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O-phenylenediamine 95-54-5

Name: O-phenylenediamine 95-54-5
Brand: orient
SKU: pr2610231732
Price: 45 USD
Availability: InStock

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Unit Price:

$45-56/MT FOB

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CAS No.:

95-54-5

Grade:

Industrial Grade

Content:

99%

Port:

Brand:

orient

Packaging:

1KG, 5KG, 25KG

Sample Available:

Yes

Price valid (until):

2028-04-06

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Qingdao Orient Chemical Co.,LTD

Company Type:

Trader

Location:

China

Payment Terms:

100% TT in advance

Average Lead Time:

10 days

Qualification:

Main Products:

pharmaceutical intermediates,peptides,electronic chemicals

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Product Details
Seller Information
Inquiry History

Description

Product Name:	Dermorphin
Synonyms:	DERMORPHIN ACETATE;L-Tyr-D-Ala-L-Phe-Gly-L-Tyr-L-Pro-L-Ser-NH2;Tyrosyl-alanyl-phenylalanyl-glycyl-tyrosyl-prolyl-serinamide;Dermorphin trifluoroacetate salt;Dermorphin Powder;(2S)-N-[(2S)-1-amino-3-hydroxy-1-oxopropan-2-yl]-1-[(2S)-2-[[2-[[(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-3-phenylpropanoyl]amino]acetyl]amino]-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carboxamide;Dermorphin HAc;(2S)-1-[(2S)-2-[[2-[[(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-3-phenyl-propanoyl]amino]acetyl]amino]-3-(4-hydroxyphenyl)propanoyl]-N-[(1S)-1-carbamoyl-2-hydro
CAS:	77614-16-5
MF:	C40H50N8O10
MW:	802.87
EINECS:	202-853-6
Product Categories:	77614-16-5
Mol File:	77614-16-5.mol

Dermorphin Chemical Properties

Melting point	157-159 °C
Boiling point	1323.8±65.0 °C(Predicted)
density	1.363±0.06 g/cm3(Predicted)
storage temp.	-20°C
solubility	Soluble in DMSO
form	powder
pka	9.83±0.15(Predicted)
color	white to off-white
Sequence	H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2
InChIKey	FHZPGIUBXYVUOY-VWGYHWLBSA-N
SMILES	C(N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N)(=O)[C@@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](C)NC(=O)[C@@H](N)CC1C=CC(O)=CC=1)CC1C=CC=CC=1)CC1C=CC(O)=CC=1

Safety Information

WGK Germany

MSDS Information

Dermorphin Usage And Synthesis

Structure	Dermorphin does not contain the common N-terminal sequence for the traditional endogenous peptides (Tyr–Gly–Gly–Phe), and its sequence is completely different from those of the endomorphins, which were identified as endogenous μ- peptides that also do not contain the common sequence. Interestingly, DM contains D-alanine (a D-isomer amino acid) in its sequence. The primary structure of dermorphin is YDAFGYPS-NH2.
Description	Dermorphin was first isolated from the skin of the skin of South American frogs of the genus Phyllomedusa. It is a high potency natural opiate peptide that binds selectively to mu- receptors.
Uses	A mu- receptor agonist
Definition	ChEBI: Dermorphin is an oligopeptide.
Side effects	Like μ-opiate agonists, dermorphins produce antinociception and also catalepsy, respiratory depression, constipation, tolerance, and dependence, although at a lower degree than does[1].
in vitro	Dermorphin, a peptide isolated from the skin of Phyllomedusa frogs and the peptide receptor (NOP) component by the endogenous agonist nociceptin/orphanin FQ (N/OFQ). In displacement binding studies at CHOhMu, Dermorphin and DeNo displac the binding of [3H]-DPN in a concentration dependent and saturable manner. Dermorphin displays an affinity of 7.17, while N/OFQ fails to displace [3H]-DPN at the Delta receptor. Dermorphin and DeNo stimulate the binding of GTPγ[35S] in a concentration dependent and saturable manner at the Mu receptor.
References	[1] Negri, L. P. Melchiorri and R. Lattanzi. “ and Bv8 Peptides.”Handbook of Biologically Active Peptides (Second Edition) 2013:376-383.

Q1:Do you provide sample?

A: Yes, we can provide free sample, you only need pay the shipping cost.

Q2: What is the lead time?

A: For stock goods, it usually take about 5-7 days by air, 15-30 days by sea,For customized products, the delivery time needs to be confirmed based on the actual situation.

Q3: How can I buy? What is the payment method?

A: You can contract us through Email or you can browse our website:orientchem.cc, we have bank transfer,

Q4:What if there are quality issues？

A：We attach great importance to after-sales service of our products. If there are any quality issues, please contact us within 30 days of receiving the goods and we will handle returns and exchanges for you.

ECHEMI Editorial Reference

O-phenylenediamine has active chemical properties, being able to have condensation reaction with acid, aldehydes, ketones and other compounds, generating heterocyclic compounds; it can also have oxidation, condensation, substitution and diazotization reaction.

Figure 2 is o-phenylenediamine oxidation.

Figure 3 is o-phenylenediamine condensation reaction. It appears as colorless monoclinic crystal with air and sunlight in the darker. It is slightly soluble in cold water
o-Phenylenediamine is an organic compound with the formula C6H4(NH2)2. This aromatic diamine is an important precursor to many heterocyclic compounds. It is isomeric with m-phenylenediamine and p-phenylenediamine, and is commonly referred to as OPD.
1,2-phenylenediamine appears as colorless monoclinic crystals if pure; technical grade brownish-yellow crystals or a sandy brown solid. Used in manufacture of dyes, photography, organic synthesis.|DryPowder; Liquid|BROWN-TO-YELLOW CRYSTALS. TURNS DARK ON EXPOSURE TO LIGHT.|Colorless monoclinic crystals if pure; technical grade brownish-yellow crystals or a sandy brown solid.
1,2-phenylenediamine appears as colorless monoclinic crystals if pure; technical grade brownish-yellow crystals or a sandy brown solid. Used in manufacture of dyes, photography, organic synthesis.|1,2-phenylenediamine is a phenylenediamine in which the two amino groups are ortho to each other. It has a role as a hydrogen donor. It derives from a hydride of a benzene.

Basic Info

Product Name:

o-Phenylenediamine

Other Name:

1,2-Benzenediamine;o-Phenylenediamine;C.I. 76010;C.I. Oxidation Base 16;o-Diaminobenzene;Orthamine;1,2-Diaminobenzene;1,2-Phenylenediamine;o-Benzenediamine;2-Aminoaniline;o-Aminoaniline;IK 3 (amine);o-Aminophenylamine;IK 3;NSC 5354;OPDA

CAS No.:

95-54-5

Molecular Formula:

C6H8N2

InChIKeys:

InChIKey=GEYOCULIXLDCMW-UHFFFAOYSA-N

Molecular Weight:

108.14100

Exact Mass:

108.14

EC Number:

202-430-6

UNII:

8B713N8Q0F

ICSC Number:

1441

NSC Number:

5354

UN Number:

1673

DSSTox ID:

DTXSID3025881

Color/Form:

Brownish-yellow leaflets from water; plates from chloroform|Tan crystals or leaflets from water|White crystalline solid when pure

HScode:

29215119

Categories:

Inhibitor Drugs

Characteristics

PSA:

52.04000

XLogP3:

2.01340

Appearance:

1,2-phenylenediamine appears as colorless monoclinic crystals if pure; technical grade brownish-yellow crystals or a sandy brown solid. Used in manufacture of dyes, photography, organic synthesis.

