Iron(2+) succinate
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Iron(2+) succinate
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CAS No:
10030-90-7
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Formula:
C4H6O4.Fe
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Chemical Name:
Iron(2+) succinate
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Synonyms:
Butanedioic acid,iron(2+) salt (1:1);Succinic acid,iron(2+) salt (1:1);Iron succinate (Fe(O4C4H4));Ferrous succinate;Ferrlecit 2;Iron succinate;Iron(2+) succinate;Cerevon;Ferromyn
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CAS No:
Iron(2+) succinate Basic Attributes
171.91716
171.94600
233-082-3
818ZYK7N91
B - Blood and blood forming organs
Toxicity
Acute iron overdosage can be divided into four stages. In the first stage, which occurs up to six hours after ingestion, the principal symptoms are vomiting and diarrhea. Other symptoms include hypotension, tachycardia and CNS depression ranging from lethargy to coma. The second phase may occur at 6-24 hours after ingestion and is characterized by a temporary remission. In the third phase, gastrointestinal symptoms recur accompanied by shock, metabolic acidosis, coma, hepatic necrosis and jaundice, hypoglycemia, renal failure and pulmonary edema. The fourth phase may occur several weeks after ingestion and is characterized by gastrointestinal obstruction and liver damage. In a young child, 75 milligrams per kilogram is considered extremely dangerous. A dose of 30 milligrams per kilogram can lead to symptoms of toxicity. Estimates of a lethal dosage range from 180 milligrams per kilogram and upwards. A peak serum iron concentration of five micrograms or more per ml is associated with moderate to severe poisoning in many.
Drug Information
Used in preventing and treating iron-deficiency anemia.
The major activity of supplemental iron is in the prevention and treatment of iron deficiency anemia. Iron has putative immune-enhancing, anticarcinogenic and cognition-enhancing activities.
Agents which improve the quality of the blood, increasing the hemoglobin level and the number of erythrocytes. They are used in the treatment of anemias. (See all compounds classified as Hematinics.)
The efficiency of absorption depends on the salt form, the amount administered, the dosing regimen and the size of iron stores. Subjects with normal iron stores absorb 10% to 35% of an iron dose. Those who are iron deficient may absorb up to 95% of an iron dose.
Iron is necessary for the production of hemoglobin. Iron-deficiency can lead to decreased production of hemoglobin and a microcytic, hypochromic anemia.
butanedioic acid, iron (+2) salt
Computed Properties
Molecular Weight:171.92
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:171.945894
Monoisotopic Mass:171.945894
Topological Polar Surface Area:80.3
Heavy Atom Count:9
Complexity:81.6
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
Drug Function and Efficacy
Iron is a component of hemoglobin in red blood cells. When iron is deficient, the amount of hemoglobin synthesized by red blood cells decreases, causing the red blood cells to become smaller and their oxygen-carrying capacity to decrease, resulting in iron-deficiency anemia. Oral administration of this product can supplement iron and correct iron-deficiency anemia.
Registered Holders
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Xuancheng Menovo Pharmaceutical Co., Ltd.
Active
China
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Lianyungang Guike Pharmaceutical Co., Ltd.
Active
China
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Hunan Jiudian HONGYANG Pharmaceutical Co., Ltd.
Active
China
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