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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Sermorelin Acetate for Sale > Synthetic Serm5 Acetate Lab-Grade Life-Science Research Raw Material 99% purity
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Synthetic Serm5 Acetate Lab-Grade Life-Science Research Raw Material 99% purity

TDS 2 Inquiries

Unit Price:

$56/UNIT FOB

Get Latest Price
CAS No.:

114466-38-5

Grade:

Pharmaceutical Grade

Content:

99.7%

Port:

Chinese mainland

Brand:

any

Packaging:

Vial/Bottle/Bag/Carton

Sample Available:

Yes

Price valid (until):

2027-12-31

Company Type:
Trader
Location:
China
Payment Terms:
TT against copy of documents,TT against B/L draft before shipment,100% TT in advance
Average Lead Time:
45 days
Qualification:
Main Products:

Semag lutide,Tirzepatide,Retatrutide,raw material,GHK-CU,TB500(Thymosin B4 AceTate)

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    Whatsapp:+852 9736 9543

                      

    If you are interested, please feel free to contact me at any time.


    Product Introduction

    Sermorelin Acetate, also known as GHRH (1‑29)‑NH2 acetate salt, is a synthetic 29‑amino‑acid peptide analog of human growth‑hormone‑releasing hormone. It retains the core functional fragment of endogenous GHRH. This compound is widely adopted for pre‑clinical laboratory research focused on pituitary‑axis signaling, growth‑hormone secretion regulation and related biological pathways. Our Sermorelin Acetate is supplied as high‑purity lyophilized white‑to‑off‑white powder. Each batch is verified by HPLC and mass‑spectrometry, complete COA documents can be provided upon buyer’s request.

    Mechanism of Action

    Sermorelin Acetate binds to GHRH receptors expressed on pituitary somatotroph cells. It activates Gs‑protein coupled downstream signaling cascades including cAMP‑PKA pathway, triggering pulsatile release of endogenous growth hormone in laboratory cell and animal models. It follows native physiological feedback regulation mechanisms instead of continuously elevating hormone levels. Research studies indicate it participates in IGF‑1 axis modulation without permanent disruption to pituitary‑hypothalamus feedback loops.

    Storage Condition

    Lyophilized powder: Store at ‑20℃ under dry sealed environment, avoid direct light. Stable for up to 36 months under proper storage. Reconstituted solution: Store at 2‑8℃, finish laboratory test within 14‑21 days. Avoid repeated freeze‑thaw cycles.

    Research Applications

    Widely used for life‑science pre‑clinical experiments: pituitary function research, growth‑hormone secretion mechanism study, IGF‑1 signal‑axis assay, body‑composition related animal model, peptide‑receptor interaction laboratory research.

    Company Profile


    We are a professional R&D-oriented high-tech enterprise deeply engaged in the research, development, production and sales of fine chemical raw materials. Our core product portfolio covers pharmaceutical raw materials, pharmaceutical intermediates, bioactive peptide components, high-purity cosmetic raw materials, and raw materials for nutritional and dietary supplements. Adhering to a production model that combines standardized mass manufacturing with customized technical support, we provide stable and reliable large-scale production services and undertake global wholesale business covering Asia, Europe, North America, Oceania and other regions.

    Our independently developed and optimized series of peptide raw materials boast outstanding and verified core physiological activities, including weight regulation and fat reduction, muscle growth promotion, blood sugar balance regulation, as well as anti-oxidation and anti-aging effects. With superior biological activity, high safety and stable efficacy, these peptide ingredients are widely adopted in scientific research experiments, formula development and industrial production in the pharmaceutical, medical beauty, daily cosmetics, and health care product industries, winning wide recognition from global clients.

    We implement strict standardized batch production management throughout the entire production process, from raw material screening, synthetic reaction, purification and refinement to finished product packaging and warehousing. Equipped with standardized production workshops, complete production equipment and mature technical processes, we own sufficient stable production capacity and long-term sustainable supply capabilities, effectively avoiding stock shortages and delivery delays for bulk orders.

    All our products undergo rigorous professional testing and verification by authoritative third-party testing institutions. Each batch of goods is accompanied by complete qualification documents, including professional test reports, purity inspection certificates, safety evaluation documents and relevant compliance certifications. Strict quality control standards ensure consistent batch stability, high product purity, zero abnormal fluctuations in key indicators, and full production traceability for every product batch.

    For bulk purchases, long-term cooperative orders and project procurement, we provide highly competitive transparent wholesale prices and flexible cooperation policies, maximizing cost advantages for our partners.

