Folinic acid
5 Inquiries
58-05-9
99%
Bottle,barrel,cargo,container,etc.
2026-10-19
Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals
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Product Description
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Seller Information
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Inquiry History
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DescriptionKeywords
58-05-9
Folinic acid
C20H23N7O7
Quick DetailsProName:Folinic acid
CasNo:58-05-9
Molecular Formula:C20H23N7O7
Appearance:powder, or liquid
Application:Pharmaceuticals, intermediates, APIs, custom synthesis, chemicals
DeliveryTime:5-7 Days
PackAge:Bottle, barrel, cargo, container, etc.
Port:Shanghai
Purity:99
Storage:Stored in room temperature, ventilated place
Transportation:By air, ship, express, etc.
LimitNum:0
Grade:Industrial Grade
SuperiorityBest Seller, High Quality, Competitive Price, Fast Delivery, Quick Response
DetailsLEAPChem supplies high quality Pharmaceuticals, intermediates, APIs, custom synthesis, fine chemicals and other industrial chemicalsECHEMI Editorial ReferenceFolinic acid is an adjuvant used in cancer chemotherapy involving the drug methotrexate.Target: AntifolateFolinic acid is a 5-formyl derivative of tetrahydrofolic acid. It is readily converted to other reduced folic acid derivatives (e.g., tetrahydrofolate), and, thus, has vitamin activity that is equivalent to that of folic acid. Since it does not require the action of dihydrofolate reductase for its conversion, its function as a vitamin is unaffected by inhibition of this enzyme by dru
Folic acid is a water soluble vitamin found in many foods and particularly in leafy green vegetables that is essential for the critical biosynthetic pathways involving transfer of methyl groups to organic compounds. There is no evidence that folic acid, in physiologic or even super-physiologic, high doses, causes liver injury or jaundice.|The active metabolite of FOLIC ACID. Leucovorin is used principally as an antidote to FOLIC ACID ANTAGONISTS.
Folinic acid, chemical name N-[4-[(2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridyl) Methyl]amino]benzoyl-L-glutamic acid has been widely used in cancer combined chemotherapy. Folinic acid enters the human body through the ingestion and absorption pathway of folate. Folinic acid (calcium folinate) is a special form of reduced folic acid (folate).
Crystals. Sparingly soluble in water.
ChEBI: A formyltetrahydrofolic acid in which the formyl group is located at position 5.Basic Info-
Product Name:
Folinic acid
Other Name:5-formyl-5,6,7,8-tetrahydropteroyl-l-glutamicacid;leucoverin;5-formyl-5,6,7,8-tetrahydrofolate;5-formyltetrahydrofolate;5-formyltetrahydrofolic acid;N5-formyl-5,6,7,8-tetrahydrofolate;N5-formyl-tetrahydrofolate;2-[4-[(2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]aminopentanedioic acid
CAS No.:58-05-9
Molecular Formula:C20H23N7O7
InChIKeys:VVIAGPKUTFNRDU-ABLWVSNPSA-N
Molecular Weight:473.44
Exact Mass:473.44
EC Number:200-361-6
DSSTox ID:DTXSID3036999|DTXSID0048216
Color/Form:Pale Yellow to Light Yellow
Categories:
Characteristics-
PSA:
219.84000
XLogP3:1.15290
Density:1.4485 (rough estimate)
Melting Point:245°C (rough estimate)
Boiling Point:573.92°C (rough estimate)
Refractive Index:1.6800 (estimate)
Water Solubility:>1350g/L(25 ºC)
Vapor Pressure:2.3X10-21 mm Hg at 25 °C at 25 °C /Estimated/
Specific rotation:D20 +14.26° (c = 3.42 as anhydr Ca salt)
PH:pH of saturated solution in water = 2.8-3.0.
PKA:3.1, 4.8, 10.4(at 25℃)
Henrys Law Constant:Henry's Law constant = 4.4X10-27 atm-cu m/mole at 25 °C /Estimated/
Dissociation Constants:pKa1= 3.1; pKa2= 4.8; pKa3= 10.4
Experimental Properties:Crystals; decompose 240-250 °C; sparingly soluble in water. /dl-Folinic acid/|Hydroxyl radical reaction rate constant = 2.7X10-10 cu cm/molec-sec at 25 °C /Estimated/
Critical Temperature & Pressure:under inert gas (nitrogen or Argon) at 2–8 °C
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals
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Location:
Room A, 23rd Floor, No. 609 Yan'an Road, Gongshu District, Hangzhou, Zhejiang
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Payment Terms:
TT against copy of documents,D/P,L/C
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Average lead Time:
5 days
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Total Annual Revenue:
Above $100 million
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Year of Establishment:
2020
Company Certificates-
ISO
">Company ProfileLEAPChem is a specialized fine chemical supplier for research, development and production.
LEAPChem provides nearly 200,000 rare and innovative chemical products to support the evolving needs of our customers in research & bulk manufacturing activities.
As a highly customer-oriented enterprise, we are committed to providing high-quality customer services and products to our global customers in a cost-effective and efficient manner.
Our client list includes many major pharmaceutical and science companies, universities, research institutions and chemical catalogue companies.
Methodology: Sound & Stable; Active & Innovative.
Attitude: Conscientious; Ingenious.
Goals: Customer's Satisfaction
We regard client's success as our success.
At LEAPChem, we strive to be the preferred supplier for efficiency increasing and cost lowering in your Research & Production.
To achieve this strategic vision, we always push ourselves to exceed our customer's requirement. By focusing on the aim of 'Beyond Your Expectation', we continually expand our product lines, and enhance our systematic management and human resources.
Welcome to contact us and we look forward to becoming your reliable and preferred partner.
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Inquiry History5 Inquiries
Country Product Purchase Quantity Date Posted 
Qatar
folinic acid
1 KG Feb 27, 2024 
Latvia
Folinic acid
1 20' Fcl Mar 4, 2026 
Australia
Leucovorin
1 KG Oct 21, 2025 
Netherlands
Folinic acid
5 KG Mar 18, 2026 
United States
leucovorin
10 MG Sep 23, 2025 Post an enquiry for this product
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