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Eprosartan

Eprosartan structure

CAS No:
133040-01-4
Formula:
C23H24N2O4S
Chemical Name:
Eprosartan
Synonyms:
2-Thiophenepropanoic acid,α-[[2-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazol-5-yl]methylene]-,(αE)-;2-Thiophenepropanoic acid,α-[[2-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazol-5-yl]methylene]-,(E)-;(αE)-α-[[2-Butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazol-5-yl]methylene]-2-thiophenepropanoic acid;SKF 108566;SKB 108566;Eprosartan;(E)-2-Butyl-1-(p-carboxybenzyl)-α-2-thenylimidazole-5-acrylic acid;Teveten;Navixen
Categories:
Active Pharmaceutical Ingredients > Circulatory System Drugs

Description

Light-Yellow SolidChEBI: A member of the class of imidazoles and thiophenes that is an angiotensin II receptor antagonist used for the treatment of high blood pressure.Teveten was launched in Germany for the treatment of hypertension. There are several ways in which it has been prepared, the shortest of which is four steps; beginning with displacement of 2-butyl-4-chloroimidazole-5-carboxaldehyde with methyl 4-(bromomethyl)benzoate. Teveten is an angiotensin Ⅱ antagonist selective for th

Eprosartan Basic Attributes

Molecular Weight：

424.51

Exact Mass：

424.51

Characteristics

PSA：

121

XLogP3：

3.9

Appearance：

Solid

Density：

1.3±0.1 g/cm3

Melting Point：

260-261 °C

Boiling Point：

660.6±55.0 °C at 760 mmHg

Flash Point：

353.3±31.5 °C

Refractive Index：

1.628

Water Solubility：

H2O: Insoluble (mesylate form)

Storage Conditions：

-20°C Freezer

Vapor Pressure：

3.3X10-15 mm Hg at 25 deg C (est)

Safety Information

hazard class code：

R36/37/38

safety instructions：

S26

Marks：

Stability/Shelf Life：

Stable under recommended storage conditions.

Eprosartan Use and Manufacturing

Eprosartan is a prototype of the imidazoleacrylic acid angiotensin II receptor antagonists. Eprosartan is an antihypertensive.

Material

Methyl acrylate

Drug Function and Efficacy

Extract from the above information

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Eprosartan Tablets
Specifications	600 mg

Eprosartan Tablets
Specifications	600 mg

Eprosartan Tablets
Specifications	600mg

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Registered Holders

LONZA LTD

Marshall Island
Inactive