 Home > Active Pharmaceutical Ingredients > Digestive System Drugs > Erdafitinib for Sale > High Purity Erdafitinib JNJ-42756493 Balversa FGFR Inhibitor Raw Powder 1G

High Purity Erdafitinib JNJ-42756493 Balversa FGFR Inhibitor Raw Powder 1G buy - large image1

High Purity Erdafitinib JNJ-42756493 Balversa FGFR Inhibitor Raw Powder 1G buy - image1

High Purity Erdafitinib JNJ-42756493 Balversa FGFR Inhibitor Raw Powder 1G buy - image2

High Purity Erdafitinib JNJ-42756493 Balversa FGFR Inhibitor Raw Powder 1G buy - image3

High Purity Erdafitinib JNJ-42756493 Balversa FGFR Inhibitor Raw Powder 1G buy - image4

High Purity Erdafitinib JNJ-42756493 Balversa FGFR Inhibitor Raw Powder 1G

Name: High Purity Erdafitinib JNJ-42756493 Balversa FGFR Inhibitor Raw Powder 1G
Brand: SUITAITRADE
SKU: pr2609142103
Price: 90 USD
Availability: InStock

562 Inquiries

Unit Price: Get Latest Price 

CAS No.:

1346242-81-6

Grade:

Pharmaceutical Grade

Content:

99%

Port:

HONGKONG

Brand:

SUITAITRADE

Packaging:

1g/bottle

Price valid (until):

2026-10-14

Contact Supplier

 Chat Now

STARBEAUTY BIOTECH LIMITED

Company Type:

Trader

Location:

Hongkong, China

Payment Terms:

TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

3 days

Qualification:

Main Products:

peptide,Cosmetics

 Visit Store

Product Description
Seller Information
Inquiry History

Description

Product Detail

Erdafitinib (JNJ-42756493, brand name Balversa), CAS:1346242-81-6. It is an orally bioavailable pan-FGFR tyrosine kinase inhibitor developed by Janssen, and the first FGFR inhibitor approved by FDA.
Mechanism: Potently inhibits FGFR1, FGFR2, FGFR3 and FGFR4. It blocks abnormal FGFR signaling caused by gene mutation, amplification or fusion, suppresses tumor cell proliferation and triggers apoptosis. It also has weak inhibitory activity on RET, PDGFRA, VEGFR2.
Research application: In vitro cell assay, in vivo xenograft model, oncology pharmacology research, mainly for solid tumors with FGFR alterations such as urothelial carcinoma, lung cancer and triple-negative breast cancer.

Items	Specifications
Name	Erdafitinib
CAS Number	1346242-81-6
Grade	Pharmaceutical Grade
Specification	1g
Purity	≥99% (Verified by HPLC)
Appearance	Yellow crystalline powder
Storage	Store at -20°C, sealed and protected from light. For research use only, not for human clinical administration.

Our Company

We are an enterprise integrating chemical research and development, production and trading, specializing in the operation of high-quality fine chemical products.
Company adopts an advanced management model, possesses a professional R&D team, strong technical strength, a complete quality assurance and control system, excellent sales and after-sales service, forming a complete system from product R&D, production, sales to after-sales service, ensuring the highest quality and timely delivery.
We are extremely committed to the collection and research and development of both new and old products. Adhering to the business philosophy of "sincerity and trustworthiness, customer satisfaction first", we follow the path of professional development and have won high praise and a good reputation from customers with excellent product quality and perfect and considerate services. To become a leading import and export enterprise of pharmaceuticals and chemicals in China. Processing capacity: The company has strong technical force and advanced testing equipment, and can provide high-quality products ranging from gram level to kilogram level and ton level. After-sales service: Made in China, reasonable price, superior quality. 24-hour online service. 3. Safe and fast global delivery. 4. High-quality after-sales service with customer satisfaction as the goal.

Shop High Purity Erdafitinib JNJ-42756493 Balversa FGFR Inhibitor Raw Powder 1G-Detailed Image 1

Shop High Purity Erdafitinib JNJ-42756493 Balversa FGFR Inhibitor Raw Powder 1G-Detailed Image 2

Shop High Purity Erdafitinib JNJ-42756493 Balversa FGFR Inhibitor Raw Powder 1G-Detailed Image 3

