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Fluvoxamine

Fluvoxamine structure

CAS No:
54739-18-3
Formula:
C15H21F3N2O2
Chemical Name:
Fluvoxamine
Synonyms:
1-Pentanone,5-methoxy-1-[4-(trifluoromethyl)phenyl]-,O-(2-aminoethyl)oxime,(1E)-;1-Pentanone,5-methoxy-1-[4-(trifluoromethyl)phenyl]-,O-(2-aminoethyl)oxime,(E)-;Fluvoxamine
Categories:
Active Pharmaceutical Ingredients > Nervous System Drugs

Description

Fluvoxamine is an antidepressant which functions pharmacologically as a selective serotonin reuptake inhibitor.Target: SSRIsFluvoxamine is effective in inhibiting 5-ht uptake by blood platelets and brain synaptosomes. The antagonism by fluvoxamine of the reserpine-induced lowering of the pentamethylenetetrazole convulsive threshold can be regarded as due to an effect upon 5-HT uptake. In contrast to the effects of desmethylimipramine and imipramine, no stimulatory effects are found in ra

Fluvoxamine Basic Attributes

Molecular Weight：

318.33

Exact Mass：

318.33

EC Number：

244-296-1

HScode：

2928000090

Characteristics

PSA：

56.84000

XLogP3：

3.11

Density：

1.2±0.1 g/cm3

Melting Point：

120-122.5°C

Boiling Point：

370.6±52.0 °C at 760 mmHg

Flash Point：

177.9±30.7 °C

Refractive Index：

1.474

Storage Conditions：

-20°C Freezer, Under Inert Atmosphere

Fluvoxamine Use and Manufacturing

A selective serotonin reuptake inhibitor (SSRI) used as an anti-depressant

Drug Function and Efficacy

Fluvoxamine maleate is a 5-hydroxytryptamine reuptake inhibitor that acts on brain nerve cells and has little effect on non-adrenergic processes. At the same time, receptor binding experiments show that fluvoxamine maleate has almost no affinity for α-adrenergic, β-adrenergic, histamine, M-cholinergic, dopaminergic or 5-hydroxytryptamine receptors.

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Fluvoxamine Maleate Tablets
Ingredients	Fluvoxamine.
Indication	1. This product should not be used in combination with monoamine oxidase inhibitors. 2. This product can slow down the decomposition rate of drugs metabolized by the liver. When used in combination with warfarin, phenytoin, theophylline and carbamazepine, it will produce obvious clinical effects. If used in combination, please adjust the doses of these drugs. 3. Fluvoxamine maleate can increase the plasma concentration of benzodiazepines metabolized by oxidation. There are reports that fluvoxamine maleate can increase the original steady-state plasma concentration of tricyclic antidepressants. It is recommended that this product should not be used simultaneously with tricyclic antidepressants. 4. This product can increase the plasma level of propranolol. It is recommended to reduce the dose of propranolol when taking it together. 5. After two weeks of co-use of this product with warfarin, the plasma concentration of warfarin increased significantly and the coagulation time was prolonged. When patients take oral anticoagulants and fluvoxamine, the coagulation time should be monitored and the fluvoxamine dose should be adjusted accordingly. 6. This product can be used in combination with lithium to treat severe, drug-resistant depressed patients. However, lithium and tryptophan may aggravate the serotonergic effect of fluvoxamine. 7. No synergistic reaction between this product and digoxin and atenolol was observed. 8. As with other psychiatric drugs, alcohol intake should be avoided during the use of fluvoxamine maleate.
Specifications	50 mg
Manufacturer	Livzon (GROUP) Pharmaceutical FACTORY

Recommended Suppliers of Fluvoxamine

Dingwang Technology (Wuhan) Co., Ltd. Contact Supplier

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54739-18-3 Fluvoxamine

CAS No.: 54739-18-3

Grade: Pharmaceutical Grade

Content: 99%

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HANGZHOU LEAP CHEM CO., LTD. Contact Supplier

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CAS No.: 54739-18-3

Content: 99.00%

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Shaanxi Kaierkai Pharmaceutical Technolo Contact Supplier

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Fluvoxamine KEK

CAS No.: 54739-18-3

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Guide of Fluvoxamine

Description
Basic Attributes
Characteristics
Use and Manufacturing
Drug Function and Efficacy
Related Drugs
Recommended Suppliers
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Fluvoxamine

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