Corynoxine or Uncaria Macrophylla hooks Corynoxine as well as Corynoxine B for mTor and mOR
2 Inquiries
6877-32-3
Industrial Grade
99%
Shanghai
SX
25kg
2026-10-04
HPMC,Lithium Carbonate,Cellulose Acetate Tow,EVA resin,Terpene Resin,PP fiber
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceCorynoxine is an enantiomer of Corynoxine B; induces autophagy in different neuronal cell lines, including N2a and SHSY-5Y cells.IC50 value:Tareget: Autophagy inducerIn vivo, Cory promotes the formation of autophagosomes in the fat bodies of Drosophila. By inducing autophagy, Cory promotes the clearance of wild-type and A53T α-syn in inducible PC12 cells. Interestingly, different from its enantiomer Cory B, Cory induces autophagy through the Akt/mTOR pathway as evidenced by the reduction
Corynoxine is a member of indolizines. It has a role as a metabolite.Basic Info-
Product Name:
Corynoxine
Other Name:Spiro[3H-indole-3,1′(5′H)-indolizine]-7′-acetic acid,6′-ethyl-1,2,2′,3′,6′,7′,8′,8′a-octahydro-α-(methoxymethylene)-2-oxo-,methyl ester,(αE,1′S,6′S,7′S,8′aS)-;Corynoxine;Corynoxan-16-carboxylic acid,16,17-didehydro-17-methoxy-2-oxo-,methyl ester,(16E)-;Spiro[3H-indole-3,1′(5′H)-indolizine]-7′-acetic acid,6′-ethyl-1,2,2′,3′,6′,7′,8′,8′a-octahydro-α-(methoxymethylene)-2-oxo-,methyl ester,[1′S-[1′α,6′β,7′β(E),8′aα]]-;28645-82-1
CAS No.:6877-32-3
Molecular Formula:C22H28N2O4
InChIKeys:InChIKey=DAXYUDFNWXHGBE-NRAMRBJXSA-N
Molecular Weight:384.473
Exact Mass:384.47
Categories:
Characteristics-
PSA:
67.87000
XLogP3:3.31
Density:1.2±0.1 g/cm3
Melting Point:166-168 °C
Boiling Point:560.8±50.0 °C at 760 mmHg
Flash Point:293.0±30.1 °C
Refractive Index:1.596
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 2, Oral
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H300 Fatal if swallowed
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Response P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
HPMC,Lithium Carbonate,Cellulose Acetate Tow,EVA resin,Terpene Resin,PP fiber
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Location:
Building 4, Feicui Building, No. 366 Xinshi North Road, Qiaoxi District, Shijiazhuang City, Hebei Province
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Payment Terms:
TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
7
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Total Annual Revenue:
$5 million-$10 million
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Total Employees:
51-100
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Year of Establishment:
2024
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Inquiry History2 Inquiries
Country Product Purchase Quantity Date Posted 
United States
Corynoxine
1 KG Sep 4, 2026
United States
Corynoxine
1 KG Sep 3, 2026 Post an enquiry for this product
