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NAD+(250mg)

129 Inquiries

Unit Price:

$10/UNIT FOB

Get Latest Price
CAS No.:

53-84-9

Grade:

Pharmaceutical Grade

Content:

99%

Port:

tianjin

Brand:

Pharma;Conutrix

Packaging:

10 vials/box

Price valid (until):

2026-11-20

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Retatrutide,Tirzepatide,Semaglutide,Cynomorium Songaricum Extract,Bull Penis Powder,Deer Penis Extract

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    . Product Overview

    Alprostadil, also known as Prostaglandin E1 (PGE1), is a high-purity synthetic bioactive prostaglandin molecule with pharmaceutical-grade specifications. Though not a traditional amino-acid peptide, it exhibits peptide-like high biological activity and precise signaling regulation, widely classified as a specialty therapeutic biomolecule. Produced via standardized synthetic processes with ≥99% HPLC purity, this stable small-molecule compound features ultra-high biological availability, consistent batch repeatability and low systemic irritation. As a potent EP receptor agonist, Alprostadil specializes in vascular dilation, microcirculation activation, smooth muscle relaxation and anti-platelet aggregation. It is extensively applied in vascular function research, peripheral circulation repair, microvascular lesion conditioning and high-end pharmaceutical raw material formulation development.

    2. Basic Specifications

    • Product Name: Alprostadil Pharmaceutical Grade
    • Full Name: Prostaglandin E1 (PGE1)
    • CAS Number: 745-65-3
    • Molecular Weight: 354.48 Da
    • Purity: ≥99.0% (HPLC)
    • Appearance: White sterile lyophilized powder
    • Solubility: Soluble in sterile water and aqueous solvent
    • Core Feature: Potent microcirculation activator & vascular smooth muscle regulator
    • Grade Standard: Pharmaceutical raw material grade, low endotoxin, heavy metal compliant
    • Storage: -20°C sealed, dry and protected from light
    • Shelf Life: 24 months under standard storage conditions

    3. Mechanism of Action

    Alprostadil exerts targeted vascular and tissue regulation by selectively binding to EP prostanoid receptors distributed on vascular smooth muscle, endothelial cells and peripheral tissues. It activates intracellular adenylate cyclase, elevates cAMP levels and reduces intracellular calcium concentration, triggering continuous vascular smooth muscle relaxation and systemic microvascular dilation. Meanwhile, it effectively inhibits platelet adhesion and aggregation, improves blood rheology, and eliminates microcirculation stasis and hypoxic damage.
    Different from common vasodilators with transient efficacy, Alprostadil delivers dual vascular protection and metabolic optimization. It repairs damaged vascular endothelial function, improves peripheral tissue oxygen and nutrient supply, blocks inflammatory cascades caused by microcirculation disorders, and achieves long-term stabilization of vascular physiological function without endocrine disturbance or drug resistance.

    4. Core Benefits & Applications

    • Microcirculation Activation: Dilates peripheral microvessels, improves blood flow velocity, relieves tissue ischemia and hypoxia, and repairs microcirculation dysfunction caused by aging and vascular sub-health.
    • Vascular Endothelial Repair: Protects vascular endothelial cells, reduces endothelial inflammatory damage, improves vascular elasticity, and delays peripheral vascular tissue degeneration.
    • Anti-Thrombotic & Blood Regulation: Inhibits abnormal platelet aggregation, optimizes blood rheological properties, and reduces the risk of microvascular stasis and occlusion.
    • Smooth Muscle Regulation: Relaxes cavernosal and peripheral smooth muscle, improves local blood perfusion, and supports physiological tissue function recovery.
    • Professional Research Use: High-purity API for vascular pharmacology, microcirculation mechanism research, endothelial repair study and pharmaceutical formulation development.

    5. Advantages of 99% Pharmaceutical-Grade Alprostadil

    • Precise EP receptor targeting: Specific binding to prostanoid receptors, accurate vascular regulation with minimal systemic side effects
    • Dual dilation & repair efficacy: Combines rapid microcirculation activation and long-term endothelial repair, superior to single-effect vasodilators
    • Small-molecule high permeability: Ultra-low molecular weight ensures fast tissue penetration and high bioavailability
    • ≥99% HPLC ultra-high purity, strict single impurity control, zero batch difference for synthetic prostaglandin biomolecule
    • Low endotoxin and ultra-low heavy metals, fully compliant with pharmaceutical raw material standards, stable activity and formulation compatibility

    6. Safety & Usage Features

    Alprostadil is a high-safety pharmaceutical biomolecule with reliable biological tolerance. It features mild physiological vascular regulation, no hormone interference, no cumulative toxicity and no drug dependence. Standard cyclic use safely optimizes microcirculation, repairs endothelial damage and improves tissue hypoxia status, suitable for long-term vascular sub-health conditioning and high-standard biomedical research applications.
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    Items Specifications






    ECHEMI Editorial Reference
    NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.
    Solid
    NAD zwitterion is a NAD. It has a role as a geroprotector. It derives from a deamido-NAD zwitterion. It is a conjugate base of a NAD(+).|A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)|Nadide is a dinucleotide of adenine and nicotinamide. It has coenzyme activity in redox reactions and also acts as a donor of ADP-ribose moieties.

