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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Lacosamide for Sale > Lacosamide CAS 175481-36-4 Functionalized Amino Acid Anticonvulsant for Partial-Onset Seizures and Neuropathic Pain fk
Lacosamide CAS 175481-36-4 Functionalized Amino Acid Anticonvulsant for Partial-Onset Seizures and Neuropathic Pain fk buy - large image1
Lacosamide CAS 175481-36-4 Functionalized Amino Acid Anticonvulsant for Partial-Onset Seizures and Neuropathic Pain fk buy - image1
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Lacosamide CAS 175481-36-4 Functionalized Amino Acid Anticonvulsant for Partial-Onset Seizures and Neuropathic Pain fk

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Unit Price:

$100-130/G FOB

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CAS No.:

175481-36-4

Grade:

Reagent Grade

Content:

99%

Port:

qingdao

Brand:

//

Packaging:

10mg, 25mg, 50mg, 100mg, 1g

Sample Available:

Yes

Price valid (until):

2026-10-25

Company Type:
Trader
Location:
China
Payment Terms:
TT against copy of documents,TT against B/L draft before shipment,100% TT in advance
Average Lead Time:
7 days
Qualification:
Main Products:

Medetomidine,Medetomidine hydrochloride,D-Lysergic Acid Methyl Ester,SR17018,Fluralaner,GS-441524

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

    —— Product Specification ——

    Parameter Specification Details
    Product Name Lacosamide (2R)-N-Benzyl-2-acetamido-3-methoxypropanamide
    CAS Number 175481-36-4 175481-36-4
    Molecular Formula C₁₃H₁₈N₂O₃ 13 carbons, 18 hydrogens, 2 nitrogens, 3 oxygens
    Molecular Weight 250.29 g/mol —
    Appearance White to off-white powder Visual inspection
    Purity ≥98.0% Determined by HPLC
    Melting Point 140 – 146°C —
    Boiling Point 536.4 ± 50.0°C (Predicted) —
    Density 1.12 ± 0.1 g/cm³ (Predicted) —
    pKa 13.86 ± 0.46 (Predicted) —
    XLogP3 0.3 —
    Solubility Soluble in DMSO, chloroform, methanol; slightly soluble in water —
    Storage Powder: -20°C (3 years), 4°C (2 years); In solvent: -80°C (6 months), -20°C (1 month) Protect from light and moisture
    Packaging 10mg, 25mg, 50mg, 100mg, 500mg Amber glass vials
    Application Research use only Epilepsy research, neuropathic pain studies


    —— Product Detail ——

    Product Overview

    Lacosamide (CAS 175481-36-4), also known as Vimpat or SPM 927, is a functionalized amino acid anticonvulsant developed by UCB Pharma for the treatment of partial-onset seizures and diabetic neuropathic pain . It appears as a white to off-white powder with the molecular formula C₁₃H₁₈N₂O₃ and a molecular weight of 250.29 g/mol .



    Packaging & Shipping

      • Research quantities: 10mg, 25mg, 50mg amber glass vials

      • Bulk quantities: 100mg, 1g, 5g amber glass bottles

      • Custom packaging available upon request

      • Not classified as hazardous material for transport under normal conditions

      • Product for research and analytical use only; not for human or veterinary use

    Shop CAS 18048-64-1 Eltrombopag Intermediate for Pharmaceutical Research  kr-Detailed Image 1

    — Company profile ——


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    Jinan Topfull Chemical Co., Ltd. is an international company rooted in China, specializing in the export of chemical products.

    Our company is committed to making every effort to provide ideal chemical products to potential customers worldwide, including but not limited to: organic/inorganic reagents, biological reagents, plant extracts, pharmaceutical intermediates, active pharmaceutical ingredients (APIs), reference standards, reference substances, peptides, and more. Meanwhile, we have established long-term and stable cooperative relationships with university laboratories and off-campus research institutions, enabling us to offer tailored product services based on customers' actual needs.

