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Retatrutide LY3437943 Research Peptide 99.75% High Purity Lyophilized Powder CAS 2381089-83-2 buy - image1

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Retatrutide LY3437943 Research Peptide 99.75% High Purity Lyophilized Powder CAS 2381089-83-2

Name: Retatrutide LY3437943 Research Peptide 99.75% High Purity Lyophilized Powder CAS 2381089-83-2
Brand: Leshenghe
SKU: pr2610301566
Price: 30 USD
Availability: OutOfStock

TDS 7546 Inquiries

Unit Price:

$30/UNIT FOB

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CAS No.:

2381089-83-2

Grade:

Reagent Grade

Content:

99.9%

Port:

guangzhou

Brand:

Leshenghe

Packaging:

10vials/box 10 mg*10vials

Sample Available:

Yes

Price valid (until):

2026-11-30

 The product will be displayed normally on the website later.

Beijing Peptide Biotechnology Group

Company Type:

Trader

Location:

China

Payment Terms:

D/P,TT against B/L draft before shipment

Average Lead Time:

10 days

Qualification:

Main Products:

peptides,Retatrutide,Tirzepatide,Cosmetic peptide,API polypeptide,Pharmaceutical Peptide

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Product Details
Seller Information
Inquiry History

Description

Name: Elena

WhatsApp: +852 9017 4689

Email: 01marcusreed01@gmail.com

Welcome global customers for inquiries, samples and long-term cooperation!

Company Profile

We are a professional peptide manufacturer with an independent GMP production base and ISO 7 clean room, equipped with automated peptide synthesis, purification and lyophilization lines to ensure stable large-scale production. We have established a complete quality control system; each batch is strictly tested and a full COA is available.

The company has an experienced R&D and technical team, supports small trial orders, keeps sufficient stock, and provides fast global cold-chain delivery to ensure a stable and reliable supply chain.

Product Overview

Retatrutide is a novel long-acting GIP/GLP-1 dual receptor agonist, used for metabolic-related scientific research and basic experiments. It can act on signaling pathways related to GIP and GLP-1 receptors, providing raw material support for research on metabolic regulation, energy balance and related physiological mechanisms.

Our Retatrutide is produced in strict accordance with GMP standards using advanced solid-phase synthesis and purification processes to ensure high purity and batch consistency for global research institutions.

Item	Specification
Product Name	Retatrutide
CAS No.	2381089-83-2
Purity	≥99%
Appearance	White to off-white lyophilized powder
Form	Sterile lyophilized powder in sealed vials
Available Sizes	5mg/10mg/15mg/20mg/30mg per vial

Shop Retatrutide LY3437943 Research Peptide 99.75% High Purity Lyophilized Powder CAS 2381089-83-2-Detailed Image 3

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Quality Control & Assurance

Purity Testing: Each batch is tested by HPLC to ensure purity ≥99%, with detailed chromatograms and impurity reports provided.
Structural Verification: LC-MS technology is used to confirm molecular weight and complete peptide structure.
Safety Testing: Passes LAL endotoxin testing and microbial limit testing to ensure the product is pyrogen-free and pathogen-free.
Stability Testing: Accelerated and long-term stability studies verify the stability of purity and properties within the shelf life.
Production Traceability: Full traceability from raw materials to finished products; all production processes are completed in an ISO 7 clean environment.

Research Applications

Retatrutide is suitable for the following scientific research purposes:

Metabolic-related signaling pathway research
Energy metabolism and nutrient metabolism mechanism research
Receptor regulation and cell signal transduction research
Basic research on peptide molecular structure and activity
Preliminary R&D exploration of new bioactive raw materials

Product Characteristics & Research Value

Dual-target property, suitable for multi-pathway metabolic mechanism research.
High purity and low impurity, adaptable to various in vitro studies and model construction.
Stable molecular structure, excellent batch consistency and reliable experimental data.
Lyophilized dosage form for long-term storage and transportation with stable properties.
Applicable for research on metabolic-related molecular mechanisms, signaling pathways and biological activities.

Storage & Handling

Lyophilized powder: Store in a cool and dry place; for long-term storage, keep sealed and avoid light at -20℃.
Reconstituted solution: Refrigerate and keep away from light; use within 72 hours to maintain stability.
Other formulations: Store in a cool and dry place at room temperature, away from direct sunlight and moisture.

Core Advantages

High-purity raw materials with low impurity content, suitable for various research scenarios.
Strong batch stability, uniform properties and consistent experimental data.
Complete specifications, sufficient stock, supporting samples and bulk orders.
Factory direct supply with stable supply chain and global cold-chain delivery.
Complete COA and quality reports provided for research filing.
Customers are recommended to design their own labels; a corresponding design fee will be charged if we provide label design services.
Professional technical support including reconstitution, storage and basic experimental consultation.

Important Disclaimer

For research use only.

This product is limited to laboratory research use only and shall not be used for human, veterinary, clinical or therapeutic purposes. It has not been approved for clinical use by any regulatory authority. All operations must be carried out by qualified researchers in accordance with local laboratory safety regulations.

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Why Choose Us

We are a professional peptide manufacturer implementing strict GMP production standards and equipped with a mature quality control system.
Our product purity is tested to be ≥99%, with complete COA certificates available and stable batch performance.
We maintain sufficient in-stock inventory, provide fast global cold-chain delivery, and support small trial orders.
We have a professional R&D and technical team to offer professional guidance on product reconstitution and storage.
As a direct factory supplier, we offer competitive prices and serve as a trustworthy long-term partner.

