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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Rivaroxaban for Sale > Rivaroxaban CAS 366789-02-8 Factor Xa Inhibitor for Stroke and VTE Prevention hfd
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Rivaroxaban CAS 366789-02-8 Factor Xa Inhibitor for Stroke and VTE Prevention hfd

TDS 13 Inquiries

Unit Price:

$100-130/G FOB

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CAS No.:

366789-02-8

Grade:

Reagent Grade

Content:

99%

Port:

qingdao

Brand:

//

Packaging:

5g, 25g, 100g, 500g

Price valid (until):

2026-09-19

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Medetomidine,Medetomidine hydrochloride,D-Lysergic Acid Methyl Ester,SR17018,Fluralaner,GS-441524

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

    —— Product Specification ——

    Parameter Specification Details
    Product Name Rivaroxaban Xarelto; BAY 59-7939
    CAS Number 366789-02-8 366789-02-8
    Molecular Formula C₁₉H₁₈ClN₃O₅S
    Molecular Weight 435.88 g/mol
    Appearance White to off-white solid powder Visual inspection
    Purity ≥98.0% Determined by HPLC
    Melting Point 228 – 234°C
    Optical Rotation -41° (c=0.3, DMSO)
    Solubility DMSO: ≥10 mg/mL; practically insoluble in water
    Storage 2-8°C (short-term); -20°C (long-term) Sealed containers, protect from light and moisture
    Packaging 10mg, 25mg, 50mg, 100mg, 200mg, 500mg, 1g Amber glass vials
    Application Research and analytical use only Pharmaceutical research, anticoagulant studies, reference standard


    —— Product Detail ——

    Product Overview

    • Rivaroxaban (CAS 366789-02-8), also known as Xarelto or BAY 59-7939, is an oxazolidinone derivative that functions as a direct, reversible, and highly potent inhibitor of Factor Xa (FXa) with a Ki in the low nanomolar range . It appears as a white to off-white solid powder with the molecular formula C₁₉H₁₈ClN₃O₅S and a molecular weight of 435.88 g/mol . Its IUPAC name is 5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide .


    Packaging & Shipping

                  • Research quantities: 5mg, 10mg, 25mg amber glass vials

                  • Bulk quantities: 50mg, 100mg amber glass bottles

                  • Custom packaging available upon request

                  • Not classified as hazardous material for transport under normal conditions

                  • Product for research and analytical use only; not for human therapeutic use

    Shop CAS 18048-64-1 Eltrombopag Intermediate for Pharmaceutical Research  kr-Detailed Image 1

    Company profile ——


     Shop CAS 1231930-42-9 Abemaciclib Intermediate for Pharma researech use KR-Detailed Image 1

    Jinan Topfull Chemical Co., Ltd. is an international company rooted in China, specializing in the export of chemical products.

    Our company is committed to making every effort to provide ideal chemical products to potential customers worldwide, including but not limited to: organic/inorganic reagents, biological reagents, plant extracts, pharmaceutical intermediates, active pharmaceutical ingredients (APIs), reference standards, reference substances, peptides, and more. Meanwhile, we have established long-term and stable cooperative relationships with university laboratories and off-campus research institutions, enabling us to offer tailored product services based on customers' actual needs.

    We currently support customized services for most product categories, with supply quantities ranging from milligram (mg), gram (g) to kilogram (kg) levels, as well as wholesale. Product purity covers the full spectrum from 90% to 99.9%, providing customers with one-stop convenient services.

    To date, our products have been exported to developed countries such as the United States, Australia, Canada, Mexico, as well as EU member states including France, Germany, and many other countries and regions such as Nigeria, Ghana, Southeast Asia, and other parts of Asia. Our product quality and services have consistently received high praise.

    Looking ahead, our company will continue to serve as a bridge connecting China and the world, delivering high-quality products and services to global customers.

     

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    —— Q&A ——

    Q1: How to confirm the product quality before placing orders?
    A: By sending you available samples. Or if you have special requirements for the goods, we can prepare samples according to your requirements for confirmation.

