 Home > Encyclopedia > (-)-Oxyfedrine

(-)-Oxyfedrine

(-)-Oxyfedrine structure

CAS No:
15687-41-9
Formula:
C19H23NO3
Chemical Name:
(-)-Oxyfedrine
Synonyms:
1-Propanone,3-[[(1S,2R)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-(3-methoxyphenyl)-;1-Propanone,3-[(2-hydroxy-1-methyl-2-phenylethyl)amino]-1-(3-methoxyphenyl)-,[R-(R*,S*)]-;3-[[(1S,2R)-2-Hydroxy-1-methyl-2-phenylethyl]amino]-1-(3-methoxyphenyl)-1-propanone;L-3-[(β-Hydroxy-α-methylphenethyl)amino]-3′-methoxypropiophenone;Oxyfedrine;Oxyfedrin;Oxyphedrine;L-(1-Hydroxy-1-phenyl-2-propylamino)-1-(m-methoxyphenyl)-1-propanone;(-)-Oxyfedrine;22550-83-0
Categories:
Organic Chemistry > Amides

Description

Oxyfedrine is an aromatic ketone.|A drug used in the treatment of angina pectoris, heart failure, conduction defects, and myocardial infarction. It is a partial agonist at beta adrenergic receptors and acts as a coronary vasodilator and cardiotonic agent.

(-)-Oxyfedrine Basic Attributes

Molecular Weight：

313.39082

Exact Mass：

313.39

UNII：

DWL616XF1K

DSSTox ID：

DTXSID0023408

ATC Code：

C - Cardiovascular system

Characteristics

PSA：

58.6

XLogP3：

4.17260

Density：

1.122 g/cm3

Boiling Point：

475.2ºC at 760 mmHg

Flash Point：

241.2ºC

Refractive Index：

1.566

Vapor Pressure：

7.78E-10mmHg at 25°C

Drug Information

MeSH：

Drugs used to cause dilation of the blood vessels. (See all compounds classified as Vasodilator Agents.)|Drugs that selectively bind to and activate beta-adrenergic receptors. (See all compounds classified as Adrenergic beta-Agonists.)|Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE). (See all compounds classified as Cardiotonic Agents.)

MeSH Entry Terms：

Ildamen

(-)-Oxyfedrine Use and Manufacturing

Oxyfedrine acts as a vasodilator affecting the coronary base flow.

Computed Properties

Molecular Weight:313.4
XLogP3:2.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:8
Exact Mass:313.16779360
Monoisotopic Mass:313.16779360
Topological Polar Surface Area:58.6
Heavy Atom Count:23
Complexity:355
Defined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Material

Paraformaldehyde

Recommended Suppliers of (-)-Oxyfedrine

Shaanxi Dideu Medichem Co. Ltd Contact Supplier

CN
5 YRS

Business licensed Certified factory

Manufactory Supplier of Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst,Chemical Materials,Chem&Pharm Intermediates,Organic Intermediates,Feed Additive

Oxyfedrine 99%

CAS No.: 15687-41-9

Grade: Pharmaceutical Grade

Inquiry