High Purity Synthetic Cagrilintide Peptide Lyophilized Powder for Preclinical Metabolic Study

Product Introduction

Cagrilintide, also known as AM833, is a synthetic lipidated research peptide and structural analog of endogenous amylin. It is constructed with optimized peptide sequence and terminal lipid modification to extend molecular stability for laboratory testing. This compound is widely applied for preclinical research focusing on neuroendocrine signaling and metabolic biological pathways. Different from many metabolic research peptides acting on incretin receptors, it interacts with amylin and calcitonin related receptor complexes. Our product is offered as high-purity lyophilized powder, strictly restricted to laboratory research applications only. Each batch undergoes verification via HPLC and MS, and complete COA documents can be provided upon request.

Chemical Information

• Common Name: Cagrilintide
  
  
  Alias: AM833
  
  
  CAS: 1415456-99-3
  
  
  Amino Acid Sequence: Eicosanedioic acid-γ-Glu-Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Glu-Phe-Leu-Arg-His-Ser-Ser-Asn-Asn-Phe-Gly-Pro-Ile-Leu-Pro-Pro-Thr-Asn-Val-Gly-Ser-Asn-Thr-Pro-NH₂ (Disulfide bridge between Cys3 and Cys8)
  
  
  Appearance: White lyophilized powder
  
  
  Purity: ≥99%
  
  
  Solubility: Soluble in sterile aqueous solution and PBS buffer
  
  
  Form: Lyophilized powder
  
  
  Application: Laboratory research only

Mechanism of Action

Cagrilintide functions as a dual modulator targeting amylin receptor complexes and calcitonin receptors. After molecular binding, it initiates intracellular signal cascades within relevant cell populations. The structural lipid modification supports prolonged circulation stability in research models. Researchers utilize this unique molecular pathway to investigate neuroendocrine signal transmission, energy balance regulation and related biological metabolic processes.

Storage Condition