Isorhamnetin 7-O-α-L-rhamnoside 98% Purity Natural Product Reference Standard CAS 17331-72-5 Research Grade Flavonoid Glycoside Rhamnoside

• • Product Overview

    Isorhamnetin 7-O-α-L-rhamnoside is a monoglycosylated flavonoid compound in which the isorhamnetin aglycone is substituted with an α-L-rhamnopyranosyl moiety at the 7-hydroxyl position. With the molecular formula C₂₂H₂₂O₁₁ and a molecular weight of approximately 462.41 g/mol, this compound appears as an off-white to pale yellow crystalline powder. It is a valuable reference material for phytochemical analysis and flavonoid metabolism studies, commonly isolated from plants of the Rhamnaceae and Polygonaceae families.

    Biosynthetic Origin

    This compound is biosynthesized in plants through the flavonoid pathway, where the aglycone isorhamnetin undergoes site-specific glycosylation at the 7-hydroxyl group catalyzed by rhamnosyltransferases. The presence of the rhamnose moiety imparts distinct physicochemical properties compared to its 3-O-glycosylated analogs.

    Research Applications

    • Structural Characterization: Serves as a model compound for NMR and MS-based structural elucidation of flavonoid glycosides, particularly for distinguishing 7-O- vs 3-O-glycosylation patterns

    • Metabolism Studies: Used in in vitro and in vivo studies to investigate the metabolic fate of flavonoid glycosides, including deglycosylation pathways and phase II metabolism

    • Enzyme Inhibition Research: Evaluated for potential inhibitory activity against carbohydrate-hydrolyzing enzymes (α-glucosidase, α-amylase) and lipases

    • Quality Control Marker: Acts as a characteristic marker compound for botanical extracts containing isorhamnetin derivatives

    • Chemotaxonomic Studies: Aids in plant classification and identification based on glycosylation patterns

    Quality Specifications

    Our isorhamnetin 7-O-α-L-rhamnoside is manufactured under strict quality control conditions:

    • Purity: ≥98.0% determined by HPLC (area normalization)

    • Identification: Confirmed by NMR (¹H, ¹³C) and high-resolution MS

    • Appearance: Off-white to pale yellow powder

    • Solubility: Soluble in DMSO, methanol, and ethanol

    • Each batch accompanied by comprehensive Certificate of Analysis (COA)

    • Stable for 24 months when stored at 2-8°C in sealed containers protected from light

    Packaging & Shipping

    We offer flexible packaging options to meet diverse research needs:

    • Standard packaging: 5mg amber glass vial

    • Bulk quantities available upon request

    • Shipped at ambient temperature

    • International shipping available with proper documentation

    • Recommended storage: 2-8°C, protected from light and moisture

Jinan Topfull Chemical Co., Ltd. is an international company rooted in China, specializing in the export of chemical products.

Our company is committed to making every effort to provide ideal chemical products to potential customers worldwide, including but not limited to: organic/inorganic reagents, biological reagents, plant extracts, pharmaceutical intermediates, active pharmaceutical ingredients (APIs), reference standards, reference substances, peptides, and more. Meanwhile, we have established long-term and stable cooperative relationships with university laboratories and off-campus research institutions, enabling us to offer tailored product services based on customers' actual needs.

We currently support customized services for most product categories, with supply quantities ranging from milligram (mg), gram (g) to kilogram (kg) levels, as well as wholesale. Product purity covers the full spectrum from 90% to 99.9%, providing customers with one-stop convenient services.

To date, our products have been exported to developed countries such as the United States, Australia, Canada, Mexico, as well as EU member states including France, Germany, and many other countries and regions such as Nigeria, Ghana, Southeast Asia, and other parts of Asia. Our product quality and services have consistently received high praise.

Looking ahead, our company will continue to serve as a bridge connecting China and the world, delivering high-quality products and services to global customers.