Product Overview

Bibenzyl (1,2-diphenylethane) is an organic compound with the molecular formula C₁₄H₁₄ and molecular weight of 182.26 g/mol. This white to off-white crystalline solid is a valuable intermediate in pharmaceutical, agrochemical, and material science research. The compound features two phenyl rings connected by an ethylene bridge.

Synthetic Process

• Reduction: Benzil or benzoin is reduced using hydrogenation catalysts or chemical reducing agents

• Wurtz Coupling: Benzyl halides are coupled using sodium metal

• Purification: The crude product is purified by recrystallization from suitable solvents

• Drying: The purified product is dried under vacuum

Mechanism of Action

• Structural Rigidity: The ethylene bridge provides a rigid scaffold for further functionalization

• Benzylic Reactivity: The benzylic positions can undergo radical halogenation

• Pharmaceutical Relevance: The bibenzyl scaffold is found in various biologically active natural products

Research Applications & Market Significance

• Pharmaceutical Research: Building block for drug discovery programs

• Material Science: Used in the preparation of specialty polymers and functional materials

• Organic Synthesis: Versatile intermediate for functionalized aromatic compounds

• Natural Product Synthesis: Precursor for the synthesis of bibenzyl-containing natural products

Quality Specifications

• Purity: ≥98.0% determined by GC

• Melting point: 52-54°C

• Boiling point: 284-286°C

• Loss on drying: ≤0.5%

• Storage: 2-8°C, sealed, protected from light

• Stable for 36 months when properly stored

Packaging & Shipping

• Research quantities: 25g, 100g amber glass bottles

• Bulk quantities: 500g, 1kg amber glass bottles

• Shipped at ambient temperature