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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > TB500 for Sale > TB500, Synthetic Peptide, Tissue Repair, Anti-inflammatory, Wound Healing, Angiogenesis, Tendon Recovery, Muscle Recovery, Regenerative Peptide, Cell
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TB500, Synthetic Peptide, Tissue Repair, Anti-inflammatory, Wound Healing, Angiogenesis, Tendon Recovery, Muscle Recovery, Regenerative Peptide, Cell

TDS 36 Inquiries

Unit Price:

$81/UNIT FOB

Get Latest Price
CAS No.:

885340-08-9

Grade:

Research Grade

Content:

99%

Port:

Hongkong

Brand:

Novio

Packaging:

5 mg * 10 vials , 10 mg * 10 vials

Price valid (until):

2026-10-17

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Peptides,Cosmetic Raw Materials,Pharmaceutical Intermediates

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    WhatsApp +852 5274 8975
    TB500 is a synthetic small-molecule peptide derived from a naturally occurring active peptide. Due to its exceptional tissue repair capabilities, anti-inflammatory regulatory effects, and healing-promoting properties, it has garnered significant attention in fields such as sports recovery, tissue maintenance, and regeneration research. Unlike traditional repair agents—which often possess complex structures and limited, singular functions—TB500 features a stable structure and a broad spectrum of activity. Capable of simultaneously participating in various repair-related processes, it is regarded as a key candidate for bridging basic research and practical application. Years of extensive research have continuously revealed the multifaceted value of TB500, establishing it as a focal point in the fields of repair and regeneration.

    In terms of its mechanism of action, the core value of TB500 lies in its profound regulation of the tissue repair process. It precisely modulates the dynamic equilibrium of key cytoskeletal proteins; the cytoskeleton is a vital structure that supports cell morphology and drives cell migration and division. By optimizing this dynamic process, TB500 effectively promotes the directional migration of cells toward damaged areas and accelerates the formation of new cells and tissue reconstruction, thereby helping damaged structures regain their original function more rapidly. This mechanism enables it to actively facilitate the repair of various tissues—including muscles, tendons, ligaments, and skin—demonstrating broad-spectrum and deep-seated repair potential.

    TB500 offers unique and significant value in the realms of sports and functional recovery. High-intensity activity and repetitive loading often cause micro-injuries to muscles and connective tissues; without timely recovery, these injuries accumulate and impair overall athletic performance. TB500 accelerates the repair of damaged muscles and tendons, significantly shortening recovery times and alleviating lingering post-activity discomfort. Furthermore, it promotes local angiogenesis (the formation of new blood vessels) and improves nutrient delivery to damaged areas, ensuring an ample supply of energy and raw materials for tissue repair. Through the synergistic combination of accelerated repair, optimized blood supply, and inflammation relief, TB500 helps users return to their normal activity levels more quickly and reduces the risk of recurrent injury, making it highly favored in sports recovery contexts.

    Anti-inflammatory regulation represents another key functional aspect of TB500. While the inflammatory response following injury is a natural protective mechanism, excessive or prolonged inflammation can place a burden on tissues and impede the pace of repair. TB500 effectively mitigates excessive inflammation, helping to maintain a stable and orderly recovery environment for damaged tissues and preventing repair delays caused by inflammatory interference. This gentle yet efficient regulatory approach makes it suitable not only for recovery from acute injuries but also for maintaining optimal tissue health during routine care. By alleviating unnecessary inflammatory stress, TB500 helps tissues sustain vitality and resilience over the long term, thereby delaying functional decline.

    In the realm of tissue repair research, TB500 demonstrates a broad scope of action. Beyond muscles and tendons, it is being investigated for its role in repairing various tissues, including skin, the cornea, and the myocardium. Studies indicate that TB500 enhances the functional activity of diverse cell types, aiding damaged tissues in restoring structural integrity. For instance, research on skin repair shows that it accelerates wound closure and improves the quality of the repaired tissue; cardiovascular studies have also revealed its potential to improve local functional status. These diverse avenues of exploration underscore TB500's immense potential as a multifunctional repair molecule, extending its value far beyond the scope of athletic recovery alone.