Our Advantages

1. Stable activity and reliable performance
Adopting mature synthesis and purification techniques, BC2 BC5 BC10 maintains stable biological activity. Strict impurity removal effectively avoids experimental data deviation, fully meeting high-standard testing requirements of academic laboratories and biotech research projects.
2. Standard specification for daily experiments
The 2mg, 5mg and 10mg standard specifications match most conventional laboratory tests and biochemical analysis. Each vial adopts vacuum lyophilization and light-proof sealed packaging, effectively preventing peptide oxidation and activity attenuation during transportation and daily storage.
3. Strict batch-to-batch quality consistency
All finished products undergo HPLC purity detection, molecular identity verification and moisture content testing before delivery. Unified production and inspection standards ensure stable and consistent quality among different batches.
4. Standard global logistics and safe transportation
We cooperate with experienced international logistics providers. Professional protective packaging is adopted for delivery, full tracking service is provided, and all transportation procedures comply with international import and export regulatory standards.
5. Adequate inventory and efficient delivery support
We keep sufficient spot inventory of BC2 BC5 BC10. Once payment is confirmed, we will finish sorting and delivery arrangement quickly to shorten the waiting time for laboratory research materials.
6. Professional technical consultation and after-sales service
Our professional team provides targeted guidance on reconstitution methods, storage rules and experimental application scenarios during working hours. All customer inquiries will be replied within 8 working hours.
7. Flexible long-term cooperation and preferential policies
For clients with long-term cooperation needs and bulk orders, we offer stable discounted prices and customized packaging solutions to reduce overall procurement costs of experimental supplies.

Shipping&Packaging

We offer multiple shipping solutions including dedicated line logistics and FedEx to ensure reliable and fast delivery. This guarantees stable tracking, on-time arrival, and minimal transit delays for your orders.

Shop High Purity Erdafitinib JNJ-42756493 Balversa FGFR Inhibitor Raw Powder 1G-Detailed Image 4

If you have any inquiry about product specifications, lab research solutions, bulk order discount and logistics arrangement, welcome to send messages to us via official platform chat box during working hours. Our team will reply to you promptly within 8 working hours.
Whatsapp: +852 5261 3144
Email: huang@suitaitrade.com

ECHEMI Editorial Reference

Erdafitinib (JNJ-42756493) is a potent and orally available FGFR family inhibitor; inhibits FGFR1/2/3/4 with IC50s of 1.2, 2.5, 3.0 and 5.7 nM, respectively.
In early April of 2019, the US FDA approved Janssen Pharmaceutical Companies' brand name Balversa (erdafitinib) as the first-ever fibroblast growth factor receptor (FGFR) kinase inhibitor indicated for patients with locally advanced or metastatic urothelial carcinoma, with susceptible FGFR3 or FGFR2 genetic alterations, that has progressed during or following platinum-containing chemotherapy, including within 12 months of neoadjuvant or adjuvant platinum-containing chemotherapy. At the same time, the FDA also approved the therascreen FGFR RGQ RT-PCR Kit (Qiagen) for utilization as a companion diagnostic with erdafitinib for selecting patients for the indicated therapy. Erdafitinib's innovation lies in the fact that it is the first personalized treatment targeting susceptible FGFR genetic alterations for patients with metastatic bladder cancer, which demonstrates the design of erdafitinib in developing more personalized and precision medicines with the capacity to target cancer treatment to a patient's specific genetic mutation. Considering urothelial cancer is statistically the fourth most common kind of cancer in the world, the introduction of erdafitinib offers a welcome new option in the ever-expanding therapeutic tool kit to treat such prevalent medical conditions. Nevertheless, although erdafitinib was granted Breakthrough Therapy designation and Accelerated Approval from the FDA so as to allow the agency to focus on and expedite the approval process for a medication indicated for a serious condition that fills an unmet medical need using clinical trial data that is believed to predict a genuine clinical benefit for patients with the given condition, such designations mean further ongoing clinical trials are necessary to confirm the clinical benefit of erdafitinib going forward.|Erdafitinib is an oral small molecule inhibitor of fibroblast growth factor receptors (FGFR) 1 to 4 that is used in the therapy of locally advanced, unresectable or metastatic urothelial carcinoma. Erdafitinib has been associated with a high rate of serum enzyme elevations during therapy, but has not been linked to cases of clinically apparent acute liver injury.|Erdafitinib is an orally bioavailable, pan fibroblast growth factor receptor (FGFR) inhibitor with potential antineoplastic activity. Upon oral administration, erdafitinib binds to and inhibits FGFR, which may result in the inhibition of FGFR-related signal transduction pathways and thus the inhibition of tumor cell proliferation and tumor cell death in FGFR-overexpressing tumor cells. FGFR, upregulated in many tumor cell types, is a receptor tyrosine kinase essential to tumor cell proliferation, differentiation and survival.