    Q2: Can you supply free samples?
    A: Yes, we can provide a free sample, but the shipping cost will be paid by the customers. You can either pay the shipping cost or arrange a courier to collect the samples.

    Q3: How do you treat quality complaints?
    A: All our products are strictly tested by our QC and confirmed by QA; unqualified material will not be released to customers. If any quality problem is confirmed to be caused by us, we will replace the goods or refund your payment immediately.

    Q4: What is your MOQ? Is there a discount?
    A: For highvalue products, our MOQ starts from 1g and generally starts from 10g. For other lowprice products, our MOQ starts from 100g and 1kg.
    Q: Is there a discount?
    A: Yes, for larger quantities, we always support with better prices.

    Q5: How to start orders or make payments?
    A: You can send us your Purchase Order (if your company has one), or just send a simple confirmation by email or via Trade Manager. We will then send you a Proforma Invoice with our bank details for your confirmation, and you can make payment accordingly. If you have other preferred payment methods, we are open to discussion and negotiation.



    ECHEMI Editorial Reference
    Rivaroxaban is a highly potent and selective, direct Factor Xa (FXa) inhibitor, achieving a strong gain in anti-FXa potency (IC50 0.7 nM; Ki 0.4 nM).
    Rivaroxaban is a monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-chlorothiophene-2-carboxylic acid with the amino group of 4-{4-[(5S)-5-(aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl}morpholin-3-one. An anticoagulant used for prophylaxis of venous thromboembolism in patients with knee or hip replacement surgery. It has a role as an anticoagulant and an EC 3.4.21.6 (coagulation factor Xa) inhibitor. It is a member of thiophenes, an organochlorine compound, an oxazolidinone, a member of morpholines, a lactam, an aromatic amide and a monocarboxylic acid amide.|Rivaroxaban is an anticoagulant and the first orally active direct factor Xa inhibitor. Unlike warfarin, routine lab monitoring of INR is not necessary. However there is no antidote available in the event of a major bleed. Only the 10 mg tablet can be taken without regard to food. The 15 mg and 20 mg tablet should be taken with food. FDA approved on July 1, 2011.|Rivaroxaban is a Factor Xa Inhibitor. The mechanism of action of rivaroxaban is as a Factor Xa Inhibitor.|Edoxaban is an oral, small molecule inhibitor of factor Xa which is used as an anticoagulant to decrease the risk of venous thromboses, systemic embolization and stroke in patients with atrial fibrillation, and as treatment of deep vein thrombosis and pulmonary embolism to prevent thrombotic complications. Edoxaban has been linked to a low rate of serum aminotransferase elevations during therapy, but has not been implicated in cases of clinically apparent acute liver injury.|Rivaroxaban is a recently developed oral anticoagulant and direct factor Xa inhibitor which is used in the prevention of stroke and venous embolism in patients with chronic atrial fibrillation, as well as treatment and prevention of deep venous thromboses and pulmonary embolism. Rivaroxaban has been associated with a low rate of serum enzyme elevations during treatment and with rare instances of clinically apparent liver injury with jaundice.|Rivaroxaban is an orally bioavailable oxazolidinone derivative and direct inhibitor of the coagulation factor Xa with anticoagulant activity. Upon oral administration, rivaroxaban selectively binds to both free factor Xa and factor Xa bound in the prothrombinase complex. This interferes with the conversion of prothrombin (factor II) to thrombin and eventually prevents the formation of cross-linked fibrin clots. Rivaroxaban does not affect existing thrombin levels.|A morpholine and thiophene derivative that functions as a FACTOR XA INHIBITOR and is used in the treatment and prevention of DEEP-VEIN THROMBOSIS and PULMONARY EMBOLISM. It is also used for the prevention of STROKE and systemic embolization in patients with non-valvular ATRIAL FIBRILLATION, and for the prevention of atherothrombotic events in patients after an ACUTE CORONARY SYNDROME.

