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Ilaprazole

Ilaprazole structure

CAS No:
172152-36-2
Formula:
C19H18N4O2S
Chemical Name:
Ilaprazole
Synonyms:
1H-Benzimidazole,2-[[(4-methoxy-3-methyl-2-pyridinyl)methyl]sulfinyl]-6-(1H-pyrrol-1-yl)-;1H-Benzimidazole,2-[[(4-methoxy-3-methyl-2-pyridinyl)methyl]sulfinyl]-5-(1H-pyrrol-1-yl)-;2-[[(4-Methoxy-3-methyl-2-pyridinyl)methyl]sulfinyl]-6-(1H-pyrrol-1-yl)-1H-benzimidazole;IY 81149;Ilaprazole;RS-ilaprazole;2-[(4-Methoxy-3-methylpyridin-2-yl)methylsulfinyl]-6-pyrrol-1-yl-1H-benzimidazole
Categories:
Active Pharmaceutical Ingredients > Digestive System Drugs

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Description

Ilaprazole (IY-81149) is a proton pump inhibitor; inhibits H+/K+-ATPase with an IC50 of 6.0 μM.

Ilaprazole is a sulfoxide and a member of benzimidazoles.|Ilaprazole has been investigated in Helicobacter Infections.

Ilaprazole Basic Attributes

Molecular Weight：

366.439

Exact Mass：

366.44

EC Number：

1308068-626-2

Characteristics

PSA：

XLogP3：

2.3

Density：

1.39

Boiling Point：

651.0±65.0 °C(Predicted)

Flash Point：

347.5±34.3 °C

Refractive Index：

1.710

Vapor Pressure：

7.87E-17mmHg at 25°C

Drug Information

MeSH Entry Terms：

ilaprazole

Computed Properties

Molecular Weight:366.4
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:366.11504700
Monoisotopic Mass:366.11504700
Topological Polar Surface Area:92
Heavy Atom Count:26
Complexity:502
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Drug Function and Efficacy

Extract from the above information

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Ilaprazole
Manufacturer	Zhuhai Free Trade Zone Lizhu Synthetic Pharmaceutical Co., Ltd.

Ilaprazole enteric-coated tablets
Ingredients	The main ingredient is ilaprazole. Chemical name: 5-(1-hydrogen-pyrrol-1-yl)-2-[[(4-methoxy-3-methyl)-2-pyridinyl]-methyl]-sulfinyl-1-hydrogen-benzimidazole.
Specifications	5 mg x 14 tablets
Manufacturer	Livzon (GROUP) Pharmaceutical FACTORY

Registered Holders

Zhejiang Hengkang Pharmaceutical Co., Ltd.

China
Active
Hunan Mingrui Pharmaceutical Co., Ltd.

China
Active
Hebei Anjian Chengyi Pharmaceutical Technology Co., Ltd.

China
Active

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