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Home > Biochemical Engineering > Amino Acids and Derivatives > L-Phenylalanine for Sale > L-Phenylalanine | CAS 63-91-2 | Fermented Essential Amino Acid for Aspartame, Food & Dietary Supplement
L-Phenylalanine | CAS 63-91-2 | Fermented Essential Amino Acid for Aspartame, Food & Dietary Supplement buy - large image1
L-Phenylalanine | CAS 63-91-2 | Fermented Essential Amino Acid for Aspartame, Food & Dietary Supplement buy - image1
L-Phenylalanine | CAS 63-91-2 | Fermented Essential Amino Acid for Aspartame, Food & Dietary Supplement buy - image2
L-Phenylalanine | CAS 63-91-2 | Fermented Essential Amino Acid for Aspartame, Food & Dietary Supplement buy - image3

L-Phenylalanine | CAS 63-91-2 | Fermented Essential Amino Acid for Aspartame, Food & Dietary Supplement

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Unit Price:

$5-6/KG FOB

Get Latest Price
CAS No.:

63-91-2

Grade:

Food Grade

Content:

99%

Port:

shanghai

Packaging:

25kgs/drum

Price valid (until):

2026-11-16

Company Type:
Manufactory
Location:
United Kingdom
Payment Terms:
TT against copy of documents,L/C
Average Lead Time:
80 days
Qualification:
Main Products:

l-lysine monohydrochloride,dl-methionine,n-acetyl-l-cysteine,l-methionine,glycine,l-cysteine hcl monohydrate

  • Product Details

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


     Basic Information


    Item Details
    Product Name L-Phenylalanine
    CAS No. 63-91-2
    Molecular Formula C₉H₁₁NO₂
    Molecular Weight 165.19
    EINECS 200-568-1
    Appearance White crystalline powder
    Assay 98.5%~101.5%
    Production Method Microbial fermentation (E.coli)
    Grade Food Grade / Feed Grade / USP Pharma Grade

    Product Overview

    L-Phenylalanine is an essential aromatic amino acid manufactured by microbial fermentation from corn-derived glucose and corn steep liquor. After fermentation, the broth is purified via ion exchange, decolorization, crystallization and drying. It cannot be synthesized by human body and must be obtained externally. It is the key raw material for aspartame production, also widely applied in dietary supplements, functional foods, feed and pharmaceutical intermediates.


    Character

    • White crystalline powder, slight bitter taste, odorless,  Slightly soluble in water, freely soluble in formic acid,  High L-optical purity, low heavy metals,  Good thermal stability under normal processing condition,  Non-animal fermented source, clean label friendly

    Function

    Core nutritional & industrial functions of L-Phenylalanine:

    • Protein synthesis: Essential building block for body protein formation
    • Precursor biosynthesis: Metabolize into tyrosine, further produce neurotransmitters
    • Sweetener intermediate: Primary raw material for aspartame synthesis
    • Nutritional fortification: Amino acid fortifier for food, feed and nutrition formula

    Application

    1. Food Industry: Main raw material for aspartame production; fortifier in functional food & beverage
    2. Dietary Supplement: Amino acid premix, sports nutrition and wellness supplement formulations
    3. Feed Industry: Animal feed additive to enrich essential amino acids for livestock growth
    4. Pharmaceutical: Intermediate for pharmaceutical synthesis and clinical nutrition products

    Packaging & Storage

    • Packaging: 25kg kraft paper bag with inner PE liner
    • Storage: Keep sealed in cool, dry and dark place, avoid moisture and direct sunlight
    • Shelf Life: 24 months under recommended storage condition
    Items Specifications






