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tert-Butyl 2-bromo-4-fluorobenzoate High Purity Organic Intermediate CAS 1455-42-1 Research Grade Reagent for Pharmaceutical and Organic Synthesis buy - large image1

tert-Butyl 2-bromo-4-fluorobenzoate High Purity Organic Intermediate CAS 1455-42-1 Research Grade Reagent for Pharmaceutical and Organic Synthesis

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Unit Price:

$50-55/KG FOB

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CAS No.:

1455-42-1

Grade:

Reagent Grade

Content:

99%

Port:

qingdao

Brand:

Packaging:

1g/vial, 5g/vial, 25g/vial, 100g/vial

Sample Available:

Yes

Price valid (until):

2026-10-30

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Jinan topfull chemical co.,ltd

Company Type:

Trader

Location:

China

Payment Terms:

TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

7 days

Qualification:

Main Products:

Medetomidine,Medetomidine hydrochloride,D-Lysergic Acid Methyl Ester,SR17018,Fluralaner,GS-441524

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Product Description
Seller Information

Description

—— Product Specifications ——

Shop tert-Butyl 2-bromo-4-fluorobenzoate High Purity Organic Intermediate CAS 1455-42-1 Research Grade Reagent for Pharmaceutical and Organic Synthesis-Detailed Image 1

—— Product Detail ——

- - - - Product Overview
        
        tert-Butyl 2-bromo-4-fluorobenzoate is an organic compound with the molecular formula C₁₁H₁₂BrFO₂ and molecular weight of 275.11 g/mol. This colorless to light yellow liquid is a valuable intermediate in pharmaceutical research. The compound features a tert-butyl ester protecting group that can be selectively deprotected under acidic conditions, along with a bromine atom and a fluorine atom on the aromatic ring.
        
        Synthetic Process
        
        Esterification: 2-Bromo-4-fluorobenzoic acid is esterified with tert-butyl alcohol in the presence of an acid catalyst
        
        Purification: The crude product is purified by distillation or chromatography
        
        Quality Control: The final product is analyzed to ensure ≥98.0% purity by GC
        
        Mechanism of Action
        
        Cross-Coupling Substrate: The aryl bromide enables Suzuki-Miyaura and other coupling reactions
        
        Protecting Group Chemistry: The tert-butyl ester serves as a carboxylic acid protecting group, removable under mild acidic conditions
        
        Fluorinated Building Block: The fluorine atom provides unique electronic properties and metabolic stability
        
        Research Applications & Market Significance
        
        Pharmaceutical Research: Building block for drug discovery programs requiring orthogonal protection strategies
        
        Organic Synthesis: Versatile intermediate for functionalized benzoate derivatives
        
        Peptide Synthesis: Used in the preparation of protected amino acid derivatives
        
        Material Science: Used in the preparation of specialty polymers
        
        Quality Specifications
        
        Purity: ≥98.0% determined by GC
        
        Boiling point: 145-147°C (2 mmHg)
        
        Density: 1.385 g/mL at 25°C
        
        Storage: 2-8°C, sealed, protected from light
        
        Stable for 24 months when properly stored
        
        Packaging & Shipping
        
        Research quantities: 5g, 25g amber glass vials
        
        Bulk quantities: 100g, 500g amber glass bottles
        
        Shipped at ambient temperature

— C ompany Profile ——

Jinan Topfull Chemical Co., Ltd. is an international company rooted in China, specializing in the export of chemical products.

Our company is committed to making every effort to provide ideal chemical products to potential customers worldwide, including but not limited to: organic/inorganic reagents, biological reagents, plant extracts, pharmaceutical intermediates, active pharmaceutical ingredients (APIs), reference standards, reference substances, peptides, and more. Meanwhile, we have established long-term and stable cooperative relationships with university laboratories and off-campus research institutions, enabling us to offer tailored product services based on customers' actual needs.

We currently support customized services for most product categories, with supply quantities ranging from milligram (mg), gram (g) to kilogram (kg) levels, as well as wholesale. Product purity covers the full spectrum from 90% to 99.9%, providing customers with one-stop convenient services.

To date, our products have been exported to developed countries such as the United States, Australia, Canada, Mexico, as well as EU member states including France, Germany, and many other countries and regions such as Nigeria, Ghana, Southeast Asia, and other parts of Asia. Our product quality and services have consistently received high praise.

Looking ahead, our company will continue to serve as a bridge connecting China and the world, delivering high-quality products and services to global customers.