    We currently support customized services for most product categories, with supply quantities ranging from milligram (mg), gram (g) to kilogram (kg) levels, as well as wholesale. Product purity covers the full spectrum from 90% to 99.9%, providing customers with one-stop convenient services.

    To date, our products have been exported to developed countries such as the United States, Australia, Canada, Mexico, as well as EU member states including France, Germany, and many other countries and regions such as Nigeria, Ghana, Southeast Asia, and other parts of Asia. Our product quality and services have consistently received high praise.

    Looking ahead, our company will continue to serve as a bridge connecting China and the world, delivering high-quality products and services to global customers.

     

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    —— Q&A ——

    Q1: How to confirm the product quality before placing orders?
    A: By sending you available samples. Or if you have special requirements for the goods, we can prepare samples according to your requirements for confirmation.

    Q2: Can you supply free samples?
    A: Yes, we can provide a free sample, but the shipping cost will be paid by the customers. You can either pay the shipping cost or arrange a courier to collect the samples.

    Q3: How do you treat quality complaints?
    A: All our products are strictly tested by our QC and confirmed by QA; unqualified material will not be released to customers. If any quality problem is confirmed to be caused by us, we will replace the goods or refund your payment immediately.

    Q4: What is your MOQ? Is there a discount?
    A: For highvalue products, our MOQ starts from 1g and generally starts from 10g. For other lowprice products, our MOQ starts from 100g and 1kg.
    Q: Is there a discount?
    A: Yes, for larger quantities, we always support with better prices.

    Q5: How to start orders or make payments?
    A: You can send us your Purchase Order (if your company has one), or just send a simple confirmation by email or via Trade Manager. We will then send you a Proforma Invoice with our bank details for your confirmation, and you can make payment accordingly. If you have other preferred payment methods, we are open to discussion and negotiation.



    ECHEMI Editorial Reference
    White to Off-White SolidLacosamide (LCM), (SPM 927, (R)-2-acetamido-N-benzyl-3-methoxypropionamide, previously referred to as harkoseride or ADD 234037) is a member of a series of functionalized amino acids that were specifically synthesized as anticonvulsant or antiepileptic drug. It reduces the spread of seizure activity in the brain. Lacosamide appears to have a dual mode of action: selective enhancement of sodium channel inactivation and modulation of collapsin response mediator protein-2. 
    Lacosamide is a N-acyl-amino acid.|Lacosamide is a DEA Schedule V controlled substance. Substances in the DEA Schedule V have a low potential for abuse relative to substances listed in Schedule IV and consist primarily of preparations containing limited quantities of certain narcotics.|Lacosamide is a functionalized amino acid that has activity in the maximal electroshock seizure test, and is indicated for the adjunctive treatment of partial-onset seizures and diabetic neuropathic pain. Recent studies indicate that Lacosamide only affects those neurons which are depolarized or active for long periods of time, typical of neurons at the focus of an epileptic seizure, as opposed to other antiepileptic drugs such as carbamazepine or lamotrigine which slow the recovery from inactivation and reduce the ability of neurons to fire action potentials.|The physiologic effect of lacosamide is by means of Decreased Central Nervous System Disorganized Electrical Activity.|Lacosamide is an amino acid derivative with a unique anticonvulsant activity that is used in combination with other agents as therapy of partial onset seizures. Lacosamide therapy is associated with a low rate of transient serum enzyme elevations and has been linked to rare instances of clinically apparent liver injury.|Lacosamide is a functionalized amino acid compound specifically synthesized as an anticonvulsive drug to use as add-on therapy for partial-onset seizures with antinociceptive and neuroprotective activities. Lacosamide selectively enhances slow inactivation of voltage-gated sodium channels without affecting fast inactivation, thereby stabilizing hyperexcitabe neuronal membranes. Furthermore, this agent binds to collapsin response mediator protein 2 (CRMP2; DPYSL2), a cytosolic phosphoprotein expressed in most tissues. In the nervous system, CRMP2 acts as a mediator of growth cone collapse as well as modifies axon number, length, and neuronal polarity.|An acetamide derivative that acts as a blocker of VOLTAGE-GATED SODIUM CHANNELS. It is used as an anticonvulsant, for adjunctive or monotherapy, in the treatment of PARTIAL SEIZURES.

