Acetyl Tetrapeptide-3, Capixyl/promotes hair growth improves follicle size, anti-aging, scalp care research

Description

Acetyl Tetrapeptide-3 (Chinese name: Acetyl Tetrapeptide-3, also known as eyebrow-stimulating peptide) is a synthetic cosmetic active polypeptide with CAS No. 827306-88-7, sequence Ac-Lys-Gly-His-Lys-NH₂, molecular formula C₂₂H₃₉N₉O₅ and molecular weight of approximately 509.6. It is formed by acetylation modification of four amino acids and is a popular polypeptide ingredient widely used in hair care and scalp care formulations at present. This product is high-purity (≥98%, tested by HPLC) powder with stable properties and easy formulation incorporation, mainly supplied as a cosmetic raw material. This product is a cosmetic raw material, not a drug, and cannot replace drug treatment.

Key Benefits

The core function of Acetyl Tetrapeptide-3 focuses on the supporting structures around hair follicles. It can stimulate the synthesis of extracellular matrix proteins in dermal papilla cells (such as type III collagen, laminin and fibronectin). These proteins are key components that anchor hair follicles and maintain their structural stability. By strengthening the "anchoring" structure of hair follicles, it helps improve hair retention, making hair look denser and healthier. Therefore, it is a commonly used active ingredient in anti-hair loss and hair growth care formulations.

Specifically, its functions in cosmetic formulations are as follows:
Strengthen hair follicle anchoring: Promote the synthesis of extracellular matrix proteins around hair follicles and enhance the fixation and supporting capacity of hair follicles.
Improve hair retention: Stabilize hair follicle structures to reduce hair shedding caused by loose hair follicles.
Scalp environment care: Help maintain a healthy scalp microenvironment and support a healthy hair appearance.
Good formulation stability: The acetylated small-molecule tetrapeptide has improved stability and can be easily incorporated into various hair care formulations.

Applications

Acetyl Tetrapeptide-3 is mainly applied in the cosmetics industry. It is a popular active ingredient for products such as anti-hair loss shampoos, scalp serums and hair growth care liquids, and can also be used in the development of eyebrow and eyelash care products. It can be used alone as a core functional ingredient, and is often compounded with other hair care active ingredients to form formulation solutions with synergistic effects.

Specific application scenarios include:
Anti-hair loss washing and care products: Used in washing and care products such as anti-hair loss shampoos and hair conditioners.
Scalp care serums: Used in leave-on products such as scalp essences and hair growth care liquids.
Eyebrow and eyelash care products: Used for the development of products like eyebrow care liquids and eyelash serums.
Compound formulations: Can be combined with other hair care peptides and plant extracts to create multi-effect hair care formulas.
Scientific research purposes: Can be used in in vitro research experiments related to hair follicle biology and hair structure.