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Betaine Anhydrous | CAS 107-43-7 | Supports Liver & Osmotic Balance

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Unit Price:

$500-600/MT FOB

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CAS No.:

107-43-7

Grade:

feed grade, food grade, pharma grade

Content:

98%

Port:

shanghai

Packaging:

25kg/bag /drum/ carton

Price valid (until):

2026-11-13

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PREMIUM INGREDIENT CO.,LTD

Company Type:

Manufactory

Location:

United Kingdom

Payment Terms:

TT against copy of documents,L/C

Average Lead Time:

80 days

Qualification:

Main Products:

l-lysine monohydrochloride,dl-methionine,n-acetyl-l-cysteine,l-methionine,glycine,l-cysteine hcl monohydrate

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Product Details
Seller Information
Inquiry History

Description

Basic Information

Item	Betaine Anhydrous
Product Name	Betaine Anhydrous
CAS No.	107-43-7
Appearance	White crystalline powder
Odor & Taste	Slightly sweet, odorless
Purity	≥99%
Moisture	≤1.0%
pH (1% solution)	5.0–7.0
Solubility	Easily soluble in water
Hygroscopicity	High, easy to cake
Product Grade	Food grade, Feed grade, Cosmetic grade
Main Application	Dietary supplement, food additive, cosmetic additive
Strength Positioning	High purity, anhydrous form, suitable for supplements and cosmetics

Product Overview

Betaine Anhydrous, Betaine Monohydrate and Betaine Hydrochloride are three common forms of betaine products. As a natural trimethylglycine compound, Betaine acts as a critical methyl donor and osmoprotectant in human and animal metabolism. It effectively supports liver detoxification, maintains cellular osmotic pressure balance, and improves nutrient utilization efficiency.

Betaine Anhydrous — Low hygroscopicity and excellent flowability. The most versatile grade, widely used in animal feed, food, and dietary supplements as a methyl donor and osmoprotectant.

Character

1.Three types of betaine for different formulation requirements

2.High purity crystalline powder, stable quality for large bulk orders

3.Good water solubility, easy to add into powder, tablet and capsule formulas

4.Different hygroscopicity and pH characteristics to match diversified application scenarios

5.Available for food, dietary supplement and animal feed industries

Main Functions

Shared Functions ( betaine anhydrous, monohydrate &Hcl)

Methyl Donor — Betaine is an efficient methyl donor that supports normal methylation metabolism in animals and humans.

Cellular Osmoprotection — Acts as an osmolyte to stabilize cell structure, protect cells against dehydration and environmental stress.

Growth & Performance Support (Feed) — Helps improve feed conversion rate, nutrient utilization and overall growth performance in livestock and aquaculture.

Specific Functions

Function	Betaine Anhydrous	Betaine Monohydrate	Betaine HCl
Methyl donor & osmoprotectant	✅	✅	✅
Feed conversion & growth promotion	✅	✅	✅ (feed grade)
Gastric acid support / digestion aid	—	—	✅ (98% grade)
Food additive (texture & taste modifier)	✅	✅	—

Applications

1.Animal Feed (largest market for betaine anhydrous, monohydrate &Hcl)

Betaine Anhydrous & Monohydrate: Widely used as a feed additive for livestock, poultry and aquaculture. As a methyl donor, it can partially spare methionine and choline in feed formulas. As an osmoprotectant, it helps animals cope with heat stress, osmotic stress and weaning stress, improving survival rate and growth performance.

2. Food

Betaine Anhydrous & Monohydrate: Used as a food additive to adjust water activity, improve texture and balance flavor. Applied in meat products, baked goods and beverages.

3. Dietary Supplement

Betaine Anhydrous: Used in human nutritional supplements for methylation support and healthy homocysteine maintenance.

Packaging & Storage

Packaging: 25kg food-grade bag / fiber drum, customized packaging available

Storage: Store in cool, dry, dark and ventilated warehouse, keep tightly sealed, Avoid moisture, high temperature and direct sunlight

Shelf Life: 24 months under sealed and proper storage conditions

Index	Betaine hydrochloride
Content	≧97.0%	≧98.0%	≧98.0%
Loss on drying	≤1.0%	≤0.5%	≤1.0%
Burning residue	≤1.5%	≤0.2%	≤1.0%
Heavy metal	≤0.001%	≤0.001%	≤0.001%
Arsenic	≤0.0001%	≤0.0001%	≤0.0001%
Trimethylamine residue	≤300ppm	≤300ppm	≤300ppm