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Shop Amberlite IR-120 Cation Exchange Resin Sodium Form CAS 9002-23-7 High Purity Strong Acid Cation Exchange Resin for Water Softening, Demineralization,-Detailed Image 4

—— Q&A ——

Q1: How to confirm the product quality before placing orders?
A: By sending you available samples. Or if you have special requirements for the goods, we can prepare samples according to your requirements for confirmation.

Q2: Can you supply free samples?
A: Yes, we can provide a free sample, but the shipping cost will be paid by the customers. You can either pay the shipping cost or arrange a courier to collect the samples.

Q3: How do you treat quality complaints?
A: All our products are strictly tested by our QC and confirmed by QA; unqualified material will not be released to customers. If any quality problem is confirmed to be caused by us, we will replace the goods or refund your payment immediately.

Q4: What is your MOQ? Is there a discount?
A: For highvalue products, our MOQ starts from 1g and generally starts from 10g. For other lowprice products, our MOQ starts from 100g and 1kg.
Q: Is there a discount?
A: Yes, for larger quantities, we always support with better prices.

Q5: How to start orders or make payments?
A: You can send us your Purchase Order (if your company has one), or just send a simple confirmation by email or via Trade Manager. We will then send you a Proforma Invoice with our bank details for your confirmation, and you can make payment accordingly. If you have other preferred payment methods, we are open to discussion and negotiation.

ECHEMI Editorial Reference

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Basic Info

Product Name:

β3,β3,β9,β9-Tetramethyl-2,4,8,10-tetraoxaspiro[5.5]undecane-3,9-diethanol

Other Name:

2,4,8,10-Tetraoxaspiro[5.5]undecane-3,9-diethanol,β3,β3,β9,β9-tetramethyl-;2,4,8,10-Tetraoxaspiro[5.5]undecane-3,9-diethanol,β,β,β′,β′-tetramethyl-;β3,β3,β9,β9-Tetramethyl-2,4,8,10-tetraoxaspiro[5.5]undecane-3,9-diethanol;3,9-Bis(1,1-dimethyl-2-hydroxyethyl)-2,4,8,10-tetraoxaspiro[5.5]undecane;Spiroglycol;3,9-Bis(2-hydroxy-1,1-dimethylethyl)-2,4,8,10-tetraoxaspiro(5.5)undecane;β,β,β′β′-Tetramethyl-3,9-(2,4,8,10-tetraoxaspiro[5.5]undecane)diethanol;2,2′-(2,4,8,10-Tetraoxaspiro[5.5]undecane-3,9-diyl)bis(2-methylpropan-1-ol);2-[3-(1-Hydroxy-2-methylpropan-2-yl)-2,4,8,10-tetraoxaspiro[5.5]undecan-9-yl]-2-methylpropan-1-ol;89744-28-5;1429293-67-3

CAS No.:

1455-42-1

Molecular Formula:

C15H28O6

InChIKeys:

InChIKey=BPZIYBJCZRUDEG-UHFFFAOYSA-N

Molecular Weight:

304.38

Exact Mass:

304.38

BRN:

1574570

EC Number:

485-230-3

DSSTox ID:

DTXSID1075434

HScode:

29329990

Categories:

Organic Reagents

Characteristics

PSA:

77.4

XLogP3:

0.6

Density:

1.16

Melting Point:

185-194 °C

Boiling Point:

434.2±40.0 °C(Predicted)

Flash Point:

216.4±27.3 °C

Refractive Index:

1.506

Vapor Pressure:

2.3E-09mmHg at 25°C

See More β3,β3,β9,β9-Tetramethyl-2,4,8,10-tetraoxaspiro[5.5]undecane-3,9-diethanol Properties 

Hazard Identification

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	No symbol.
Signal word	No signal word
Hazard statement(s)	none
Prevention	none
Response	none
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More β3,β3,β9,β9-Tetramethyl-2,4,8,10-tetraoxaspiro[5.5]undecane-3,9-diethanol Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Medetomidine,Medetomidine hydrochloride,D-Lysergic Acid Methyl Ester,SR17018,Fluralaner,GS-441524

Location:
RONGSHENG BEIYUANDAJIE 9, LICHENG DISTRICT,JINAN, SHANDONG CHINA

Payment Terms:
TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
7 days

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
11-50

Year of Establishment:
2022

Jinan Topfull Chemical Co., Ltd. is a global chemical Industrial and focuses on advanced chemical technology. Specialized in Cosmetic materials, water treatment, fine chemicals and so on. We are looking forward to working together with the people of all circles at home and abroad to seek common development!
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tert-Butyl 2-bromo-4-fluorobenzoate High Purity Organic Intermediate CAS 1455-42-1 Research Grade Reagent for Pharmaceutical and Organic Synthesis

Product Description

Seller Information