folinic acid
5 Inquiries
58-05-9
Tech Grade
99%
DAHAI BIOCHEM
25kg/Drum
2026-12-31
HARD FAT
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceFolinic acid is an adjuvant used in cancer chemotherapy involving the drug methotrexate.Target: AntifolateFolinic acid is a 5-formyl derivative of tetrahydrofolic acid. It is readily converted to other reduced folic acid derivatives (e.g., tetrahydrofolate), and, thus, has vitamin activity that is equivalent to that of folic acid. Since it does not require the action of dihydrofolate reductase for its conversion, its function as a vitamin is unaffected by inhibition of this enzyme by dru
Folic acid is a water soluble vitamin found in many foods and particularly in leafy green vegetables that is essential for the critical biosynthetic pathways involving transfer of methyl groups to organic compounds. There is no evidence that folic acid, in physiologic or even super-physiologic, high doses, causes liver injury or jaundice.|The active metabolite of FOLIC ACID. Leucovorin is used principally as an antidote to FOLIC ACID ANTAGONISTS.
Folinic acid, chemical name N-[4-[(2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridyl) Methyl]amino]benzoyl-L-glutamic acid has been widely used in cancer combined chemotherapy. Folinic acid enters the human body through the ingestion and absorption pathway of folate. Folinic acid (calcium folinate) is a special form of reduced folic acid (folate).
Crystals. Sparingly soluble in water.
ChEBI: A formyltetrahydrofolic acid in which the formyl group is located at position 5.Basic Info-
Product Name:
Folinic acid
Other Name:5-formyl-5,6,7,8-tetrahydropteroyl-l-glutamicacid;leucoverin;5-formyl-5,6,7,8-tetrahydrofolate;5-formyltetrahydrofolate;5-formyltetrahydrofolic acid;N5-formyl-5,6,7,8-tetrahydrofolate;N5-formyl-tetrahydrofolate;2-[4-[(2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]aminopentanedioic acid
CAS No.:58-05-9
Molecular Formula:C20H23N7O7
InChIKeys:VVIAGPKUTFNRDU-ABLWVSNPSA-N
Molecular Weight:473.44
Exact Mass:473.44
EC Number:200-361-6
DSSTox ID:DTXSID3036999|DTXSID0048216
Color/Form:Pale Yellow to Light Yellow
Categories:
Characteristics-
PSA:
219.84000
XLogP3:1.15290
Density:1.4485 (rough estimate)
Melting Point:245°C (rough estimate)
Boiling Point:573.92°C (rough estimate)
Refractive Index:1.6800 (estimate)
Water Solubility:>1350g/L(25 ºC)
Vapor Pressure:2.3X10-21 mm Hg at 25 °C at 25 °C /Estimated/
Specific rotation:D20 +14.26° (c = 3.42 as anhydr Ca salt)
PH:pH of saturated solution in water = 2.8-3.0.
PKA:3.1, 4.8, 10.4(at 25℃)
Henrys Law Constant:Henry's Law constant = 4.4X10-27 atm-cu m/mole at 25 °C /Estimated/
Dissociation Constants:pKa1= 3.1; pKa2= 4.8; pKa3= 10.4
Experimental Properties:Crystals; decompose 240-250 °C; sparingly soluble in water. /dl-Folinic acid/|Hydroxyl radical reaction rate constant = 2.7X10-10 cu cm/molec-sec at 25 °C /Estimated/
Critical Temperature & Pressure:under inert gas (nitrogen or Argon) at 2–8 °C
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
HARD FAT
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Location:
BUILDING 4,NO.571, STR.19,BAIYANG DISTRICT, HANGZHOU,CHINA
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Payment Terms:
TT against copy of documents,TT against B/L draft before shipment,100% TT in advance
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Total Annual Revenue:
Less than $1 million
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Total Employees:
5-10
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Year of Establishment:
2025
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Inquiry History5 Inquiries
Country Product Purchase Quantity Date Posted 
Qatar
folinic acid
1 KG Feb 27, 2024 
Netherlands
Folinic acid
5 KG Mar 18, 2026 
United States
leucovorin
10 MG Sep 23, 2025 
Latvia
Folinic acid
1 20' Fcl Mar 4, 2026 
Australia
Leucovorin
1 KG Oct 21, 2025 Post an enquiry for this product