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Ebselen powder manufacturer CAS No.:60940-34-3 99% purity min. for supplement ingredients

Name: Ebselen powder manufacturer CAS No.:60940-34-3 99% purity min. for supplement ingredients
Brand: Myland
SKU: pr2609226476
Price: 200 USD
Availability: InStock

9 Inquiries

Unit Price:

$200-230/KG FOB

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CAS No.:

60940-34-3

Content:

99%

Port:

shanghai

Brand:

Myland

Packaging:

1kg/bag, 25kg/barrel

Sample Available:

Yes

Price valid (until):

2026-12-30

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Suzhou Myland Nutraceuticals Inc.

Company Type:

Trader

Location:

China

Payment Terms:

TT against copy of documents

Average Lead Time:

15 days

Qualification:

Main Products:

supplement

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Product Description
Seller Information
Inquiry History

Description

Product Detail

P roduct name	Ebselen
Other name	2-Phenyl-1,2-benzoselenazol-3-one; 2-Phenyl-benzo[d]isoselenazol-3-one;
CAS No.	60940-34-3
Molecular formula	C ₁₃ H ₉ NOSe
M olecular weight	274.18
P urity	99%
Appearance	Light yellow powder
Packing	1kg/bag, 25kg/barrel
Application	Dietary Supplement Raw Material

Product introduction

Ebselen is a small-molecule organoselenium compound with well-characterized redox-modulating properties. It exhibits glutathione peroxidase (GPx)-like activity and has demonstrated the ability to react with peroxides and peroxynitrite, supporting its potential role in studies of oxidative stress and cellular redox regulation. In experimental systems, Ebselen has been investigated for its antioxidant and anti-inflammatory activities, including the modulation of lipid peroxidation and several redox-sensitive enzymes and signaling pathways. Its reported biological effects also include inhibition of cyclooxygenase activity, lipoxygenase activity, and other thiol-dependent targets. Beyond its redox activity, Ebselen has been studied for potential neuroprotective effects in models of acute ischemic injury and oxidative stress. Research has also explored its antibacterial activity, including activity against multidrug-resistant Staphylococcus aureus (MRSA), as well as its interactions with viral and cellular targets. With its low molecular weight, cell permeability, and broad range of experimentally characterized biological activities, Ebselen is a versatile research compound for investigations involving oxidative stress, redox biology, inflammation, AIDS, neuroprotection, and cellular signaling.

Feature

(1) GPx-like antioxidant activity: Ebselen exhibits glutathione peroxidase (GPx)-like activity and supports the body’s antioxidant defense through peroxide reduction and cellular redox regulation.

(2) Potent Redox-Modulating activity: It reacts with peroxides and peroxynitrite, and interacts with thiol-containing proteins, contributing to the regulation of oxidative stress and lipid peroxidation.

(3) Broad biological activity: Ebselen interacts with multiple redox- and inflammation-related targets, including cyclooxygenase, lipoxygenase, and the thioredoxin reductase system, supporting a broad range of biological effects.

(4) Small molecule with high cell permeability: Its low molecular weight and cell-permeable properties support efficient access to intracellular targets and make it well suited to applications requiring cellular activity.

(5) Good solubility in organic solvents: Ebselen is soluble in commonly used organic solvents, including DMSO, ethanol, methanol, acetone, and acetonitrile, offering flexibility for formulation and preparation.

Applications

Ebselen combines glutathione peroxidase (GPx)-like activity with broad redox-regulating properties, supporting its relevance across several areas of nutritional and functional health development.

