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Home > Natural Products > Alkaloids > Tetrahydroalstonine for Sale > Tetrahydroalstonine 98% Purity CAS 6474-90-4 Indole Alkaloid for Anticancer and Neuroprotective Research Reagent Grade
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Tetrahydroalstonine 98% Purity CAS 6474-90-4 Indole Alkaloid for Anticancer and Neuroprotective Research Reagent Grade

Unit Price: Get Latest Price
CAS No.:

6474-90-4

Grade:

Reagent Grade

Content:

98%

Port:

Qingdao

Brand:

//

Packaging:

5mg/vial; 10mg, 20mg, 50mg, 100mg and bulk quantities available upon request

Sample Available:

Yes

Price valid (until):

2026-10-10

Company Type:
Trader
Location:
China
Payment Terms:
TT against copy of documents,TT against B/L draft before shipment,100% TT in advance
Average Lead Time:
7 days
Qualification:
Main Products:

Medetomidine,Medetomidine hydrochloride,D-Lysergic Acid Methyl Ester,SR17018,Fluralaner,GS-441524

  • Product Details

  • Seller Information

  • Description

    Shop Tetrahydroalstonine 98% Purity CAS 6474-90-4 Indole Alkaloid for Anticancer and Neuroprotective Research Reagent Grade-Detailed Image 1

      • Product Overview

        Tetrahydroalstonine is a naturally occurring indole alkaloid found in various plant species. It is a tetrahydro derivative of alstonine, with a fully saturated tetrahydro-β-carboline core. This product is a high-purity research-grade reagent with a purity of ≥98% as determined by HPLC analysis, appearing as a white to off-white powder. It is primarily used in anticancer research, neuroprotective research, and natural product chemistry.

        Chemical Properties

        • Molecular Formula: C₂₁H₂₄N₂O₃

        • Molecular Weight: 352.43 g/mol

        • Synonyms: Tetrahydroalstonine

        • Solubility: Soluble in DMSO, methanol, ethanol

        Natural Source

        Tetrahydroalstonine is found in various plant species of the Apocynaceae family, including Alstonia species and Rauvolfia species. It is a biosynthetic precursor or derivative of alstonine.

        Biological Activity

        • Anticancer Activity: Has been studied for its cytotoxic effects against cancer cell lines.

        • Neuroprotective Activity: Research suggests potential neuroprotective effects.

        • Natural Product Chemistry: Serves as a reference compound for the study of indole alkaloids.

        Quality Specifications

        • Purity: ≥98.0%

        • Appearance: White to off-white powder

        • Identification: Conforms to structure by NMR and Mass Spectrometry

        • Loss on Drying: ≤0.5%

        • Residue on Ignition: ≤0.1%

        • Heavy Metals: ≤10 ppm

        Packaging & Storage

        • Packaging: Available in 5mg-100mg amber glass vials. Larger quantities available upon request.

        • Storage: Store at 2-8°C, sealed, protected from light.

        • Shelf Life: 36 months.

    Parameter Specification Details
    Product Name Tetrahydroalstonine Indole alkaloid
    CAS Number 6474-90-4
    Molecular Formula C₂₁H₂₄N₂O₃
    Molecular Weight 352.43 g/mol
    Appearance White to off-white powder Visual inspection
    Purity ≥98.0% Determined by HPLC area normalization
    Solubility Soluble in DMSO, methanol, ethanol
    Identification Conforms to structure Verified by NMR and Mass Spectrometry
    Storage Condition 2-8°C/36mo
    Shelf Life 36 months From date of manufacture
    Packaging 5mg-100mg; Customizable
    Price $1.50-2.50/mg Based on 5mg reference price
    Application Research use only Anticancer research, neuroprotective research
    Shop Tetrahydroalstonine 98% Purity CAS 6474-90-4 Indole Alkaloid for Anticancer and Neuroprotective Research Reagent Grade-Detailed Image 2
    Shop Tetrahydroalstonine 98% Purity CAS 6474-90-4 Indole Alkaloid for Anticancer and Neuroprotective Research Reagent Grade-Detailed Image 3

    Jinan Topfull Chemical Co., Ltd. is an international company rooted in China, specializing in the export of chemical products.