    Certificates
    • Rivaroxaban CAS 366789-02-8 Factor Xa Inhibitor for Stroke and VTE Prevention hfd Certificates 1 TDS

    Basic Info
    Product Name:

    Rivaroxaban

    Other Name:

    2-Thiophenecarboxamide,5-chloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-;5-Chloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-2-thiophenecarboxamide;Rivaroxaban;BAY 59-7939;5-Chloro-N-[[(S)-3-(4-(3-oxomorpholin-4-yl)phenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl]-thiophene-2-carboxamide;Xarelto;5-Chloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-1,3-oxazolidin-5-yl]methyl]-2-thiophenecarboxamide;5-Chloro-N-([(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl]-methyl)-2-thiophenecarboxamide;(S)-Rivaroxaban;869880-21-7;931117-62-3;1807854-46-1

    CAS No.:

    366789-02-8

    Molecular Formula:

    C19H18ClN3O5S

    InChIKeys:

    InChIKey=KGFYHTZWPPHNLQ-AWEZNQCLSA-N

    Molecular Weight:

    435.88

    Exact Mass:

    435.88

    EC Number:

    1308068-626-2

    UNII:

    9NDF7JZ4M3

    DSSTox ID:

    DTXSID3057723

    NCI Thesaurus Code:

    C77995

    Color/Form:

    White to yellowish powder

    ATC Code:

    B01AF01|B - Blood and blood forming organs

    Characteristics
    PSA:

    116

    XLogP3:

    2.5

    Appearance:

    1

    Density:

    1.5±0.1 g/cm3

    Melting Point:

    230 °C

    Boiling Point:

    732.6°C at 760 mmHg

    Flash Point:

    396.9±32.9 °C

    Refractive Index:

    1.633

    Water Solubility:

    Slightly soluble in organic solvents (e.g. acetone, polyethylene glycol 400) and is pratically insoluble in water and aqueous media

    Storage Conditions:

    Refrigerator

    Vapor Pressure:

    6.66X10-16 mm Hg at 25 deg C (est)

    Odor:

    Odorless

    Henrys Law Constant:

    Henry's Law constant = 9,46X10-85 atm-cu m/mol at 25 °C (est)

    Hazard Identification

    Classification of the substance or mixture

    Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    No signal word

    Hazard statement(s)

    H411 Toxic to aquatic life with long lasting effects

    Precautionary statement(s)
    Prevention

    P273 Avoid release to the environment.

    Response

    P391 Collect spillage.

    Storage

    none

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Medetomidine,Medetomidine hydrochloride,D-Lysergic Acid Methyl Ester,SR17018,Fluralaner,GS-441524

    Location:

    RONGSHENG BEIYUANDAJIE 9, LICHENG DISTRICT,JINAN, SHANDONG CHINA

    Payment Terms:

    TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    7

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    11-50

    Year of Establishment:

    2022

    Jinan Topfull Chemical Co., Ltd. is a global chemical Industrial and focuses on advanced chemical technology. Specialized in Cosmetic materials, water treatment, fine chemicals and so on. We are looking forward to working together with the people of all circles at home and abroad to seek common development!
  • Inquiry History
    13 Inquiries
    Country Product Purchase Quantity Date Posted
    India

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    100.00 KG Jan 8, 2026
    India

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    200.00 KG Aug 17, 2026
    India

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    1.00 KG Mar 8, 2026
    Pakistan

    Rivaroxaban

    1.00 KG Jan 23, 2026
    India

    Riveroxaban

    1 MG Dec 22, 2025
    India

    Rivaroxaban

    500 G Aug 11, 2026
    India

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    India

    Rivaroxaban

    1.00 KG Mar 18, 2026
    India

    Rivaroxaban 

    1.00 KG Mar 11, 2026
    India

    Rivaroxaban

    500.00 KG Feb 2, 2026
    India

    Rivoraxaban IP

    10.00 KG Jan 22, 2026
    India

    Rivaroxaban

    15 KG Jul 29, 2025
    Pakistan

    Febuxostat

    800.00 KG Aug 4, 2026
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