    ECHEMI Editorial Reference
    L-Phenylalanine is an antagonist at α2δ calcium channels with a Ki of 980 nM. IC50 Value: 980 nM [1]Target: Calcium ChannelL-Phenylalanine (LPA) is an electrically neutral amino acid, one of the twenty common amino acids used to biochemically form proteins. In the brain, L-phenylalanine is a competitive antagonist at the glycine binding site of NMDA receptor and at the glutamate binding site of AMPA receptor [2, 3]. At the glycine binding site of NMDA receptor L-phenylalanine has an appa
    L-phenylalanine is an odorless white crystalline powder. Slightly bitter taste. pH (1% aqueous solution) 5.4 to 6. (NTP, 1992)|DryPowder|Solid|Colourless or white platelike crystals or crystalline powder; odourless
    L-phenylalanine is an odorless white crystalline powder. Slightly bitter taste. pH (1% aqueous solution) 5.4 to 6. (NTP, 1992)|L-phenylalanine is the L-enantiomer of phenylalanine. It has a role as a nutraceutical, a micronutrient, an Escherichia coli metabolite, a Saccharomyces cerevisiae metabolite, a plant metabolite, an algal metabolite, a mouse metabolite, a human xenobiotic metabolite and an EC 3.1.3.1 (alkaline phosphatase) inhibitor. It is an erythrose 4-phosphate/phosphoenolpyruvate family amino acid, a proteinogenic amino acid, a phenylalanine and a L-alpha-amino acid. It is a conjugate base of a L-phenylalaninium. It is a conjugate acid of a L-phenylalaninate. It is an enantiomer of a D-phenylalanine. It is a tautomer of a L-phenylalanine zwitterion.|Phenylalanine is an essential aromatic amino acid that is a precursor of melanin, [dopamine], [noradrenalin] (norepinephrine), and [thyroxine].|Phenylalanine is an essential aromatic amino acid in humans (provided by food), Phenylalanine plays a key role in the biosynthesis of other amino acids and is important in the structure and function of many proteins and enzymes. Phenylalanine is converted to tyrosine, used in the biosynthesis of dopamine and norepinephrine neurotransmitters. The L-form of Phenylalanine is incorporated into proteins, while the D-form acts as a painkiller. Absorption of ultraviolet radiation by Phenylalanine is used to quantify protein amounts. (NCI04)|An essential aromatic amino acid that is a precursor of MELANIN; DOPAMINE; noradrenalin (NOREPINEPHRINE), and THYROXINE.

    Basic Info
    Product Name:

    L-Phenylalanine

    Other Name:

    L-Phenylalanine;Alanine,phenyl-,L-;(S)-α-Aminohydrocinnamic acid;(S)-α-Amino-β-phenylpropionic acid;Phenylalanine;β-Phenyl-L-alanine;β-Phenyl-α-alanine;Antibiotic FN 1636;Benzenepropanoic acid,α-amino-,(S)-;Phenyl-α-alanine;3-Phenyl-L-alanine;3-Phenylalanine;(S)-Phenylalanine;(S)-α-Aminobenzenepropanoic acid;(S)-2-Amino-3-phenylpropionic acid;L-Alanine,3-phenyl-;(S)-2-Amino-3-phenylpropanoic acid;(S)-(-)-Phenylalanine;(-)-Phenylalanine;L-(-)-Phenylalanine;NSC 79477;(2S)-2-Amino-3-phenylpropanoic acid;(2s)-2-Amino-3-phenylpropanoic acid;3617-44-5;5297-02-9;10549-09-4;67675-33-6;801204-11-5;2416148-28-0

    CAS No.:

    63-91-2

    Molecular Formula:

    C9H11NO2

    InChIKeys:

    InChIKey=COLNVLDHVKWLRT-QMMMGPOBSA-N

    Molecular Weight:

    165.18900

    Exact Mass:

    165.19

    EC Number:

    200-568-1

    UNII:

    47E5O17Y3R

    DSSTox ID:

    DTXSID4040763

    NCI Thesaurus Code:

    C29601

    Color/Form:

    Prisms form water|Monoclinic plates, leaflets from warm concentrated aqueous solution; hydrated needles from dilute solutions

    HScode:

