Reta reta Retatrutide 1208243-50-8 cas 2381089-83-2 30mg 15mg 10mg 99% RETA

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Retatrutide (LY3437943) acetate is a triple agonist peptide for the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R).

Retatrutide acetate inhibits human GCGR, GIPR, and GLP-1R with EC50 values of 5.79, 0.0643, and 0.775 nM, respectively. It exhibits activity on mouse GCGR, GIPR, and GLP-1R with EC50 values of 2.32, 0.191, and 0.794 nM, respectively.

In vivo, Retatrutide (LY3437943) acetate engages with GCGR and enhances glucose tolerance in an ipGTT by acting through GIP or GLP-1 receptors. Activation via the glucagon receptor by Retatrutide acetate leads to significant weight reduction and increased energy expenditure. Retatrutide acetate can be utilized in research related to obesity.

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Product Name: Retatrutide
Other Name: Retatrutide;GIPR/GLP-1R;LY3437943Retatrutide;Retalutide;Retatrutide (sodium salt);Retatrutide RT5;retatrutide 5mg;Retatratide
CAS No.: 2381089-83-2
InChIKeys: MLOLQJNKXBNWFW-SAGGEDDASA-N
Molecular Weight: 0
EC Number: 200-001-8
Color/Form: White lyophilized
Categories: Bulk Drug Intermediates

Water Solubility: Soluble in water (5mg/ml).
Storage Conditions: -20°C
Critical Temperature & Pressure: -20°C

Classification of the substance or mixture
Not classified.

GHS label elements, including precautionary statements
Pictogram(s) No symbol.
Signal word
No signal word

Hazard statement(s)
none

Precautionary statement(s)
Prevention
none

Response
none

Storage
none

Disposal
none

Other hazards which do not result in classification
no data available

Precautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.