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Ramelteon

Unit Price: Get Latest Price
CAS No.:

196597-26-9

Content:

99%

Packaging:

Bottle,barrel,cargo,container,etc.

Price valid (until):

2026-10-06

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals

  • Product Description

  • Seller Information

  • Description
    Keywords

    196597-26-9

    Ramelteon

    C16H21NO2

    Quick Details
    ProName:

    Ramelteon

    CasNo:

    196597-26-9

    Molecular Formula:

    C16H21NO2

    Appearance:

    powder, or liquid

    Application:

    Pharmaceuticals, intermediates, APIs, custom synthesis, chemicals

    DeliveryTime:

    5-7 Days

    PackAge:

    Bottle, barrel, cargo, container, etc.

    Port:

    Shanghai

    Purity:

    99

    Storage:

    Stored in room temperature, ventilated place

    Transportation:

    By air, ship, express, etc.

    LimitNum:

    0

    Grade:

    Industrial Grade

    Superiority

    Best Seller, High Quality, Competitive Price, Fast Delivery, Quick Response

    Details
    LEAPChem supplies high quality Pharmaceuticals, intermediates, APIs, custom synthesis, fine chemicals and other industrial chemicals
    ECHEMI Editorial Reference
    The selectivity of the resulting ramelteon for MT1 receptor iseight times more than that of MT2 receptor. Unlike melatonin,it is more effective in initiating sleep (MT1 activity)rather than to readjust the circadian rhythm (MT2 activity). Itappears to be distinctly more efficacious than melatonin butless efficacious than benzodiazepines as a hypnotic.Importantly, this drug has no addiction liability (it is not acontrolled substance). As a result, it has recently been approvedfor the treatment o
    Solid
    N-[2-[(8S)-2,6,7,8-tetrahydro-1H-cyclopenta[e]benzofuran-8-yl]ethyl]propanamide is a member of indanes.|Ramelteon is the first in a new class of sleep agents that selectively binds to the melatonin receptors in the suprachiasmatic nucleus (SCN). It is used for insomnia, particularly delayed sleep onset. Ramelteon has not been shown to produce dependence and has shown no potential for abuse.|Ramelteon is a Melatonin Receptor Agonist. The mechanism of action of ramelteon is as a Melatonin Receptor Agonist.|Ramelteon is a melatonin receptor agonist that is used for the treatment of insomnia. Ramelteon has not been implicated in causing serum enzyme elevations or clinically apparent liver injury.|Ramelteon is a synthetic melatonin analogue with hypnotic and circadian rhythm-modulating activities. Ramelteon binds to and activates melatonin receptors 1 and 2 in the suprachiasmatic nucleus (SCN) of the brain, thereby promoting the onset of sleep. Unlike the nonbenzodiazepine sedative hypnotics zolpidem and zaleplon, this agent does not activate GABA receptors and, so, produces no GABA receptor-mediated anxiolytic, myorelaxant, and amnesic effects.

    Basic Info
    Product Name:

    Ramelteon

    Other Name:

    Propanamide,N-[2-[(8S)-1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl]ethyl]-;Propanamide,N-[2-(1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethyl]-,(S)-;N-[2-[(8S)-1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl]ethyl]propanamide;TAK 375;Ramelteon;(S)-N-[2-(1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethyl]propionamide;Rozerem;(S)-N-[2-(1,6,7,8-Tetrahydro-2H-indeno-[5,4-b]furan-8-yl)ethyl]propionamide;Rozerm

    CAS No.:

    196597-26-9

    Molecular Formula:

    C16H21NO2

    InChIKeys:

    InChIKey=YLXDSYKOBKBWJQ-LBPRGKRZSA-N

    Molecular Weight:

    259.349

    Exact Mass:

    259.34

    EC Number:

    -0

    UNII:

    901AS54I69

    DSSTox ID:

    DTXSID6045951

    NCI Thesaurus Code:

    C66504

    Color/Form:

    Crystals from ethyl acetate

    ATC Code:

    N - Nervous system

    Categories:

    Standard

    Characteristics
    PSA:

    38.3

    XLogP3:

    2.7

    Appearance:

    Solid

    Density:

    1.119±0.06 g/cm3(Predicted)

    Melting Point:

    113-115 °C @ Solvent: Ethyl acetate

    Boiling Point:

    455.3±24.0 °C(Predicted)

    Flash Point:

    2℃

    Refractive Index:

    1.556

    Water Solubility:

    1.64e-02 g/L

    Vapor Pressure:

    7.4X10-8 mm Hg at 25 deg C (est)

    Specific rotation:

    Specific optical rotation: -57.8 deg at 20 °C/D (concentration = 1.004 g/100 mL in chloroform)

    Henrys Law Constant:

    Henry's Law constant = 8.62X10-11 atm-cu m/mol at 25 °C (est)

    Experimental Properties:

    Hydroxyl radical reaction rate constant = 9.87X10-11 cu cm/molec-sec at 25 °C (est)

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 4, Oral

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H302 Harmful if swallowed

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    Response

    P301+P317 IF SWALLOWED: Get medical help.

    P330 Rinse mouth.

    Storage

    none

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals

    Location:

    Room A, 23rd Floor, No. 609 Yan'an Road, Gongshu District, Hangzhou, Zhejiang

    Payment Terms:

    TT against copy of documents,D/P,L/C

    Average lead Time:

    5

    Total Annual Revenue:

    Above $100 million

    Year of Establishment:

    2020

    Certifications:

    ISO

    Company Profile

    LEAPChem is a specialized fine chemical supplier for research, development and production.

    LEAPChem provides nearly 200,000 rare and innovative chemical products to support the evolving needs of our customers in research & bulk manufacturing activities.

    As a highly customer-oriented enterprise, we are committed to providing high-quality customer services and products to our global customers in a cost-effective and efficient manner.

    Our client list includes many major pharmaceutical and science companies, universities, research institutions and chemical catalogue companies.


    Methodology: Sound & Stable; Active & Innovative.

    Attitude: Conscientious; Ingenious.

    Goals: Customer's Satisfaction


    We regard client's success as our success.

    At LEAPChem, we strive to be the preferred supplier for efficiency increasing and cost lowering in your Research & Production.

    To achieve this strategic vision, we always push ourselves to exceed our customer's requirement.  By focusing on the aim of 'Beyond Your Expectation', we continually expand our product lines, and enhance our systematic management and human resources.

    Welcome to contact us and we look forward to becoming your reliable and preferred partner.

    LEAPChem is a specialized fine chemical supplier for research, development and production.

    LEAPChem provides nearly 200,000 rare and innovative chemical products to support the evolving needs of our customers in research & bulk manufacturing activities.

    As a highly customer-oriented enterprise, we are committed to providing high-quality customer services and products to our global customers in a cost-effective and efficient manner.

    Our client list includes many major pharmaceutical and science companies, universities, research institutions and chemical catalogue companies.


    Methodology: Sound & Stable; Active & Innovative.

    Attitude: Conscientious; Ingenious.

    Goals: Customer's Satisfaction


    We regard client's success as our success.

    At LEAPChem, we strive to be the preferred supplier for efficiency increasing and cost lowering in your Research & Production.

    To achieve this strategic vision, we always push ourselves to exceed our customer's requirement.  By focusing on the aim of 'Beyond Your Expectation', we continually expand our product lines, and enhance our systematic management and human resources.

    Welcome to contact us and we look forward to becoming your reliable and preferred partner.

    ">Company Profile
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