TB-500(Thymosin B4 Acetate) US Warehouse Cosmetic Peptide 99% Purity Lyophilized Powder

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TB-500 is a synthetic version of a naturally occurring protein fragment called thymosin beta-4. In animal studies, it has shown potential in promoting wound healing, reducing inflammation, and aiding tissue regeneration. These findings have led some to experiment with TB-500 for human use, hoping to reap similar benefits.

1. Promotes cell migration : TB500 stimulates the movement of cells to damaged areas, which is a critical step for wound healing and tissue repair.
2. Stimulates angiogenesis: It encourages the formation of new blood vessels, which delivers more oxygen and nutrients to injured tissues, further aiding the healing process.
3. Reduces inflammation: By modulating inflammatory processes, TB500 helps to create a more favorable environment for healing to occur.
4. Supports tissue repair: It helps repair tendons, ligaments, and other soft tissues by upregulating cell-building proteins like actin, which is crucial for cell movement and structure.
5. Aids systemic recovery: Unlike some localized treatments, TB500 is thought to act systemically, supporting broader recovery functions, flexibility, and mobility.

Musculoskeletal Studies: Models of tendonitis, muscle strain, and joint injury recovery

Cardiovascular Research: Myocardial repair mechanisms post-ischemia

Dermal Repair: Evaluation of granulation tissue formation and epithelialization

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Product Name: TB500
Other Name: TB500 fragment;L-Glutamine, N-acetyl-L-leucyl-L-lysyl-L-lysyl-L-threonyl-L-α-glutamyl-L-threonyl-;Thymosin Beta 4 Peptide Peptides Tb500 2mg/Vials 5mg/Vials;TB500 fragment acetate;TB500 Thymosin Beta 4 (TB4);Ac-LKKTETQ;Thymosin β4 TB500;TB500(Thymosin B4 AceTate) 5MG 10MG
CAS No.: 885340-08-9
Molecular Formula: C38H68N10O14
InChIKeys: ADKDNDYYIZUVCZ-HLXZCORBNA-N
Molecular Weight: 889.02
EC Number: 232-660-2
Color/Form: White to Off-White
Categories: Polypeptide

Density: 1.281±0.06 g/cm3(Predicted)
Boiling Point: 1405.0±65.0 °C(Predicted)
PKA: 3.20±0.10(Predicted)

Class: Actin-sequestering protein / 43-amino-acid peptide
Status: Research compound — Not FDA approved (investigational: RGN-259 for dry eye / neurotrophic keratitis)
Mechanism: A naturally occurring 43-amino-acid peptide (Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser-OH) that binds G-actin (sequesters monomeric actin), preventing F-actin polymerization. Promotes cell migration, angiogenesis, wound healing, and anti-inflammatory responses via integrin-linked kinase (ILK) and HIF-1α/VEGF pathways. TB-500 is the synthetic fragment Ac-LKKTETQ (MW ~895) often sold under this CAS.
Activity note: Thymosin Beta-4 is an actin-binding protein, not a receptor agonist. Functional activity is measured by actin sequestration (Kd ~0.7–1 μM) and cell migration assays, not EC₅₀.

RGN-259 (Tβ4 ophthalmic solution) is an investigational drug not yet approved. TB-500 sold on research-chemical marketplaces is a synthetic fragment and is not an approved medicine. This listing is for industrial and laboratory research use only. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.