(1) Antioxidant & Healthy Aging Support
Ebselen exhibits GPx-like activity and participates in peroxide reduction and redox regulation, with relevance to oxidative stress and lipid peroxidation. These properties support its positioning in antioxidant nutrition and healthy aging, including applications related to skin health and environmental oxidative stress.
(2) Inflammation & Joint Health
Ebselen interacts with multiple pathways involved in oxidative and inflammatory processes, including cyclooxygenase, lipoxygenase, and the thioredoxin reductase system. Its combined antioxidant and inflammation-modulating activities make it relevant to nutritional approaches focused on inflammatory balance and joint health.
(3) Metabolic Health & Insulin Sensitivity
Ebselen has been identified as an inhibitor of SHIP2, a negative regulator of insulin signaling. Preclinical studies have associated SHIP2 inhibition by ebselen with enhanced Akt signaling and glucose uptake, together with improvements in insulin sensitivity and reductions in oxidative stress and inflammatory responses. These findings support continued interest in ebselen for metabolic health and glucose-regulation research.
(4) Auditory & Neurological Health
Ebselen has been investigated for its antioxidant, inflammation-modulating, and neuroprotective activities in auditory and neurological health. Research has examined its potential in noise- and drug-induced auditory injury, as well as oxidative and ischemic neuronal injury. Its auditory-health research has also progressed into clinical development, providing a broader scientific basis for continued investigation in this area.

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【Frequently Asked Questions】
【1】Q: What is your delivery time?
A: Generally 1~5 days after receiving payment.
【2】Q: Where is your shipping port?
A: Shanghai/Ningbo.
【3】Q: What is the specific form of packaging?
A: Usually our packaging is 1kg/bag and 25kg/barrel. Of course, if you have special
requirements, we will also package them according to your requirements.
【4】Q: Can your company accept customization and meet customers' specific specifications?
A: Yes, we can.
【5】Q: Can your company provide samples?
A: Yes, we can, please contact us by phone for specific sample information.

ECHEMI Editorial Reference

Ebselen is a small-molecule capsid Inhibitor of HIV-1 replication.Target:Ebselen is an organoselenium compound, as an inhibitor of HIV-1 capsid CTD dimerization. Ebselen inhibits early viral postentry events of the HIV-1 life cycle by impairing the incoming capsid uncoating process. [1] Ebselen is a non-toxic seleno-organic drug with anti-inflammatory and antioxidant properties. Ebselen is an inhibitor of inositol monophosphatase (IMPase). Ebselen permeates the blood-brain barrier and in
Ebselen is a benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase. It has a role as a neuroprotective agent, an apoptosis inducer, an anti-inflammatory drug, an antioxidant, a hepatoprotective agent, a genotoxin, a radical scavenger, an enzyme mimic, an EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor, an EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor, an EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor, an EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor, an EC 2.5.1.7 (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) inhibitor, an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor, an EC 3.5.4.1 (cytosine deaminase) inhibitor, an EC 5.1.3.2 (UDP-glucose 4-epimerase) inhibitor, a ferroptosis inhibitor, an antifungal agent, an EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor, an anticoronaviral agent, an antibacterial agent, an antineoplastic agent and an EC 3.1.3.25 (inositol-phosphate phosphatase) inhibitor.|Ebselen has been investigated for the treatment and basic science of Meniere's Disease, Type 2 Diabetes Mellitus, and Type 1 Diabetes Mellitus.|Ebselen is a organoselenium compound with anti-inflammatory, anti-oxidant and cytoprotective activity. Ebselen acts as a glutathione peroxidase mimetic and is thereby able to prevent cellular damage induced by reactive oxygen species (ROS). In addition, this agent inhibits the activity of a variety of enzymes including nitric oxide synthase (NOS), 5-lipoxygenase, cyclooxygenase, protein kinase C (PKC), NADPH oxidase and gastric H+/K+-ATPase. Furthermore, ebselen may be neuroprotective due to its ability to neutralize free radicals upon NMDA receptor activation thus, reducing lipoperoxidation mediated by glutamate-induced excitotoxicity.