Basic Info

Product Name:

Erdafitinib

Other Name:

1,2-Ethanediamine,N1-(3,5-dimethoxyphenyl)-N2-(1-methylethyl)-N1-[3-(1-methyl-1H-pyrazol-4-yl)-6-quinoxalinyl]-;N1-(3,5-Dimethoxyphenyl)-N2-(1-methylethyl)-N1-[3-(1-methyl-1H-pyrazol-4-yl)-6-quinoxalinyl]-1,2-ethanediamine;Erdafitinib;JNJ 42756493;Balversa;1620332-47-9

CAS No.:

1346242-81-6

Molecular Formula:

C25H30N6O2

InChIKeys:

InChIKey=OLAHOMJCDNXHFI-UHFFFAOYSA-N

Molecular Weight:

446.54

Exact Mass:

446.54

UNII:

890E37NHMV

NCI Thesaurus Code:

C103273

ATC Code:

L - Antineoplastic and immunomodulating agents

Categories:

Digestive System Drugs

Characteristics

PSA:

77.3

XLogP3:

3.2

Density:

1.2±0.1 g/cm3

Flash Point:

354.4±31.5 °C

Refractive Index:

1.618

Water Solubility:

<1 mg/mL

Research

Class:

Pan-FGFR tyrosine kinase inhibitor (FGFR1-4); antineoplastic (ATC L01EN01)

Status:

Approved (FDA accelerated approval 2019-04-12; converted to regular approval 2024-01-19; EMA approval 2024-08)

Mechanism:

Erdafitinib is an orally bioavailable, functionally selective small-molecule inhibitor of fibroblast growth factor receptors 1-4 (FGFR1-4). It inhibits FGFR tyrosine kinase activity (IC50 1.2-5.7 nM), blocking downstream RAS-MAPK/ERK and PI3K-AKT signaling that drives proliferation and survival of tumor cells harboring activating FGFR alterations (mutations, amplifications, or fusions). Rapid lysosomal uptake contributes to prolonged inhibition of FGFR signaling.

EC50 (Fgfr1 Ic50):

1.2 nM

EC50 (Fgfr3 Ic50):

3.0 nM

EC50 (Fgfr2 Ic50):

2.5 nM

EC50 (Fgfr4 Ic50):

5.7 nM

EC50 (Vegfr2 Ic50):

36.8 nM (approximately 30-fold selectivity vs FGFR1)

Source:

Perera TPS, et al. Mol Cancer Ther. 2017;16(6):1010-1020.DOI

Clinical Development:

NCT02365597; NCT03390504

FDA:

Balversa (approved 2019-04-12)

References

ChEMBL:

DrugBank:

KEGG DRUG:

PubChem:

Literature:

FDA: Approval announcement 2024-01-19; FDA: BALVERSA label (NDA 212018, BLC2001); NEJM: Loriot et al. (2023) — THOR Cohort 1; NEJM: Loriot et al. (2019) — BLC2001; Mol Cancer Ther: Perera et al. (2017) — discovery pharmacology

Disclaimer:

Erdafitinib (Balversa) is a prescription medicine approved by the US FDA and the EMA for specific oncology indications. ECHEMI lists this product for industrial sourcing and supply-chain reference only. Product information on ECHEMI is provided for sourcing and specification reference. It is not medical advice, a clinical recommendation, or a substitute for approved therapy. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

See More Erdafitinib Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

Skin sensitization, Sub-category 1B

Serious eye damage, Category 1

Reproductive toxicity, Category 2

Specific target organ toxicity â repeated exposure, Category 1

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H302 Harmful if swallowed H317 May cause an allergic skin reaction H318 Causes serious eye damage H361 Suspected of damaging fertility or the unborn child H372 Causes damage to organs through prolonged or repeated exposure
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P272 Contaminated work clothing should not be allowed out of the workplace. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P203 Obtain, read and follow all safety instructions before use. P260 Do not breathe dust/fume/gas/mist/vapours/spray.
Response	P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P333+P317 If skin irritation or rash occurs: Get medical help. P321 Specific treatment (see ... on this label). P362+P364 Take off contaminated clothing and wash it before reuse. P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P317 Get medical help. P318 IF exposed or concerned, get medical advice. P319 Get medical help if you feel unwell.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Erdafitinib Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
peptide,Cosmetics

Location:
FLAT E19, 10/F, NO .52 HUNG TO ROAD, KWUN TONG HONG KONG

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
3 days

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
51-100

Year of Establishment:
2026

Introduction to Peptide Manufacturing Factory

Our peptide manufacturing factory is a professional, standardized and intelligent production base dedicated to the research, development and mass production of high-purity custom peptides and standard peptides. Adhering to strict pharmaceutical and biochemical production standards, we integrate independent R&D, precision production, rigorous quality testing and customized technical services, committing to providing high-quality peptide products and reliable solutions for global customers.

Equipped with advanced fully automated peptide synthesis production lines, purification systems and freeze-drying equipment, the factory supports multi-scale production ranging from milligram-level laboratory samples to kilogram-level industrial mass production. We cover mainstream synthesis technologies such as solid-phase peptide synthesis and liquid-phase peptide synthesis, and can efficiently customize various complex peptides, including long-chain peptides, cyclic peptides, modified peptides, fluorescent-labeled peptides and phosphorylated peptides. Our product portfolio widely serves biopharmaceutical research, cosmetic raw material development, food additive production, academic scientific research, diagnostic reagent preparation and other fields.