    Basic Info
    Product Name:

    NAD

    Other Name:

    Adenosine 5′-(trihydrogen diphosphate),P′→5′-ester with 3-(aminocarbonyl)-1-β-D-ribofuranosylpyridinium,inner salt;Pyridinium,3-carbamoyl-1-β-D-ribofuranosyl-,hydroxide,5′→5′-ester with adenosine 5′-(trihydrogen pyrophosphate),inner salt;Adenosine 5′-(trihydrogen diphosphate),P′→5′-ester with 3-(aminocarbonyl)-1-β-D-ribofuranosylpyridinium hydroxide,inner salt;Codehydrase I;Codehydrogenase I;Coenzyme I;Diphosphopyridine nucleotide;DPN;Cozymase I;NAD;Nadide;Nicotinamide-adenine dinucleotide;Oxidized diphosphopyridine nucleotide;Adenine-nicotinamide dinucleotide;NAD+;Enzopride;β-NAD;β-Diphosphopyridine nucleotide;β-Nicotinamide adenine dinucleotide;β-NAD+;NSC 20272;CO-I;β-Nicotinamide adenine dinucleotide hydrate;30429-30-2;159929-29-0;1083039-67-1;1354693-98-3

    CAS No.:

    53-84-9

    Molecular Formula:

    C21H27N7O14P2

    InChIKeys:

    InChIKey=BAWFJGJZGIEFAR-NNYOXOHSSA-N

    Molecular Weight:

    663.43

    Exact Mass:

    663.109131

    EC Number:

    200-184-4

    NSC Number:

    757121

    DSSTox ID:

    DTXSID2045236

    NCI Thesaurus Code:

    C87339

    HScode:

    29349990

    Characteristics
    PSA:

    321

    XLogP3:

    -1.29620

    Appearance:

    White Powder

    Melting Point:

    140-142 °C (decomp)

    Water Solubility:

    soluble in water at 50mg/ml

    Storage Conditions:

    2-8°C

    Specific rotation:

    D20 -31.5° (c = 1.2 in water)

    Collision Cross Section:

    226.7 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|227.5 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|222.7 Ų [M+Na]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|223.8 Ų [M-H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|230.8 Ų [M+Na-2H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|227 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

    Hazard Identification

    Classification of the substance or mixture

    Not classified.

    GHS label elements, including precautionary statements

    Pictogram(s) No symbol.
    Signal word

    No signal word

    Hazard statement(s)

    none

    Precautionary statement(s)
    Prevention

    none

    Response

    none

    Storage

    none

    Disposal

    none

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Retatrutide,Tirzepatide,Semaglutide,Cynomorium Songaricum Extract,Bull Penis Powder,Deer Penis Extract

    Location:

    Hefei, Provincia de Anhui

    Year of Establishment:

    2026

  • Inquiry History
    129 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Nad+ Injection 500mg/1000mg 99% Purity CAS 53-84-9 USP in 1000mg vials

    1000 G Jan 12, 2024
    United Kingdom

    Top Quality 99% Purity Nicotinamide Adenine Dinucleotide Powder Nad CAS 53-84-9 Nad+

    5 G Oct 25, 2023
    United States

    holesale CAS 53-84-9 99% β-Nicotinamide adenine dinucleotide 99% white powder 99% WP

    1 KG Feb 10, 2025
    United Kingdom

    NAD+

    2 KG Mar 4, 2024
    India

    ß-Nicotinamide Adenine Dinucleotide hydrate

    1.00 KG Jan 29, 2026
    India

    Nicotinamide adenine dinucleotide

    300.00 G Jan 10, 2024
    United States

    NAD+ lyophilized powder pure Pharacuetical Grade

    500 G Apr 15, 2026
    India

    beta-Diphosphopyridine nucleotide

    100 KG Apr 16, 2024
    Philippines

    NAD+

    15 KG Aug 31, 2026
    Philippines

    NAD+

    15 KG Sep 1, 2026
    India

    Nicotinamide Adenine Dinucleotide

    25 KG Apr 7, 2025
    United States

    NAD+

    1 G Aug 7, 2026
    United States

    NAD+ 500mg / 1000mg

    100 MG Aug 7, 2026
    United States

    NAD+

    1000 MG Aug 4, 2026
    United States

    β-Nicotinamide adenine dinucleotide

    10 G Jul 16, 2026
    United States

    NAD

    10 MT Jul 9, 2026
    United States

    NAD+ 500

    10000 MG Jul 2, 2026
    Australia

    Nad

    10 MG Jun 16, 2026
    United States

    NAD

    1 MT Jun 15, 2026
    United States

    NAD+

    500 MG Jun 2, 2026
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