    Certificates
    • Lacosamide CAS 175481-36-4 Functionalized Amino Acid Anticonvulsant for Partial-Onset Seizures and Neuropathic Pain fk Certificates 1 TDS

    Basic Info
    Product Name:

    Lacosamide

    Other Name:

    Propanamide,2-(acetylamino)-3-methoxy-N-(phenylmethyl)-,(2R)-;Propanamide,2-(acetylamino)-3-methoxy-N-(phenylmethyl)-,(R)-;(2R)-2-(Acetylamino)-3-methoxy-N-(phenylmethyl)propanamide;Erlosamide;SPM 927;Lacosamide;ADD 243037;Harkoseride;Vimpat;(2R)-2-Acetamido-N-benzyl-3-methoxypropanamide;(R)-2-Acetamido-N-benzyl-3-methoxypropionamide;Lacoset 50;Lacoset;Lacosamide UCB

    CAS No.:

    175481-36-4

    Molecular Formula:

    C13H18N2O3

    InChIKeys:

    InChIKey=VPPJLAIAVCUEMN-GFCCVEGCSA-N

    Molecular Weight:

    250.29

    Exact Mass:

    250.29

    EC Number:

    1308068-626-2

    UNII:

    563KS2PQY5

    DEA Code Number:

    2746

    DSSTox ID:

    DTXSID1057666

    NCI Thesaurus Code:

    C83859

    ATC Code:

    N03AX18|N - Nervous system

    HScode:

    2924296000

    Characteristics
    PSA:

    67.4

    XLogP3:

    0.728

    Density:

    1.120±0.06 g/cm3(Predicted)

    Melting Point:

    142-143 °C @ Solvent: Ethyl acetate

    Boiling Point:

    536.447

    Flash Point:

    2℃

    Refractive Index:

    1.520

    Water Solubility:

    Lacosamide is a white to light yellow powder. It is sparingly soluble in water and slightly soluble in acetonitrile and ethanol.

    Storage Conditions:

    Refrigerator

    Vapor Pressure:

    1.4E-11mmHg at 25°C

    Specific rotation:

    D23 +16.0° (c = 1 in CH3OH)

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 3, Oral

    Eye irritation, Category 2

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H301 Toxic if swallowed

    H319 Causes serious eye irritation

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    Response

    P301+P316 IF SWALLOWED: Get emergency medical help immediately.

    P321 Specific treatment (see ... on this label).

    P330 Rinse mouth.

    P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Medetomidine,Medetomidine hydrochloride,D-Lysergic Acid Methyl Ester,SR17018,Fluralaner,GS-441524

    Location:

    RONGSHENG BEIYUANDAJIE 9, LICHENG DISTRICT,JINAN, SHANDONG CHINA

    Payment Terms:

    TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    7 days

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    11-50

    Year of Establishment:

    2022

    Jinan Topfull Chemical Co., Ltd. is a global chemical Industrial and focuses on advanced chemical technology. Specialized in Cosmetic materials, water treatment, fine chemicals and so on. We are looking forward to working together with the people of all circles at home and abroad to seek common development!
  • Inquiry History
    3 Inquiries
    Country Product Purchase Quantity Date Posted
    Bangladesh

    Lacosamide

    325 KG Jan 13, 2025
    Pakistan

    Lacosamide

    1 KG Nov 2, 2025
    Pakistan

    Lacosamide

    25 KG Jul 8, 2025
    Post an enquiry for this product
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