    29224995

    Characteristics
    PSA:

    63.32000

    XLogP3:

    1.34130

    Appearance:

    L-phenylalanine is an odorless white crystalline powder. Slightly bitter taste. pH (1% aqueous solution) 5.4 to 6. (NTP, 1992)

    Density:

    1.24 g/cm3

    Melting Point:

    283 °C (decomp)

    Boiling Point:

    307.5ºC at 760 mmHg

    Flash Point:

    139.8ºC

    Refractive Index:

    1.576

    Water Solubility:

    1-5 g/100 mL at 25 ºC

    Storage Conditions:

    Store at RT.

    Vapor Pressure:

    <1 Pa (25 °C)

    Specific rotation:

    Specific optical rotation: -35.1 deg at 20 °C/D (c = 1.94)

    Odor:

    Slight

    Taste:

    Bitter

    PKA:

    1.24(at 25 °C)

    Henrys Law Constant:

    Henry's Law constant = 1.2X10-10 atm-cu m/mol at 25 °C (est)

    Dissociation Constants:

    1.24 (at 25 °C)|pK1 = 1.83; pK2 = 9.13|pKa = 1.24

    Collision Cross Section:

    140.3 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|138.91 Ų [M+Na]+ [CCS Type: DT, Method: stepped-field]|146.52 Ų [M-H]- [CCS Type: DT, Method: stepped-field]|135 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine]|140.2 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|138.3 Ų [M+Na]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|139.4 Ų [M-H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|141.29 Ų [M-H]- [CCS Type: DT, Method: stepped-field]|141.28 Ų [M+H]+ [CCS Type: DT, Method: stepped-field]|140.1 Ų [M-H]-

    Experimental Properties:

    Sublimes in vacuo|Leaflets from water, decomposes at 285 °C. Specfic optical rotation: +35.0 deg at 20 °C/D (c = 2.04); +7.1 deg at 20 °C/D (c = 3.8 in 18% HCl). One gram dissolves in 35.5 mL water at 16 °C. Sparingly soluble in methanol /Phenylalanine D-form/|OCCURS IN ISOMERIC FORMS /PHENYLALANINE/

    Air and Water Reactions:

    Water soluble. Aqueous solutions are weak acids.

    Reactive Group:

    Salts, Acidic

    Reactivity Profile:

    L-PHENYLALANINE may be light sensitive. Acts as a weak acid in solution.

    Hazard Identification

    Classification of the substance or mixture

    Not classified.

    GHS label elements, including precautionary statements

    Pictogram(s) No symbol.
    Signal word

    No signal word

    Hazard statement(s)

    none

    Precautionary statement(s)
    Prevention

    none

    Response

    none

    Storage

    none

    Disposal

    none

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    l-lysine monohydrochloride,dl-methionine,n-acetyl-l-cysteine,l-methionine,glycine,l-cysteine hcl monohydrate

    Location:

    dongsheng road

    Payment Terms:

    TT against copy of documents,L/C

    Average lead Time:

    80 days

    Total Annual Revenue:

    $5 million-$10 million

    Total Employees:

    5-10

    Year of Establishment:

    2015


    Premium Ingredient specializes in supplying and distributing food & feed amino acids, food additives and functional ingredients for more than a decade. 


    Our food additives portfolio covers phosphates, acidulants, preservatives, sweeteners, thickeners and leavening agents. 


    Our functional ingredients include vitamins, mineral products, botanical extracts, nutraceutical ingredients, functional fibers & bulking agents.


    We serve over 100 clients across food & beverage, dietary supplement, sports nutrition, personal care, pharmaceutical and animal feed sectors, with products exported to dozens of countries worldwide. All our goods are sourced from top-tier Chinese manufacturers with proven expertise and complete management systems.