ECHEMI Editorial Reference

Solid
Free-flowing, white crystals; Savoury
Glycine betaine is the amino acid betaine derived from glycine. It has a role as a fundamental metabolite. It is an amino-acid betaine and a glycine derivative. It is a conjugate base of a N,N,N-trimethylglycinium.|Betaine is a methyl group donor that functions in the normal metabolic cycle of methionine and reduces homocystinuria in patients with inborn errors of methionine metabolism. In the United States, betaine is distributed under the brand name Cystadane® by Rare Disease Therapeutics. Many reports have shown that betaine's therapeutic effectiveness is limited, and does not lower tHcy levels or prevent clinical symptoms [2].|Betaine is a Methylating Agent. The mechanism of action of betaine is as a Methylating Activity.|Betaine is a modified amino acid consisting of glycine with three methyl groups that serves as a methyl donor in several metabolic pathways and is used to treat the rare genetic causes of homocystinuria. Betaine has had only limited clinical use, but has not been linked to instances of serum enzyme elevations during therapy or to clinically apparent liver injury.|A naturally occurring compound that has been of interest for its role in osmoregulation. As a drug, betaine hydrochloride has been used as a source of hydrochloric acid in the treatment of hypochlorhydria. Betaine has also been used in the treatment of liver disorders, for hyperkalemia, for homocystinuria, and for gastrointestinal disturbances. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1341)

Basic Info

Product Name:

Betaine

Other Name:

Methanaminium,1-carboxy-N,N,N-trimethyl-,inner salt;Betaine;Methanaminium,1-carboxy-N,N,N-trimethyl-,hydroxide,inner salt;Ammonium compounds,substituted,(carboxymethyl)trimethyl-,hydroxide,inner salt;α-Earleine;Glycine,trimethylbetaine;Glycine betaine;Glycocoll betaine;Lycine;Oxyneurine;Trimethylglycine;Trimethylglycocoll;Glycylbetaine;(Carboxymethyl)trimethylammonium hydroxide inner salt;Abromine;Loramine AMB 13;Rubrine C;(Trimethylammonio)acetate;Aminocoat;N,N,N-Trimethylglycine;Aquadew AN 100;FinnStim;Betafin BCR;Greenstim;Betafin;Betafin BP;Cystadane;Betafin BP 20;Trimethylbetaine;Fencaijian;Bluestim;Auqadew AN 100;Genecare OSMS BA;Intracell;2-(Trimethylazaniumyl)acetate;Genencare OSMS BA;590-30-7;11042-12-9;24980-93-6;45631-77-4

CAS No.:

107-43-7

Molecular Formula:

C5H11NO2

InChIKeys:

InChIKey=KWIUHFFTVRNATP-UHFFFAOYSA-N

Molecular Weight:

117.14600

Exact Mass:

117.07900

EC Number:

203-490-6

UNII:

3SCV180C9W

NSC Number:

166511

DSSTox ID:

DTXSID8022666

Color/Form:

Deliquescent scales or prisms

ATC Code:

A16AA06|A - Alimentary tract and metabolism

HScode:

2923900090

Categories:

Enzyme

Characteristics

PSA:

40.13000

XLogP3:

0.5

Appearance:

Free-flowing, white crystals; Savoury

Density:

1.00 g/mL at 20ºC

Melting Point:

293 °C (decomp)

Water Solubility:

H2O: 160 g/100 mL

Storage Conditions:

2-8ºC

Vapor Pressure:

1.36X10-8 mm Hg at 25 deg C (est)

Taste:

Sweet

Henrys Law Constant:

Henry's Law constant = 6.2X10-16 atm-cu m/mol at 25 °C (est)

Dissociation Constants:

pKa = 2.38 (est)

Collision Cross Section:

121.4 Å² [M+H]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|121.6 Å² [M+H]+ [CCS Type: DT, Method: stepped-field]|135.56 Å² [M+Na]+ [CCS Type: DT, Method: stepped-field]|121.1 Å² [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|130.5 Å² [M+K]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|133.2 Å² [M+Na]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|121.1 Å² [M+H]+

Experimental Properties:

Isomerizes at the mp to methyl ester of dimethylaminoacetic acid; yields trimethylamine with concd KOH|Hydroxyl radical reaction rate constant = 1.1X10-11 cu cm/molec-sec at 25 °C (est)|pH of satd soln about 8.0 /monohydrate/

See More Betaine Properties 

Hazard Identification

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	No symbol.
Signal word	No signal word
Hazard statement(s)	none
Prevention	none
Response	none
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store below 40 deg C (104 deg F), preferably between 15 and 30 deg C (59 and 86 deg F), unless otherwise specified by the manufacturer . Protect from moisture .

