high purity Selank peptide;SelankAcetate;PL14736;Anxiolytic (GABA-A modulation)/peptide raw material

Description

Selank is a synthetic heptapeptide with the amino acid sequence threonine - lysine - proline - arginine - proline - glycine - proline (TKPRPGP), CAS No. 129954-34-3, molecular formula C₃₃H₅₇N₁₁O₉, molecular weight 751.87. It was first developed by Russian research institutions in the early 1990s and is a synthetic analog of the phagocytosis-promoting peptide (tuftsin). By extending the structure of the original sequence, its metabolic stability has been enhanced. This product is supplied as a high-purity (≥99%, as determined by HPLC) lyophilized white powder. It is stable, easy to store, and convenient for experimental preparation, and can be used directly in various scientific research experiments.

Key Effects

Selank’s research value lies primarily in the field of neuromodulation. As a synthetic modulatory peptide belonging to the tuftsin family, it has been observed in relevant experiments to possess modulatory activity on the nervous system, particularly in anxiety-related behavioral studies; at the same time, it is also believed to be associated with immunomodulatory processes, making it valuable for research into both the nervous and immune systems. Because its sequence has been modified for metabolic stability, it has a relatively long duration of action, making it suitable for systematic research and observation.

1. Neuromodulatory Effects: Anxiety-related modulatory activity has been observed in animal behavioral experiments, making it a commonly used tool peptide in research on anxiety mechanisms.

2. Research Value for Cognitive Function: Some experimental data indicate that it holds certain research value for processes related to learning and memory.

3. Immunomodulatory Activity: As a tuftsin analog, it is closely related to research on immunomodulatory mechanisms.

4. Good Metabolic Stability: Following structural modification, its duration of action has been extended, making it suitable for long-term observational experiments.

Applications

Selank is currently used primarily in scientific research in the field of neuroscience, covering multiple research areas such as the mechanisms of anxiety, cognitive function, and stress responses. It is also a representative compound in interdisciplinary research on neuropeptides and the immune system and has garnered significant attention in the field of neuromodulatory peptide research.

1. Anxiety and Stress Research: Used in anxiety-related behavioral experiments and mechanism exploration in animal models.

2. Cognitive Function Research: Used in experimental studies of learning and memory-related processes.

3. Neuroimmunology Research: Serves as a tool compound for investigating the interaction between neuropeptides and the immune system.

4. Drug Discovery Reference: As a representative molecule for the synthesis of regulatory peptides, it is used in the development of novel neuromodulatory peptide drugs.

5. Standard Reference Material: Used for the development of relevant peptide detection methods and quality control.