Quality control is the core of our production management. The factory has built a complete quality management system in line with ISO international standards, with independent professional testing laboratories. We adopt high-performance liquid chromatography (HPLC), mass spectrometry (MS), infrared spectroscopy and other precision testing methods to strictly monitor raw material screening, synthesis reaction, purification treatment, finished product packaging and every production link. This ensures that all peptide products feature high purity, stable properties, accurate molecular weight and low impurity content, meeting the differentiated quality requirements of scientific research experiments and industrial production.

With a professional technical team composed of senior peptide synthesis engineers and biochemical researchers, we have rich experience in solving difficult peptide synthesis problems and optimizing production processes. While guaranteeing product quality and production efficiency, we continuously optimize production processes, reduce production costs and shorten delivery cycles. In addition, we provide one-stop services including peptide design scheme optimization, technical consultation, after-sales technical support and personalized packaging, winning long-term trust and cooperative relationships with customers at home and abroad.

Sticking to the development concept of "technology innovation, quality supremacy, customer-oriented", our factory keeps upgrading production equipment and R&D capabilities, and strives to become a competitive professional peptide manufacturing supplier in the global biochemical industry.

Inquiry History

562 Inquiries

Country	Product	Purchase Quantity	Date Posted
Germany	High Quality Erdafitinib 99% powder 1346242-81-6 Erdafitinib	1 G	Aug 25, 2026
Vietnam	High Quality Erdafitinib 99% powder 1346242-81-6 Erdafitinib	1 G	Aug 18, 2026
United States	High Quality Erdafitinib 99% powder 1346242-81-6 Erdafitinib	1 G	Jul 26, 2026
Australia	High Quality Erdafitinib 99% powder 1346242-81-6 Erdafitinib	1 G	Aug 14, 2026
Poland	High Quality Erdafitinib 99% powder 1346242-81-6 Erdafitinib	1 G	Jul 28, 2026
Canada	Factory Direct Supply Erdafitinib Raw Powder 98% Purity Erdafitinib Powder 1346242-81-6	1 G	Sep 15, 2026
Canada	Best Price Pure 98% HPLC JNJ-42756493 Erdafitinib Powder CAS 1346242-81-6	500 MG	Sep 1, 2026
Canada	Best Price Pure 98% HPLC JNJ-42756493 Erdafitinib Powder CAS 1346242-81-6	500 MG	Aug 25, 2026
United Kingdom	Factory Direct Supply Erdafitinib Raw Powder 98% Purity Erdafitinib Powder 1346242-81-6	1 MT	Sep 4, 2026
United States	Factory Supply Erdafitinib CAS 1346242-81-6 99% High Purity FGFR Inhibitor API Powder	1 G	Sep 3, 2026
United States	Hot Selling ERDAFITINIB 1346242-81-6 Factory Supply Raw Materials High Qulity Wholesale price	3 MT	Jul 5, 2026
Australia	Erdafitinib	500 MG	Sep 16, 2026
Australia	Erdafitinib	1 G	Jul 18, 2026
Canada	Erdafitinib	1 G	Oct 12, 2026
Cyprus	Erdafitinib	1 G	Jul 22, 2026
Bulgaria	Erdafitinib	500 MG	Jun 18, 2026
Spain	Erdafitinib	1	Sep 14, 2026
Germany	Erdafitinib	500 MG	Jul 28, 2026
Switzerland	1g Erdafitinib raw powder >99% purity	1 G	May 22, 2026
Spain	Erdafitinib	1 G	Sep 25, 2026

Go to Page

Post an enquiry for this product

More Choices Find All Products for Sale 

Product Name	Grade / Content	Price	Supplier Name	Details
Erdafitinib 1346242-81-6 Chemical Grade	Industrial Grade/99	$45-56/MT FOB	Qingdao Orient Chemical Co.,LTD	Inquiry
ERDAFITINIB high quality	/	$1-1.3/BOU FOB	Nanjing Paron Technology Co., Ltd	Inquiry
Raw Erdafitinib API, CAS 1346242-81-6	Pharmaceutical Grade/99	$1/G FOB	PERBAVI SPRL	Inquiry
High- Quality Erdafitinib 99% powder 1346242-81-6 Erdafitinib	Pharmaceutical Grade/99.00	$1/G FOB	Jinan Million Pharmaceutical Co., Ltd	Inquiry
High purity API Erdafitinib CAS 1346242-81-6 In stock Chemicals with Preferential Price	Chemical Grade/99	$10.3-11.33/G FOB	Wuhan Pnq Int Trade Co., Ltd	Inquiry

High Purity Erdafitinib JNJ-42756493 Balversa FGFR Inhibitor Raw Powder 1G

Product Description

Seller Information