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Lidamidine

Lidamidine structure

CAS No:
66871-56-5
Formula:
C11H16N4O
Chemical Name:
Lidamidine
Synonyms:
Urea,N-(2,6-dimethylphenyl)-N′-[imino(methylamino)methyl]-;N-(2,6-Dimethylphenyl)-N′-[imino(methylamino)methyl]urea;Lidamidine;1-(2,6-Dimethylphenyl)-3-(methylamidino)urea;1-(N-Methylamidino)-3-(2,6-dimethylphenyl)urea;1-(2′,6′-Dimethylphenyl)-3-(N-methylamidino)urea;1-(2,6-Dimethylphenyl)-3-(N′-methylcarbamimidoyl)urea
Categories:
Active Pharmaceutical Ingredients > Digestive System Drugs

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Description

Lidamidine is a member of ureas.

Lidamidine Basic Attributes

Molecular Weight：

220.27

Exact Mass：

220.27

UNII：

Q8X04W8418

DSSTox ID：

DTXSID4049080

Characteristics

PSA：

77.01000

XLogP3：

2.53360

Density：

1.17g/cm3

Refractive Index：

1.578

Drug Information

MeSH：

Miscellaneous agents found useful in the symptomatic treatment of diarrhea. They have no effect on the agent(s) that cause diarrhea, but merely alleviate the condition. (See all compounds classified as Antidiarrheals.)|Drugs that bind to and activate adrenergic receptors. (See all compounds classified as Adrenergic Agonists.)

MeSH Entry Terms：

1-(2,6-dimethylphenyl)-3-methylamidinourea

Lidamidine Use and Manufacturing

High-efficiency antidiarrheal drugs, mainly to inhibit intestinal secretion, and also inhibit intestinal motility. It is used for chronic diarrhea or fulminant diarrhea caused by colitis, segmental ileitis, ulcerative colitis and ulcerative proctitis, diarrhea caused by gastrointestinal motility disorders or cancer, and diabetic diarrhea.

Computed Properties

Molecular Weight:220.27
XLogP3:1.6
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:220.13241115
Monoisotopic Mass:220.13241115
Topological Polar Surface Area:79.5
Heavy Atom Count:16
Complexity:267
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Material

Sodium hydroxide

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