Shop Retatrutide LY3437943 Research Peptide 99.75% High Purity Lyophilized Powder CAS 2381089-83-2-Detailed Image 9

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ECHEMI Editorial Reference

Retatrutide is a novel triple agonist peptide of the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR) and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide inhibits human GCGR, GIPR and GLP-1R with EC50 values of 5.79, 0.0643 and 0.775 nM, respectively and mouse GCGR, GIPR, and GLP-1R with EC50 values of 2.32, 0.191 and 0.794 nM, respectively. It is an important tool for obesity research.Retatrutide potently activates the GLP-1R signaling pathway to stimulate glucose-dependent insulin secretion through activity at the GIP receptor (GIPR) or the GLP-1R.Retatrutide is a synthetic peptide with glucose-lowering effects. It is an antidiabetic agent against type 2 diabetes (T2D), stimulating insulin and suppressing glucagon secretion in a glucose-dependent manner.Retatrutide was also shown to delay gastric emptying, lower fasting and postprandial glucose concentration, decrease food intake and reduce body weight in patients with type 2 diabetes.
Retatrutide (LY-3437943) was discovered by the American pharmaceutical company Eli Lilly and Company. It is a triple glucagon hormone receptor agonist (GLP-1, GIP, and GCGR receptors) for obesity. The 2024 Lasker~DeBakey Clinical Medical Research Award has been given to Joel Habener and Svetlana Mojsov for their discovery of a new hormone GLP-1(7-37) and to Lotte Knudsen for her role in developing sustained acting versions of this hormone as a treatment for obesity.

Certificates

Basic Info

Product Name:

Retatrutide

Other Name:

Retatrutide;GIPR/GLP-1R;LY3437943Retatrutide;Retalutide;Retatrutide (sodium salt);Retatrutide RT5;retatrutide 5mg;Retatratide

CAS No.:

2381089-83-2

InChIKeys:

MLOLQJNKXBNWFW-SAGGEDDASA-N

Molecular Weight:

EC Number:

200-001-8

Color/Form:

White lyophilized

Categories:

Biochemical Reagents

Characteristics

Water Solubility:

Soluble in water (5mg/ml).

Storage Conditions:

-20°C

Critical Temperature & Pressure:

-20°C

Research

Class:

Triple agonist — GCGR, GIPR, GLP-1R

Status:

Investigational (Phase 3)

Mechanism:

Simultaneously activates glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). Engineered from the native GIP backbone with amino acid substitutions to confer GCGR and GLP-1R activity.

EC50 (Human GCGR):

5.79 nM

EC50 (Mouse GIPR):

0.191 nM

EC50 (Mouse GLP1R):

0.794 nM

EC50 (Mouse GCGR):

2.32 nM

EC50 (Human GLP1R):

0.775 nM

EC50 (Human GIPR):

0.0643 nM

Source:

Jastreboff AM, et al. N Engl J Med. 2023;389(6):514-526.DOI

Clinical Development:

NCT04881760 ; NCT05882045 ; NCT06354660

References

ChEMBL:

DrugBank:

KEGG DRUG:

PubChem:

Literature:

NEJM: Jastreboff et al. (2023) — Phase 2 Trial ; FDA Drugs@FDA

Disclaimer:

Retatrutide is an investigational compound not yet approved by FDA or EMA. This listing is for industrial and laboratory research use only. Product information on ECHEMI is provided for sourcing and specification reference. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

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Seller Information

Business Type:
Trader

Main Products:
peptides,Retatrutide,Tirzepatide,Cosmetic peptide,API polypeptide,Pharmaceutical Peptide

Location:
Room 103, Building A19, Jixiangyuan, Tongzhou District, Beijing

Payment Terms:
D/P,TT against B/L draft before shipment

Average lead Time:
10 days

Total Annual Revenue:
$10 million-$25 million

Total Employees:
51-100

Year of Establishment:
2026

We are a certified manufacturer and supplier dedicated to the production and sale of cosmetic raw materials and peptides. We specialize in peptide products and are committed to delivering high quality.
"Rapid and secure delivery" is a key strength of ours. Positive customer feedback and repeat orders form the cornerstone of our mutual growth with clients.
We consistently uphold the principle of "Quality First, Customer Foremost." Our peptide products feature superior quality and advanced technology. In addition to excellent shipping services, we provide worry-free after-sales support. With over a decade of experience in the peptide industry, we operate with unwavering integrity.
We offer hundreds of peptide products to meet a wide range of customer needs. Our business spans the United States, Europe, Australia, and the rest of the world, where we maintain long-term, stable partnerships.

Inquiry History

7546 Inquiries

Country	Product	Purchase Quantity	Date Posted
United Kingdom	Retatrutide	120 MG	Nov 3, 2026
United States	Retatrutide	20 MG	Nov 3, 2026
Netherlands	retatrutide	20 MG	Nov 3, 2026
Norway	Retatrutide	100 MG	Nov 3, 2026
Australia	Retatrutide	10 MG	Nov 3, 2026
Spain	retatrutide	20 MG	Nov 3, 2026
Australia	retatrutide	30 MG	Nov 3, 2026
United States	retatrutide	10 MG	Nov 3, 2026
United States	retatrutide	20 MG	Nov 3, 2026
France	Retatrutide	20 MG	Nov 3, 2026
Israel	Retatrutide	30 MG	Nov 3, 2026
China	Retatrutide	60000 MG	Nov 3, 2026
Australia	Retatrutide	10 MG	Nov 3, 2026
Slovakia	Retatrutide	10 G	Nov 3, 2026
United Kingdom	Retatrutide	60 MG	Nov 3, 2026
United Kingdom	retatrutide	40 MG	Nov 3, 2026
United Kingdom	retatrutide	50 MG	Nov 3, 2026
United States	Retatrutide	10 MG	Nov 3, 2026
Anguilla	Retatrutide	10 MG	Nov 3, 2026
Armenia	retatrutide LY3437943	50 MG	Nov 3, 2026

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