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Home > Biochemical Engineering > Polypeptide > Elamipretide for Sale > Elamipretide SS-31 CAS 736992-21-5 Synthetic Peptide Research Raw Material, Factory Supply for In Vitro Laboratory Research
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Elamipretide SS-31 CAS 736992-21-5 Synthetic Peptide Research Raw Material, Factory Supply for In Vitro Laboratory Research

TDS 105 Inquiries

Unit Price:

$10-11/BOU FOB

Get Latest Price
CAS No.:

736992-21-5

Grade:

Research Grade

Content:

99%

Port:

guangdong

Brand:

OEM

Packaging:

5mg/vial 10vials/box

Price valid (until):

2026-11-13

Company Type:
Trader
Location:
Hongkong, China
Qualification:
Main Products:

Tirzepatide,Retatrutide,Semaglutide,GHK-Cu

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

    Product Overview SS-31 (Elamipretide, CAS 736992-21-5) is a synthetic tetrapeptide belonging to the Szeto-Schiller peptide family. Its peptide sequence: D-Arg-Dmt-Lys-Phe-NH₂. Dmt refers to 2,6-dimethyl-L-tyrosine. It is produced via mature solid-phase peptide synthesis (SPPS) route, followed by purification, lyophilization and strict batch inspection. The product appears as white to off-white lyophilized powder.

    This product is classified as research raw material, not finished drug. It is suitable for university laboratories, biotechnology research institutions and formulation research laboratories, used for basic bioscience research, peptide property characterization, in-vitro cell related experiments and biochemical pathway exploration. All experiments using this raw material must be operated inside laboratory environment. Any application related to human body is strictly prohibited. Buyers shall fully understand the usage limitation and bear full responsibility for all operations of this material.

    Items Specifications
    Product Name  SS-31
    CAS Number 736992-21-5
    Molecular Weight: 639.79 g/mol 639.79 g/mol


      Product Detail  


    Application Scope (Research Only) This raw material is used for laboratory basic research, peptide structural property study, mitochondrial related biological exploration, cell model in-vitro tests, biochemical interaction research and other scientific projects. It can only be applied for in-vitro laboratory tests. It cannot be used for clinical trials, human consumption or animal disease intervention.

    Packaging & Shipping Available package options: 5mg,10mg,20mg,50mg,100mg,500mg,1g. Customized packaging is acceptable according to customer requirements. We use sealed vial packing to protect product stability during transportation. Goods are properly packed to avoid damage, moisture and contamination in transit.

    Sample service is available for customer quality evaluation before bulk purchase. Lead time can be confirmed based on order quantity. We adopt professional packaging solution which meets international logistics requirements.

    Important Disclaimer This product is for laboratory scientific research only. It is NOT a pharmaceutical finished product. It shall not be used for any human-related application. The seller does not authorize any medical usage of this product. All users must comply with local laws and regulations when storing, handling and using this research raw material. The buyer shall assume all liabilities arising from improper use of this product.

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      Product Features  


    1. Mature synthesis process: Produced by solid-phase peptide synthesis technology, strict purification and lyophilization process, stable peptide property and batch consistency.
    2. Complete QC & traceability: Each batch undergoes HPLC and MS identification, COA available. HPLC spectrum and MS documents can be supplied on request. Batch sample retention for traceability.
    3. Flexible packaging & sample support: Multiple standard vial specifications available, custom packaging acceptable. Samples can be supplied for lab test and quality verification.
    4. Factory direct supply: Stable production capacity, flexible lead time, support small trial sample orders and large bulk orders. Suitable international transportation packaging.
    5. Clear usage boundary: This is research-only raw material, not finished medicine. Not for human use. Full disclaimer clarifies application scope for buyers.
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      Product Detail  


    What is SS-31?
    Elamipretide (SS-31) is a small peptide that can reach inside the mitochondria and affect mitochondrial function maintenance. Elamipretide belongs to a family of cell-penetrating peptides that target and accumulate at the inner mitochondrial membrane. Inside the mitochondria, elamipretide binds to cardiolipin, an essential component of the inner mitochondrial membrane, and restores the mitochondria.

    Given the effects of elamipretide on mitochondrial function and maintenance, treatment with elamipretide is under investigation to determine its benefits on human health. Recently, scientists have discovered at least four excellent benefits that can potentially make elamipretide a viable treatment option for a wide variety of conditions.

    In diabetes research, SS-31 can improve mitochondrial dysfunction related to diabetes and has potential value in the treatment of diabetes and its complications. For sepsis, SS-31 can reduce vascular permeability in septic rats. The protective effect is related to the inhibition of oxidative stress, providing a new strategy for clinical treatment.

    ECHEMI Editorial Reference
    Elamipretide has been used in trials studying the treatment of Leber's Hereditary Optic Neuropathy.
    Elamipretide, also known as MTP 131, is a mitochondria-targeted peptide antioxidant. Elamipretide decreases inflammation and protect against a variety of neurological illnesses. Elamipretide (SS-31) improves mitochondrial dysfunction, synaptic and memory impairment induced by lipopolysaccharide in mice. Elamipretide Promotes Mitophagosome Formation and Prevents Its Reduction Induced by Nutrient Excess in INS1 β-cells.
    Elamipretide Synthetic is a single, non-glycosylated polypeptide chain containing 4 amino acids, having a molecular mass of 640 Dalton and a Molecular formula of C32H49N9O5 .

