2-Bromoimidazo[1,2-b]pyridazine-6-carboxylic acid 97% Purity CAS 1315363-83-7 Brominated Heterocyclic Intermediate for Pharmaceutical Research

• • • • • • • • • • • Product Overview

                      2-Bromoimidazo[1,2-b]pyridazine-6-carboxylic acid is a brominated fused heterocyclic compound containing an imidazo[1,2-b]pyridazine core with a bromine atom at the 2-position and a carboxylic acid group at the 6-position. The bromine atom provides a versatile handle for cross-coupling reactions, while the carboxylic acid enables further derivatization, making this compound a valuable building block for the synthesis of pharmaceutical candidates and bioactive molecules.

                      Chemical Properties

                      • Molecular Formula: C₇H₄BrN₃O₂

                      • Molecular Weight: 242.03 g/mol

                      • Synonyms: 2-Bromoimidazo[1,2-b]pyridazine-6-carboxylic acid

                      • Solubility: Soluble in DMSO, methanol, ethanol

                      Synthetic Utility

                      The bromine substituent enables palladium-catalyzed coupling reactions, including Suzuki, Sonogashira, and Buchwald-Hartwig couplings. The carboxylic acid at the 6-position can undergo amidation, esterification, and decarboxylative coupling reactions.

                      Quality Specifications

                      • Purity: ≥97.0% (determined by HPLC area normalization)

                      • Appearance: Off-white to pale yellow powder

                      • Identification: Conforms to structure by NMR and Mass Spectrometry

                      • Loss on Drying: ≤0.5%

                      • Residue on Ignition: ≤0.1%

                      • Heavy Metals: ≤10 ppm

                      • Each batch is accompanied by a comprehensive Certificate of Analysis (COA).

                      Packaging & Storage

                      • Packaging: Available in 1g-1kg packaging. Custom packaging available upon request.

                      • Storage: Store at 2-8°C, sealed, protected from light.

                      • Shelf Life: 24 months when stored under recommended conditions.

Jinan Topfull Chemical Co., Ltd. is an international company rooted in China, specializing in the export of chemical products.

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We currently support customized services for most product categories, with supply quantities ranging from milligram (mg), gram (g) to kilogram (kg) levels, as well as wholesale. Product purity covers the full spectrum from 90% to 99.9%, providing customers with one-stop convenient services.

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