Tripropylene glycol

192.25

192.136154

2235421

246-466-0

5U049772F7

1348

TSCA listed

DTXSID7027837

Colorless to Light yellow

29094990

58.92000

Reactivity with Water No reaction; Reactivity with Common Materials: May attack some forms of plastics and elastomers; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.

-0.83

Tripropylene glycol is a colorless liquid. (USCG, 1999)

1.021 g/mL at 25 °C (lit.)

-45°C

273 °C (lit.)

131.2±21.8 °C

n20/D1.444(lit.)

Miscible with water, methanol and ether.

<0.01 mm Hg ( 25 °C)

6.63 (vs air)

Non flammable

Characteristic.

3.0×109mol/(m3Pa) at 25℃, HSDB (2015)

1 PPM EQUIV TO 7.86 MG/CU M @ 25 °C, 760 MM HG|1 MG/L= 128 PPM|SUPERCOOLS INSTEAD OF FREEZING|Does not crystallize

Water soluble.

Alcohols and Polyols

Tripropylene glycol is a ether-alcohol derivative. The ether being relatively unreactive. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert alcohols to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides. May attack some forms of plastics [USCG, 1999].

Store at room temperature, keep dry and cool

NONH for all modes of transport

1

Xi

26-36

YK6825000

Xi: Irritant;

36/37/38

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

Special Hazards of Combustion Products: Acrid fumes of acids and aldehydes may form in fires.

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 1118 companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|Not Classified

Plastic gloves; safety glasses or face shield (USCG, 1999)

COMBUSTIBLE.|FIRE HAZARD: SLIGHT, WHEN EXPOSED TO HEAT OR FLAME; CAN REACT WITH OXIDIZING MATERIALS.

WATER, FOAM, CARBON DIOXIDE, DRY CHEMICAL.

Collect leaking and spilled liquid in sealable containers as far as possible. Wash away remainder with plenty of water.

Well closed.

A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20 °C.

NO open flames.

Use ventilation.

Protective gloves.

Wear safety spectacles.

| 0 - Materials that, under emergency conditions, would offer no hazard beyond that of ordinary combustible materials.| 1 - Materials that must be preheated before ignition can occur. Materials require considerable preheating, under all ambient temperature conditions, before ignition and combustion can occur.| 0 - Materials that in themselves are normally stable, even under fire conditions.

Tripropylene glycol was detected at unreported concentrations in the finished waters of 2 (Lake Tahoe, CA and Orange County, CA) of 16 advanced waste treatment plants in the USA(1).

Tripropylene glycol was tenatively measured (unreported concentration) in the personal air of one of 12 people during a study monitoring personal exposures to chemicals(1).

Tripropylene glycol's production and use in the manufacture of polyester polyols for urethane applications, in the manufacture of hydraulic and brake fluids, inks and some paints, and as a precursor of low molecular mass esters and polyesters(1) may result in its release to the environment through various waste streams(SRC).

Tripropylene glycol's production and use in the manufacture of polyester polyols for urethane applications, in the manufacture of hydraulic and brake fluids, inks and some paints, and as a precursor of low molecular mass esters and polyesters may result in its release to the environment through various waste streams. If released to the atmosphere, tripropylene glycol should exist in both the vapor and particulate phases based on an estimated vapor pressure of 3.2X10-4 mm Hg at 25 °C. Vapor-phase tripropylene glycol is degraded in the atmosphere by reaction with photochemically produced hydroxyl radicals with an estimated half-life of about 3 hours. Particulate-phase tripropylene glycol may be physically removed from the air by wet and dry deposition. An estimated Koc of 13 suggests that tripropylene glycol will have very high mobility in soil. By analogy to dipropylene glycol, a structurally similar compound, tripropylene glycol is expected to be resistant to biodegradation in both soil and water. Dipropylene glycol in a five day BOD test, reached 0-5% of the theoretical oxygen demand; over a four week period, only 0-3% by BOD was degraded. Tripropylene glycol is not expected to volatilize from moist soil or water surfaces based on an estimated Henry's Law constant of 3.3X10-15 atm-cu m/mole. Bioconcentration in aquatic organisms is unlikely given an estimated BCF value of 0. Exposure to tripropylene glycol may occur occupationally during its production or during its use in the manufacture of other products. (SRC)

The rate constant for the vapor-phase reaction of tripropylene glycol with photochemically produced hydroxyl radicals has been estimated as 5.6X10-11 cu cm/molecule-sec at 25 °C(SRC) using a structure estimation method(1,SRC). This corresponds to an atmospheric half-life of about 3 hours at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm(1,SRC).

An estimated BCF value of 0 was calculated for tripropylene glycol(SRC), using an estimated log Kow of -0.50(1,SRC) and a recommended regression-derived equation(2). According to a recommended classification scheme(3), this BCF value indicates that bioconcentration in aquatic organisms will not be an important fate process(SRC).

The Koc of tripropylene glycol is estimated as approximately 13(SRC), using an estimated log Kow of -0.50(1,SRC) and a regression-derived equation(2,SRC). According to a recommended classification scheme(3), this estimated Koc value suggests that tripropylene glycol has very high mobility in soil(SRC).

The Henry's Law constant for tripropylene glycol is estimated as 3.3X10-15 atm-cu m/mole(SRC) using a fragment constant estimation method(1). This value indicates that tripropylene glycol will be essentially nonvolatile from water surfaces(2,SRC). Tripropylene glycol's vapor pressure, 3.2X10-4 mm Hg(3,SRC) and Henry's Law constant(1,SRC) indicate that volatilization from dry and moist soil will not be a major fate process for this compound(SRC).

INDUSTRIAL EXPOSURE IS LIMITED ALMOST ENTIRELY TO DIRECT CONTACT WITH LIQ. VAPORS OR MISTS MAY BE ENCOUNTERED UNDER CERTAIN CONDITIONS.|NIOSH (NOES Survey 1981-1983) has statistically estimated that 74,637 workers (9,199 of these are female) are potentially exposed to tripropylene glycol in the USA(1).

...IS NOT ABSORBED THROUGH SKIN IN ACUTELY TOXIC AMT EVEN FROM PROLONGED & REPEATED CONTACT.

Non-irritating; no symptoms observed by any exposure route.

INGESTION: if large amounts are swallowed, induce vomiting; treat symptomatically. EYES or SKIN: flush with water; get medical attention if ill effects develop. (USCG, 1999)

Fresh air, rest.

Remove contaminated clothes. Rinse skin with plenty of water or shower.

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

LOW TOXICITY.|SUMMARY TOXICITY STATEMENT; ACUTE... MODERATE VIA ORAL ROUTE. MODERATE= MAY CAUSE REVERSIBLE OR IRREVERSIBLE CHANGES TO EXPOSED TISSUE, NOT PERMANENT INJURY OR DEATH. CAN CAUSE CONSIDERABLE DISCOMFORT.|NO ILL-EFFECTS ON HUMAN BEINGS HAVE BEEN REPORTED...

Mining (except oil and gas) and support activities|Propanol, [(1-methyl-1,2-ethanediyl)bis(oxy)]bis-: ACTIVE|CONTAINERS: DRUMS; TANK CARS; TANK TRUCKS.

EPA Safer Chemical Functional Use Classes -> Solvents|Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern