L-(+)-Rhamnose Monohydrate 98% Purity Natural Sugar Reference Standard CAS 10030-85-0 Research Grade Monosaccharide

Product Overview

L-(+)-Rhamnose Monohydrate is a naturally occurring deoxy sugar, specifically a 6-deoxy-L-mannose, primarily found in plants and some bacteria. It forms a major structural component of plant cell walls and is also bound to other compounds, such as phenolics . Unlike most natural sugars, it is found in an L-configuration instead of the usual D-configuration, which contributes to its unique biological properties . The monohydrate form is the stable crystalline state, with the molecular formula C₆H₁₂O₅·H₂O and a molecular weight of 182.17 g/mol . It appears as a white to off-white crystalline powder and has a biological source of oranges .

Mechanism of Action & Biological Significance

L(+)-Rhamnose is a deoxy sugar that can bind to certain proteins and enzymes, which can lead to changes in their structure and function . It is believed to act as a signaling molecule, influencing the expression of certain genes . It is a natural monosaccharide with cell-promoting and anti-inflammatory properties, targeting cells that express lectins capable of recognizing L-rhamnose, such as keratinocytes and dermal papilla fibroblasts . Due to its anti-inflammatory and skin-soothing properties, it is being promoted for use in anti-wrinkle agents .

Research Applications & Significance

The unique properties of L-(+)-Rhamnose make it a valuable tool in various research fields:

• Microbiology & Metabolism: It is used in studies of bacterial cell wall structure, as a component of bacterial fermentation media, and in polysaccharide composition analysis .

• Intestinal Permeability & Absorption: It crosses epithelia via the transcellular pathway and can be used as a marker for intestinal absorption .

• Natural Product Chemistry: It is a key moiety in many plant glycosides and a precursor in the synthesis of various rhamnoside-containing natural products.

• Analytical Chemistry: It serves as a reference standard for carbohydrate analysis using techniques such as HPLC, GC, and TLC.

Quality Specifications

Our L-(+)-Rhamnose Monohydrate is manufactured under strict quality control conditions:

• Purity: ≥98.0% determined by HPLC .

• Appearance: White to almost white powder to crystal .

• Melting Point: 90.0°C to 95.0°C .

• Specific Rotation: +7.8 to +8.5° (c=10, H₂O) ; or +8.2° to +8.9° (c=4.5, H₂O) .

• pH Range: 7.8 to 8.6 .

• Water Solubility: 300 g/L at 20°C ; Freely soluble in water and DMSO, soluble in methanol and ethanol.

• Storage Condition: Store in a cool, dry place at room temperature (recommended below 15°C) in sealed containers . For long-term storage, the powder form can be stored at -20°C for up to 3 years .

• Each batch is accompanied by a comprehensive Certificate of Analysis (COA).

Packaging & Shipping

We offer flexible packaging options to meet diverse research needs:

• Research quantities: Standard packaging in amber glass vials, with options including 20mg, 100mg, 1g, 5g, 10g, 25g, and 100g bottles.

• Bulk quantities: Available upon request.

• Shipping: Shipped at ambient temperature. Not classified as a hazardous material for transport .

• International shipping available with proper documentation.

• Recommended storage: Store in a cool, dry place at room temperature (recommended below 15°C) in sealed containers, protected from light and moisture.