethyl]propionamide;Rozerem;(S)-N-[2-(1,6,7,8-Tetrahydro-2H-indeno-[5,4-b]furan-8-yl)ethyl]propionamide;Rozerm
CAS No.:196597-26-9
Molecular Formula:C16H21NO2
InChIKeys:InChIKey=YLXDSYKOBKBWJQ-LBPRGKRZSA-N
Molecular Weight:259.349
Exact Mass:259.34
EC Number:-0
UNII:901AS54I69
DSSTox ID:DTXSID6045951
NCI Thesaurus Code:C66504
Color/Form:Crystals from ethyl acetate
ATC Code:N - Nervous system
Categories:
Characteristics-
PSA:
38.3
XLogP3:2.7
Appearance:Solid
Density:1.119±0.06 g/cm3(Predicted)
Melting Point:113-115 °C @ Solvent: Ethyl acetate
Boiling Point:455.3±24.0 °C(Predicted)
Flash Point:2℃
Refractive Index:1.556
Water Solubility:1.64e-02 g/L
Vapor Pressure:7.4X10-8 mm Hg at 25 deg C (est)
Specific rotation:Specific optical rotation: -57.8 deg at 20 °C/D (concentration = 1.004 g/100 mL in chloroform)
Henrys Law Constant:Henry's Law constant = 8.62X10-11 atm-cu m/mol at 25 °C (est)
Experimental Properties:Hydroxyl radical reaction rate constant = 9.87X10-11 cu cm/molec-sec at 25 °C (est)
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H302 Harmful if swallowed
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
HARD FAT
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Location:
BUILDING 4,NO.571, STR.19,BAIYANG DISTRICT, HANGZHOU,CHINA
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Payment Terms:
TT against copy of documents,TT against B/L draft before shipment,100% TT in advance
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Total Annual Revenue:
Less than $1 million
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Total Employees:
5-10
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Year of Establishment:
2025
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Country Product Purchase Quantity Date Posted Post an enquiry for this product