    Regarding its application characteristics, TB500 is a small-molecule synthetic peptide offering excellent stability and broad applicability. Its structure is optimized to maintain activity within complex environments; it acts gently and is unlikely to trigger significant adverse reactions. It exhibits strong affinity for various tissues, integrating seamlessly into diverse repair processes, and can be flexibly combined with other active ingredients to meet specific research and application needs. These qualities—broad-spectrum efficacy, gentleness, and high efficiency—make it a vital tool in tissue repair and regeneration research.

    In terms of safety, TB500 is generally well-tolerated in standard research and application settings, with any reported side effects typically being mild and transient. Naturally, its performance depends on factors such as dosage, the specific application context, and the individual's physiological state; therefore, it should be used in accordance with established guidelines, avoiding the indiscriminate use of high doses. It should be noted that TB500 is currently primarily used as a research-grade substance for experimental purposes; its effects are largely derived from observations made under specific conditions, and individual responses vary. It cannot replace fundamental management practices such as scientifically structured training, adequate rest, and balanced nutrition.

    From an industry perspective, TB500 represents a research direction focused on "achieving efficient repair through natural bioactive peptides." By skillfully combining the multifunctional properties of natural bioactive peptides with the stability of synthetic peptides, it offers a highly valuable tool for research into tissue repair and regeneration. Unlike agents with single modes of action, TB500 delivers multiple benefits—including promoting repair, reducing inflammation, and stimulating angiogenesis—thereby aligning with the comprehensive demands for efficient recovery in modern medicine and sports science. As research progresses, the scope of its application continues to expand; future exploration will likely focus on areas such as combination therapies with other repair factors and validation across a wider range of tissue types.

    Overall, thanks to its unique mechanism of cytoskeleton regulation and broad-spectrum repair capabilities, TB500 demonstrates exceptional value in fields such as muscle recovery, tendon maintenance, anti-inflammatory regulation, and tissue regeneration. It is not only a molecule of significant interest in sports recovery research but also a highly promising candidate in the realm of regenerative medicine. By accelerating tissue repair, optimizing nutrient supply, and mitigating inflammatory responses, TB500 helps damaged tissues regain function and maintain optimal health. It offers a compelling option for those seeking efficient recovery and tissue maintenance, while also serving as a vital reference for the advancement of research into tissue repair and regeneration.

    Items Specifications
    Product Name TB500
    CAS Number 885340-08-9
    Appearance White or off-white lyophilized powder
    Purity 99%
    Specification Research grade, high-purity peptide powder
    Function Promotes tissue repair, anti-inflammatory, supports healing, promotes angiogenesis, aids tendon recovery
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    ECHEMI Editorial Reference
    TB 500 is a synthetically made version of TB4 that facilitates healing and recovery by helping build new blood vessels, muscle tissue fibers, blood cells, and facilitating cell migration. It acts on the muscular system and has anabolic properties. TB 500 is used primarily for race animals (horses and dogs).

    Certificates
    • TB500, Synthetic Peptide, Tissue Repair, Anti-inflammatory, Wound Healing, Angiogenesis, Tendon Recovery, Muscle Recovery, Regenerative Peptide, Cell Certificates 1 TDS

    Basic Info
    Product Name:

    TB500

    Other Name:

    TB500 fragment;L-Glutamine, N-acetyl-L-leucyl-L-lysyl-L-lysyl-L-threonyl-L-α-glutamyl-L-threonyl-;Thymosin Beta 4 Peptide Peptides Tb500 2mg/Vials 5mg/Vials;TB500 fragment acetate;TB500 Thymosin Beta 4 (TB4);Ac-LKKTETQ;Thymosin β4 TB500;TB500(Thymosin B4 AceTate) 5MG 10MG