    We always adhere to the core corporate values of integrity, pragmatism, innovation and sustainable development. We continuously invest in technological innovation, process optimization and talent training, constantly upgrade our core technical strength, product quality system and after-sales service system, and strive to provide clients with high-cost-effective raw material solutions.

    We commit to supplying comprehensive, high-quality and reliable fine raw materials for the global pharmaceutical, cosmetic and nutritional health industries. In terms of procurement services, we support both conventional standardized batch wholesale purchases and flexible small-batch trial orders for laboratory research and pilot projects. Meanwhile, we are fully capable of docking and matching all technical and supply requirements for medium and large-scale industrial mass production, providing one-stop raw material supply and technical supporting services for global scientific research institutions, manufacturers and trading enterprises.


    Items Specifications

    5mg

    10mg


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    Certificates
    • Synthetic Serm5 Acetate Lab-Grade Life-Science Research Raw Material 99% purity Certificates 1 TDS

    Basic Info
    Product Name:

    Sermorelin Acetate

    CAS No.:

    114466-38-5

    Molecular Formula:

    C149H246N44O42S

    InChIKeys:

    BVLCEKWPOSAKSZ-YQMCHIOTSA-N

    Molecular Weight:

    3417.9 g/mol

    Exact Mass:

    3416.843184 g/mol

    Characteristics
    PSA:

    1510 Ų

    XLogP3:

    5.07090

    Research
    Class:

    GHRH analog (1–29 amino-terminal fragment, 29-amino-acid peptide amide)

    Status:

    FDA-approved diagnostic agent (Geref, discontinued). NOT for therapeutic use.

    Mechanism:

    A synthetic 29-amino-acid peptide (H-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH₂) identical to the amino-terminal segment of endogenous human GHRH. Sermorelin binds to the GHRH receptor (GHRHR) on anterior pituitary somatotrophs, stimulating pulsatile GH synthesis and secretion via the cAMP/PKA pathway. Unlike exogenous GH, sermorelin preserves the endogenous GH pulsatility and IGF-1 feedback loop.

    EC50 (Ghrhr Ec50):

    ~0.1–1 nM (cAMP accumulation in rat pituitary cells)

    Source:

    DrugBank: DB00010. Frohman LA, et al. Endocr Rev. 1986;7(3):223–253.DOI

    Clinical Development:

    NCT00001390; NCT00527397

    FDA:

    Geref (approved 1991-10-11)

    References
    ChEMBL:

    CHEMBL1201555

    DrugBank:

    DB00010

    KEGG DRUG:

    D08554

    PubChem:

    PubChem

    Disclaimer:

    Sermorelin was FDA-approved as a diagnostic agent (Geref) for growth hormone deficiency but has been discontinued (not for safety reasons). It is NOT approved for anti-aging, bodybuilding, or therapeutic GH replacement. This listing is for industrial and laboratory research use only. Research-chemical listings on B2B marketplaces are not interchangeable with approved medicines. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

    Hazard Identification

    Classification of the substance or mixture

    no data available

    GHS label elements, including precautionary statements

    Pictogram(s) no data available
    Signal word

    no data available

    Hazard statement(s)

    no data available

    Precautionary statement(s)
    Prevention

    no data available

    Response

    no data available

    Storage

    no data available

    Disposal

    no data available

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Semag lutide,Tirzepatide,Retatrutide,raw material,GHK-CU,TB500(Thymosin B4 AceTate)

    Location:

    Room 1002-C3973, No. 80, Yongtai Modaonan Street, Yongping Subdistrict, Baiyun District, Guangzhou City

    Payment Terms:

    TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    45 days

    Year of Establishment:

    2026

    Anymang is a US-based trading company dedicated to the global supply and formulation of high-quality cosmetic raw materials, with a core focus on peptide ingredients. Committed to bridging premium suppliers and beauty manufacturers worldwide, we deliver pure, stable, and efficacious peptides—including anti-aging, brightening, and firming peptides—alongside a full spectrum of cosmetic actives and custom formulation solutions. With rigorous quality control and compliance with US safety standards, we ensure consistent batch quality and reliable delivery. Our experienced team provides professional technical support and tailored services to help clients develop competitive skincare and personal care products. Trusted by partners across the globe, Anymang stands as your dependable partner for innovative, high-performance cosmetic raw materials and peptide formulations.

  • Inquiry History
    2 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Sermorelin acetate HGRH

    1 KG Nov 25, 2025
    South Korea

    Sermorlin Acetate

    10  Jul 25, 2025
    Post an enquiry for this product
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