Basic Info

Product Name:

Ebselen

Other Name:

1,2-Benzisoselenazol-3(2H)-one,2-phenyl-;2-Phenyl-1,2-benzisoselenazol-3(2H)-one;PZ 51;Ebselen;2-Phenyl-1,2-benzoisoselenazol-3(2H)-one;NSC 639762;Lopac E 3520;CCG-39161;DR 3305;SPI 1005;2-Phenyl-1,2-benzoselenazol-3-one;2-Phenylbenzo[d][1,2]selenazol-3(2H)-one

CAS No.:

60940-34-3

Molecular Formula:

C13H9NOSe

InChIKeys:

InChIKey=DYEFUKCXAQOFHX-UHFFFAOYSA-N

Molecular Weight:

274.18

Exact Mass:

274.18

UNII:

40X2P7DPGH

NSC Number:

757883|639762

DSSTox ID:

DTXSID7045150

NCI Thesaurus Code:

C65503

HScode:

2927000090

Categories:

Organoselenium Compounds

Characteristics

PSA:

20.3

Appearance:

Yellow to beige Crystalline Powder

Melting Point:

181-182 °C @ Solvent: Methanol

Flash Point:

197.4±24.0 °C

Water Solubility:

soluble in ethanol, methanol, acetone, acetonitrile.

Storage Conditions:

2-8°C

Collision Cross Section:

145.5 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

See More Ebselen Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 3, Oral

Acute toxicity - Category 3, Inhalation

Specific target organ toxicity â repeated exposure, Category 2

Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H301 Toxic if swallowed H331 Toxic if inhaled H373 May cause damage to organs through prolonged or repeated exposure H410 Very toxic to aquatic life with long lasting effects
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area. P260 Do not breathe dust/fume/gas/mist/vapours/spray. P273 Avoid release to the environment.
Response	P301+P316 IF SWALLOWED: Get emergency medical help immediately. P321 Specific treatment (see ... on this label). P330 Rinse mouth. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P316 Get emergency medical help immediately. P319 Get medical help if you feel unwell. P391 Collect spillage.
Storage	P405 Store locked up. P403+P233 Store in a well-ventilated place. Keep container tightly closed.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Ebselen Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
supplement

Location:
Building 3, Shenghe Innovation Center, No#68 Xinqing Road, Suzhou Industrial Park, China.

Payment Terms:
TT against copy of documents

Average lead Time:
15 days

Total Annual Revenue:
$25 million-$50 million

Total Employees:
11-50

Year of Establishment:
2013

Company Certificates
- ISO9001-2015
Myland is an innovative life sciences supplements, custom synthesis and manufacturing services company. We are FDA registered manufacturer securing human health with consistent quality, sustainable growth. We manufacture and source a vast range of nutrition supplements, pharmaceutical products, and take pride in delivering them while others cannot. We are experts in both small molecules and biological raw materials. We provide a full range of products and services to support life science research and development, with around a hundred of complex manufacturing service projects.
Our R&D resources and production facilities, analytical instruments are modern and versatile, allowing us to produce chemicals on the milligram to ton scale, and at ISO 9001 and GMP.
With chemistry & biology specialties and manufacturing services from the first idea to the finished product, from route scouting to GMP or ton scale production.
We keep central warehouse in Suzhou SIP to ensure strict QC process carrying out with only high quality product can be released. In the meantime we set up sub-warehouses in both USA and Europe to ensure the products reach our customers as quickly as possible.

Inquiry History

9 Inquiries

Country	Product	Purchase Quantity	Date Posted
United States	60940-34-3 Ebselen	1 KG	Nov 3, 2023
France	ebselen	50 G	Mar 9, 2026
Netherlands	Ebselen	1 KG	Nov 13, 2025
France	Ebselen	100 G	Sep 16, 2025
United States	Ebselen	200 MG	Dec 2, 2024
India	Ebselen	1 G	Mar 3, 2025
United States	Ebselen	1 MT	Mar 24, 2024
United States	EBSELEN	1 G	Mar 24, 2024
Netherlands	AF710B	1 KG	Sep 1, 2026

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Ebselen powder manufacturer CAS No.:60940-34-3 99% purity min. for supplement ingredients

Product Description

Seller Information