    CAS No.:

    885340-08-9

    Molecular Formula:

    C38H68N10O14

    InChIKeys:

    ADKDNDYYIZUVCZ-HLXZCORBNA-N

    Molecular Weight:

    889.02

    EC Number:

    232-660-2

    Color/Form:

    White to Off-White

    Characteristics
    Density:

    1.281±0.06 g/cm3(Predicted)

    Boiling Point:

    1405.0±65.0 °C(Predicted)

    PKA:

    3.20±0.10(Predicted)

    Research
    Class:

    Actin-sequestering protein / 43-amino-acid peptide

    Status:

    Research compound — Not FDA approved (investigational: RGN-259 for dry eye / neurotrophic keratitis)

    Mechanism:

    A naturally occurring 43-amino-acid peptide (Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser-OH) that binds G-actin (sequesters monomeric actin), preventing F-actin polymerization. Promotes cell migration, angiogenesis, wound healing, and anti-inflammatory responses via integrin-linked kinase (ILK) and HIF-1α/VEGF pathways. TB-500 is the synthetic fragment Ac-LKKTETQ (MW ~895) often sold under this CAS.

    Activity note:

    Thymosin Beta-4 is an actin-binding protein, not a receptor agonist. Functional activity is measured by actin sequestration (Kd ~0.7–1 μM) and cell migration assays, not EC₅₀.

    Source:

    Goldstein AL, et al. Vitam Horm. 2003;66:257–296. RegeneRx RGN-259 clinical program.DOI

    Clinical Development:

    NCT02974907; NCT02600429; NCT00376974

    References
    DrugBank:

    DB04951

    PubChem:

    PubChem

    UNII:

    549LM7U24W

    Disclaimer:

    Thymosin Beta-4 (TB-500) is NOT FDA-approved for human therapeutic use. RGN-259 (Tβ4 ophthalmic solution) is an investigational drug not yet approved. TB-500 sold on research-chemical marketplaces is a synthetic fragment and is not an approved medicine. This listing is for industrial and laboratory research use only. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Peptides,Cosmetic Raw Materials,Pharmaceutical Intermediates

    Location:

    Room 1359, Room 103, Building Jia 19, Jixiang Garden, Tongzhou District, Beijing

    Year of Establishment:

    2026

  • Inquiry History
    36 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Factory price CAS 885340-08-9 L-Glutamine TB500

    1 KG Sep 26, 2023
    United States

    TB500 99% White powder Beta-4 CAS 885340-08-9 powder Custom peptides

    1000  Oct 30, 2023
    United States

    TB 500

    150 MG Apr 8, 2026
    United States

    China Origin TB500 2mg/5mg/10mg Lyophilized Powder for the Wound Repair Research

    1 G Mar 26, 2026
    United States

    TB500

    100 MG Feb 27, 2026
    Germany

    TB 500

    1 KG Feb 8, 2026
    Portugal

    Tb 500

    10 MT Aug 7, 2024
    France

    TB500

    1 KG Mar 27, 2024
    United States

    TB500

    1 G Jan 27, 2024
    Morocco

    PEPTIDES

    100 MG Sep 16, 2026
    Brazil

    TB-500

    1 G Jun 18, 2026
    Canada

    TB 500

    1 KG May 8, 2026
    United States

    TB 500

    20 G Feb 23, 2026
    Brazil

    alejandro

    300 PCS Feb 19, 2026
    United States

    TB500 10mg

    1 MT Oct 20, 2025
    United States

    Tesomorelin

    1 KG Aug 8, 2025
    Italy

    TB500

    1000 MG Dec 30, 2024
    Netherlands

    tb500

    Dec 16, 2024
    New Zealand

    TB500

    100 MG Jun 24, 2024
    Germany

    High Purity 99% Tb-500 5mg TB 500 Peptide TB500

    1 MT Oct 19, 2023
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