    Certificates
    • Elamipretide SS-31 CAS 736992-21-5 Synthetic Peptide Research Raw Material, Factory Supply for In Vitro Laboratory Research Certificates 1 TDS

    Basic Info
    Product Name:

    Elamipretide

    Other Name:

    D-Arginyl-2,6-diMethyl-L-tyrosyl-L-lysyl-L-phenylalaninaMide;Elamipretide;L-Phenylalaninamide, D-arginyl-2,6-dimethyl-L-tyrosyl-L-lysyl-;Elamipretide (TFA salt);SS-31;MTP-131;BENDAVIA;Bendavia);Elamipretide (SS-31;ELAMIPRETIDE, >99%

    CAS No.:

    736992-21-5

    Molecular Formula:

    C32H49N9O5

    InChIKeys:

    SFVLTCAESLKEHH-WKAQUBQDSA-N

    Molecular Weight:

    639.79

    Exact Mass:

    639.38566570

    EC Number:

    205-858-1

    UNII:

    87GWG91S09

    DSSTox ID:

    DTXSID50471988

    Color/Form:

    White to Off-White

    Categories:

    Polypeptide

    Characteristics
    Density:

    1.34±0.1 g/cm3(Predicted)

    PKA:

    10.10±0.25(Predicted)

    Research
    Class:

    Mitochondria-targeted tetrapeptide (Szeto-Schiller peptide)

    Status:

    FDA-approved (Forzinity) — Accelerated Approval 2025

    Mechanism:

    A cell-permeable, synthetic tetrapeptide (D-Arg-Dmt-Lys-Phe-NH₂) that selectively concentrates in the inner mitochondrial membrane and reversibly binds to cardiolipin, a phospholipid essential for electron transport chain (ETC) function. By stabilizing cardiolipin, SS-31 restores mitochondrial bioenergetics, reduces cytochrome c peroxidase activity, and prevents oxidative damage in cells with impaired mitochondrial function.

    Activity note:

    SS-31 does not act via traditional receptor agonism. It binds cardiolipin with high selectivity in the inner mitochondrial membrane. Functional EC₅₀ values are context-dependent (cell type, stress model). Key electrophysiology studies report mitochondrial membrane potential restoration at nanomolar concentrations.

    Source:

    Szeto HH, et al. AAPS J. 2006;8(2):E277-E283. Birk AV, et al. J Am Soc Nephrol. 2014;25(6):1157-1169.DOI

    Clinical Development:

    NCT03098797; NCT02814097; NCT02976038; NCT03354065

    FDA:

    Forzinity (approved 2025-09-19)

    References
    ChEMBL:

    CHEMBL3833370

    DrugBank:

    DB11981

    KEGG DRUG:

    D10925

    PubChem:

    PubChem

    Disclaimer:

    Elamipretide (Forzinity) is FDA-approved under accelerated approval for Barth syndrome. This listing is for industrial and laboratory research use only. Research-chemical listings on B2B marketplaces are not interchangeable with approved medicines. Confirm CAS, specification, and regulatory pathway with the seller. It is not medical advice, a clinical recommendation, or an approved therapy description.

    Hazard Identification

    Classification of the substance or mixture

    no data available

    GHS label elements, including precautionary statements

    Pictogram(s) no data available
    Signal word

    no data available

    Hazard statement(s)

    no data available

    Precautionary statement(s)
    Prevention

    no data available

    Response

    no data available

    Storage

    no data available

    Disposal

    no data available

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Tirzepatide,Retatrutide,Semaglutide,GHK-Cu

    Location:

    RM 701, UNIT 108, 7/F, TWR B NEW MANDARIN PLAZA 14 SCIENCE MUSEUM RD TSIM SHA TSUI HONG KONG

    Year of Establishment:

    2026

  • Inquiry History
    105 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    SS-31 (Elamipretide MTP-131) CAS 736992-21-5 99% White Powder XO

    10  Oct 22, 2023
    United States

    SS-31

    500 MG Feb 20, 2026
    Philippines

    Elamipretide

    100 MG Mar 17, 2026
    Philippines

    Elamipretide / SS-31

    5 G Mar 16, 2026
    United States

    SS-31

    10 MG Oct 16, 2026
    United States

    SS31

    1 G Oct 15, 2026
    Kazakstan

    SS-31

    500 MG May 22, 2026
    Canada

    Ss31

    20 MG Oct 16, 2026
    Philippines

    SS-31

    30 MG Sep 15, 2026
    United States

    SS-31

    20 MG Aug 25, 2026
    United States

    SS31

    20 MG Aug 25, 2026
    United States

    Ss-31 Elamipretide

    1 PCS Aug 16, 2026
    Belgium

    Elamipretide SS-31

    50 MG Jun 18, 2026
    United States

    Elamipretide

    1 MG Jun 18, 2026
    United States

    Ss-31

    30 MG May 20, 2026
    United States

    SS-31

    50 MG May 19, 2026
    United States

    SS-31

    1 KG May 7, 2026
    United States

    SS-31 (elamipretide)

    450 MG May 3, 2026
    Russia

    SS-31 Elamipretide

    50 G Apr 3, 2026
    United States

    SS-31

    1 G Mar 30, 2026
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