See More Betaine Safety Data Sheet 

Seller Information

Business Type: Manufactory
Main Products: l-lysine monohydrochloride,dl-methionine,n-acetyl-l-cysteine,l-methionine,glycine,l-cysteine hcl monohydrate
Location: dongsheng road
Payment Terms: TT against copy of documents,L/C
Average lead Time: 80 days
Total Annual Revenue: $5 million-$10 million
Total Employees: 5-10
Year of Establishment: 2015

Premium Ingredient specializes in supplying and distributing food & feed amino acids, food additives and functional ingredients for more than a decade.

Our food additives portfolio covers phosphates, acidulants, preservatives, sweeteners, thickeners and leavening agents.

Our functional ingredients include vitamins, mineral products, botanical extracts, nutraceutical ingredients, functional fibers & bulking agents.

We serve over 100 clients across food & beverage, dietary supplement, sports nutrition, personal care, pharmaceutical and animal feed sectors, with products exported to dozens of countries worldwide. All our goods are sourced from top-tier Chinese manufacturers with proven expertise and complete management systems.

◆Amino Acids	◆ phosphates	◆ acidulants
◆ preservatives	◆ sweeteners	◆ functional fiber&bulking agent
◆ thickeners	◆ Leavening agents	◆ mineral products
◆ Botanical extracts	◆ vitamins	◆ nutritional products

Backed by over 10 years of industry experience, we provide one-stop-shop solutions combining high-grade products, prompt communication, on-time delivery and real-time market intelligence. Thanks to our long-term deep-rooted partnerships with source manufacturers, we can guarantee sufficient inventory, stable pricing and fast shipment.

Our third-party certifications include ISO9001, ISO14001, HACCP, HALAL, KOSHER, GMP, FAMI-QS and more. You can count on Premium Ingredient as your trusted global raw material supplier.

------------------------------------- Mission------------------------------------

Acting as a bridge between reliable Chinese manufacturers and global buyers, we carefully select partner factories with mature production capabilities and sound management systems. We deliver not only premium-quality raw materials, but also value-added services including market trend updates, supply chain risk alerts, product formulation consultation, consolidated sample shipment and full document support for import compliance. We timely forward overseas customers’ requirements to our partner factories to support product upgrading and achieve mutual growth.

-------------------------------------Our Quality------------------------------------

Our Quality

As a professional ingredient supplier, we do not operate manufacturing facilities. Instead, we build robust quality‑assurance workflows across our whole supply chain to safeguard consistent product performance for every shipment

Strict Supplier Due‑Diligence

Before entering any partnership, we carry out on-site factory visits and assess industry reputation, followed by multi-stage qualification reviews. We validate production qualifications, export track records, quality management systems and complete certification packages. New suppliers must pass sample evaluation, and only fully vetted top-tier factories are admitted to our approved supplier pool

Batch‑by‑batch Document Verification

For every order, we cross‑check factory‑issued test documents against agreed specifications including FCC, USP, EP, AJI, CP or your customized requirements. We will not forward documents to customers until key indicators are fully aligned with specifications. This step avoids inconsistent or mismatched documentation common in raw‑material trade.

Independent Third‑party Testing Coordination

Upon client request, we can arrange independent laboratory inspections from recognized third‑party institutions. We manage sample delivery, test protocol communication and report follow‑up to support your market compliance needs.

Quality Closure & Continuous Improvement

We keep traceable records for all delivered batches. If any quality concern arises, we act as your single point‑of‑contact to trace root causes with source factories, drive corrective actions and deliver practical resolution plans. Client feedback is systematically collected to optimize our supplier management and document‑review procedures.

We provide a comprehensive set of compliance documents to support your import and registration work. Our available documentation includes but is not limited to:

★ ISO Certification ★ Halal Certificate

★ Kosher Certificate ★ IP certificate

★ Haccp certificate ★ Allergens with Glutens

★ GRAS Statement ★ HACCP Program

★ BSE/TSE Statement ★ Certificate of Analysis

★ Country of Origin Certificate ★ Material Safety Data Sheet

★ Flow Chart (product processing) ★ Food Grade Certificate

★ Nutritional Information ★ GMO Statement

★ Specification Sheet

Inquiry History