China Origin 99.0% Purity Delta Sleep-Inducing Peptide DSIP Freeze-dried Powder, CAS#62568-57-4 with 10mg

Product Name: DSIP (δ-Sleep-Inducing Peptide) Lyophilized Peptide Powder, Research Grade Laboratory Reagent, CAS No.: 62568-57-4, HPLC Purity ≥99%, Suitable for Sleep and Neuroprotective Research

Full Product Description:

DSIP, short for δ-Sleep-Inducing Peptide, also known as emitidine, is a well-studied endogenous nonapeptide with significant research value in sleep physiology, neuroprotection, and stress response regulation. This product is a research-grade lyophilized peptide powder provided by Novio, manufactured strictly according to laboratory research standards and verified by high-performance liquid chromatography (HPLC) with a purity ≥99%. Each batch comes with a complete Certificate of Analysis (COA) to meet the stringent quality requirements of academic laboratories, research institutions, and biochemical product distributors worldwide. Unlike many synthetic peptides, DSIP is a naturally occurring peptide, first isolated from rabbit cerebral venous blood in 1974, making it a reliable and safe tool for exploring sleep regulation and neurobiological mechanisms in preclinical research models.

2. Core Product Specifications

Numerous in vitro and preclinical laboratory studies have confirmed that DSIP exerts its biological effects through multiple key pathways, making it a widely used research tool in neurobiology and sleep science. Its core research mechanisms are as follows:

- Sleep Structure Regulation: DSIP is widely known for its ability to enhance slow-wave sleep (SWS, also known as delta sleep), which is crucial for physical recovery and cognitive function consolidation. Laboratory data show that DSIP can prolong deep sleep time, optimize the balance between rapid eye movement (REM) sleep and non-rapid eye movement (NREM) sleep, and improve sleep quality without inducing sedation or dependence, distinguishing it from traditional hypnotics. This mechanism makes it an ideal tool for studying sleep regulation and developing non-addictive sleep regulators.

- Neuroprotective and Antioxidant Activity: DSIP has been shown to possess significant antioxidant properties, capable of scavenging free radicals and reducing neuronal damage caused by oxidative stress. It can protect nerve cells from ischemic and hypoxic damage, regulate neurotransmitter release, and support synaptic plasticity, showing potential protective effects in preclinical models of neurodegenerative diseases such as Alzheimer's and Parkinson's. 

- Stress response and hypothalamic-pituitary-adrenal (HPA) axis regulation: DSIP can regulate the activity of the hypothalamic-pituitary-adrenal (HPA) axis, reduce cortisol levels, and alleviate stress responses in preclinical animal models. It also possesses anti-anxiety properties, interacting with the GABAergic and opioid systems, making it an important research tool for exploring the neurobiological mechanisms of anxiety, post-traumatic stress disorder (PTSD), and stress. In addition, studies have shown that it can alleviate withdrawal symptoms of alcohol and opioids, providing support for research into addiction mechanisms.