Density:

1.27

Melting Point:

103-104 °C

Boiling Point:

256-258 °C

Flash Point:

110ºC

Refractive Index:

1.66

Water Solubility:

H2O: 1 tablet/10 mL, clear, colorless

Storage Conditions:

2-8ºC

Vapor Pressure:

0.01 mm Hg ( 25 °C)

Vapor Density:

3.7 (vs air)

Toxicity:

LD50 in rats (mg/kg): 1070 orally; 516 i.p., C. Burnett et al., J. Toxicol. Environ. Health 2, 657 (1977)

Flammability characteristics:

Lower flammable limit: 1.5%

Explosive limit:

vol% in air: 1.5

Henrys Law Constant:

Henry's Law constant = 7.20X10-9 atm-cu m/mol at 25 °C (est)

Dissociation Constants:

pKa1 = less than 2; pKa2 = 4.47 at 25 °C

Collision Cross Section:

129.1 Å² [M+H]+

Experimental Properties:

Hydroxyl radical reaction rate constant = 1.76X10-10 cu cm/molec-sec at 25 °C (est)

Air and Water Reactions:

Soluble in water [Hawley]. Melting point 219 F. Flash point 277 F. Toxic by skin absorption, inhalation or ingestion. Even as a solid will spot downwind area brown/purple (Roger Patrick, DuPont Engineer).

Reactive Group:

Amines, Aromatic

Reactivity Profile:

1,2-PHENYLENEDIAMINE a weak aromatic amine base neutralizes acids in exothermic reactions to form salts. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Darkens on exposure to air (Roger Patrick, DuPont Engineer).

Flammable Limits:

Lower flammable limit: 1.5%

Physical Dangers:

Dust explosion possible if in powder or granular form, mixed with air.

See More o-Phenylenediamine Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 3, Oral

Acute toxicity - Category 4, Dermal

Eye irritation, Category 2

Skin sensitization, Category 1

Acute toxicity - Category 4, Inhalation

Germ cell mutagenicity, Category 2

Carcinogenicity, Category 2

Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H301 Toxic if swallowed H312 Harmful in contact with skin H319 Causes serious eye irritation H317 May cause an allergic skin reaction H332 Harmful if inhaled H341 Suspected of causing genetic defects H351 Suspected of causing cancer H410 Very toxic to aquatic life with long lasting effects
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P272 Contaminated work clothing should not be allowed out of the workplace. P271 Use only outdoors or in a well-ventilated area. P203 Obtain, read and follow all safety instructions before use. P273 Avoid release to the environment.
Response	P301+P316 IF SWALLOWED: Get emergency medical help immediately. P321 Specific treatment (see ... on this label). P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P317 Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P333+P317 If skin irritation or rash occurs: Get medical help. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P318 IF exposed or concerned, get medical advice. P391 Collect spillage.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

NO open flames. Closed system, dust explosion-proof electrical equipment and lighting. Prevent deposition of dust. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Separated from food and feedstuffs. Well closed.Separated from food and feedstuffs. Well closed.

See More o-Phenylenediamine Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
pharmaceutical intermediates,peptides,electronic chemicals

Location:
Room 102, 1st Floor, East Office Building, No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Zone, China (Shandong) Pilot Free Trade Zone

Payment Terms:
100% TT in advance

Average lead Time:
10 days

Total Annual Revenue:
$10 million-$25 million

Total Employees:
51-100

Year of Establishment:
2024

A reliable supplier is like insurance.

We are mainly specilized in supply of pharmaceutical intermediates, electronic chemicals，food additives, and other fine chemical products.
Integrity is the foundation, quality is life. We would like to work together with you to build a greener and brighter future.

Website: orientchem.cc
Email: scarlett@orientchem.cc
WhatsApp: +86 17753254221

Inquiry History

7 Inquiries

Country	Product	Purchase Quantity	Date Posted
Denmark	o-Phenylenediamine	500 G	Oct 23, 2026
Denmark	O-phenylenediamine	2 KG	Oct 23, 2026
Denmark	Ortho Phenylenediamine	1 KG	Oct 8, 2026
Russia	o-Phenylenediamine CAS 95-54-5	3 MT	Sep 14, 2026
Denmark	O-Phenylenediamine	1 KG	Sep 3, 2026
India	o-Phenylenediamine	20 MT	Mar 19, 2025
India	o-phenylene diamine	4 MT	Jan 8, 2024

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O-phenylenediamine 95-54-5

Product Details

Seller Information

Inquiry History

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

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