    Our company is committed to making every effort to provide ideal chemical products to potential customers worldwide, including but not limited to: organic/inorganic reagents, biological reagents, plant extracts, pharmaceutical intermediates, active pharmaceutical ingredients (APIs), reference standards, reference substances, peptides, and more. Meanwhile, we have established long-term and stable cooperative relationships with university laboratories and off-campus research institutions, enabling us to offer tailored product services based on customers' actual needs.

    We currently support customized services for most product categories, with supply quantities ranging from milligram (mg), gram (g) to kilogram (kg) levels, as well as wholesale. Product purity covers the full spectrum from 90% to 99.9%, providing customers with one-stop convenient services.

    To date, our products have been exported to developed countries such as the United States, Australia, Canada, Mexico, as well as EU member states including France, Germany, and many other countries and regions such as Nigeria, Ghana, Southeast Asia, and other parts of Asia. Our product quality and services have consistently received high praise.

    Looking ahead, our company will continue to serve as a bridge connecting China and the world, delivering high-quality products and services to global customers.

    Shop Tetrahydroalstonine 98% Purity CAS 6474-90-4 Indole Alkaloid for Anticancer and Neuroprotective Research Reagent Grade-Detailed Image 4
    ECHEMI Editorial Reference
    Tetrahydroalstonine, a indole alkaloid isolated from the fruits of Rhazya stricta, is a selective alpha 2-adrenoceptor antagonist[1][2].
    Tetrahydroalstonine is a heteropentacyclic compound that is (20alpha)-16,17-didehydro-18-oxayohimban which is substituted at position 16 by a methoxycarbonyl group and at position 19 by a methyl group. It is a metabolite found in several plant species. It has a role as a plant metabolite. It is a yohimban alkaloid, an organic heteropentacyclic compound and a methyl ester. It is a conjugate base of a tetrahydroalstonine(1+).

    Basic Info
    Product Name:

    Tetrahydroalstonine

    Other Name:

    Oxayohimban-16-carboxylic acid,16,17-didehydro-19-methyl-,methyl ester,(19α,20α)-;Alstonine,3,4,5,6-tetrahydro-;Tetrahydroalstonine;Alstonine,3,4,5,6-tetrahydro-,(3α)-;(-)-Tetrahydroalstonine;(3α)-3,4,5,6-Tetrahydroalstonine;4H-Indolo[2,3-a]pyrano[3,4-g]quinolizine-1-carboxylic acid,4a,5,7,8,13,13b,14,14a-octahydro-4-methyl-,methyl ester,(4S,4aS,13bS,14aS)-;NSC 72115

    CAS No.:

    6474-90-4

    Molecular Formula:

    C21H24N2O3

    InChIKeys:

    InChIKey=GRTOGORTSDXSFK-DLLGKBFGSA-N

    Molecular Weight:

    352.43

    Exact Mass:

    352.43

    EC Number:

    229-331-0

    UNII:

    6U62R2Y5Y2

    Categories:

    Alkaloids

    Characteristics
    PSA:

    54.56000

    XLogP3:

    2.88

    Density:

    1.3±0.1 g/cm3

    Melting Point:

    230-231 °C

    Boiling Point:

    524.0±50.0 °C at 760 mmHg

    Flash Point:

    270.7±30.1 °C

    Refractive Index:

    1.656

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 4, Oral

    Acute toxicity - Category 4, Dermal

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H302 Harmful if swallowed

    H312 Harmful in contact with skin

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    Response

    P301+P317 IF SWALLOWED: Get medical help.

    P330 Rinse mouth.

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P317 Get medical help.

    P321 Specific treatment (see ... on this label).

    P362+P364 Take off contaminated clothing and wash it before reuse.

    Storage

    none

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Medetomidine,Medetomidine hydrochloride,D-Lysergic Acid Methyl Ester,SR17018,Fluralaner,GS-441524

    Location:

    RONGSHENG BEIYUANDAJIE 9, LICHENG DISTRICT,JINAN, SHANDONG CHINA

    Payment Terms:

    TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    7 days

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    11-50

    Year of Establishment:

    2022

    Jinan Topfull Chemical Co., Ltd. is a global chemical Industrial and focuses on advanced chemical technology. Specialized in Cosmetic materials, water treatment, fine chemicals and so on. We are looking forward to working together with the people of all circles at home and abroad to seek common development!
  • Country Product Purchase Quantity Date Posted
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