    ◆Amino Acids

    ◆ phosphates

    ◆ acidulants

    ◆ preservatives

    ◆ sweeteners

    ◆ functional fiber&bulking agent

    ◆ thickeners

    ◆ Leavening agents

    ◆ mineral products

    ◆ Botanical extracts

    ◆ vitamins

    ◆ nutritional products




    Backed by over 10 years of industry experience, we provide one-stop-shop solutions combining high-grade products, prompt communication, on-time delivery and real-time market intelligence. Thanks to our long-term deep-rooted partnerships with source manufacturers, we can guarantee sufficient inventory, stable pricing and fast shipment.


    Our third-party certifications include ISO9001, ISO14001, HACCP, HALAL, KOSHER, GMP, FAMI-QS and more. You can count on Premium Ingredient as your trusted global raw material supplier.



    ------------------------------------- Mission------------------------------------

     

    Acting as a bridge between reliable Chinese manufacturers and global buyers, we carefully select partner factories with mature production capabilities and sound management systems. We deliver not only premium-quality raw materials, but also value-added services including market trend updates, supply chain risk alerts, product formulation consultation, consolidated sample shipment and full document support for import compliance. We timely forward overseas customers’ requirements to our partner factories to support product upgrading and achieve mutual growth.


     




    -------------------------------------Our Quality------------------------------------




    Our Quality


    As a professional ingredient supplier, we do not operate manufacturing facilities. Instead, we build robust quality‑assurance workflows across our whole supply chain to safeguard consistent product performance for every shipment

    Strict Supplier Due‑Diligence


    Before entering any partnership, we carry out on-site factory visits and assess industry reputation, followed by multi-stage qualification reviews. We validate production qualifications, export track records, quality management systems and complete certification packages. New suppliers must pass sample evaluation, and only fully vetted top-tier factories are admitted to our approved supplier pool

    Batch‑by‑batch Document Verification


    For every order, we cross‑check factory‑issued test documents against agreed specifications including FCC, USP, EP, AJI, CP or your customized requirements. We will not forward documents to customers until key indicators are fully aligned with specifications. This step avoids inconsistent or mismatched documentation common in raw‑material trade.

    Independent Third‑party Testing Coordination


    Upon client request, we can arrange independent laboratory inspections from recognized third‑party institutions. We manage sample delivery, test protocol communication and report follow‑up to support your market compliance needs.

    Quality Closure & Continuous Improvement


    We keep traceable records for all delivered batches. If any quality concern arises, we act as your single point‑of‑contact to trace root causes with source factories, drive corrective actions and deliver practical resolution plans. Client feedback is systematically collected to optimize our supplier management and document‑review procedures.

     

     


    We provide a comprehensive set of compliance documents to support your import and registration work. Our available documentation includes but is not limited to:


    ★ ISO Certification                                         ★ Halal Certificate

    ★ Kosher Certificate                                        ★ IP certificate

    ★ Haccp certificate                                          ★ Allergens with Glutens

    ★ GRAS Statement                                          ★ HACCP Program

    ★ BSE/TSE Statement                                      ★ Certificate of Analysis

    ★ Country of Origin Certificate                        ★ Material Safety Data Sheet

    ★ Flow Chart (product processing)                   ★ Food Grade Certificate

    ★ Nutritional Information                                  ★ GMO Statement

    ★ Specification Sheet







  • Inquiry History
    7 Inquiries
    Country Product Purchase Quantity Date Posted
    United Kingdom

    L-phenylalanine 63-91-2

    200 KG Jan 29, 2024
    India

    L-Phenylalanine

    25 KG Apr 21, 2025
    Ireland

    Phenyl Alanine

    5 TON May 27, 2025
    India

    L-Phenylalanine

    1 MT Apr 23, 2025
    United Kingdom

    L-phenylalanine

    1 MT Dec 18, 2024
    Greece

    PHENYLALANINE (Phe, F)

    1000.00 KG Sep 25, 2025
    United Kingdom

    L-phenylalanine CAS 63-91-2

    200 KG Jan 26, 2024
    Post an enquiry for this product
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