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Tenofovir disoproxil

Tenofovir disoproxil structure

CAS No:
201341-05-1
Formula:
C19H30N5O10P
Chemical Name:
Tenofovir disoproxil
Synonyms:
2,4,6,8-Tetraoxa-5-phosphanonanedioic acid,5-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-,1,9-bis(1-methylethyl) ester,5-oxide;2,4,6,8-Tetraoxa-5-phosphanonanedioic acid,5-[[2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-,bis(1-methylethyl) ester,5-oxide,(R)-;2,4,6,8-Tetraoxa-5-phosphanonanedioic acid,5-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-,bis(1-methylethyl) ester,5-oxide;Bis-POC-PMPA;Tenofovir disoproxil;GS 4331
Categories:
Active Pharmaceutical Ingredients > Synthetic Anti-infective Drugs

Description

Tenofovir dsoproxil is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B.

Molecular Weight：

519.44

Exact Mass：

519.44

EC Number：

111-111-1

PSA：

185

XLogP3：

1.6

Density：

1.5±0.1 g/cm3

Melting Point：

276-280 °C

Boiling Point：

642.7°C at 760 mmHg

Flash Point：

342.5±34.3 °C

Refractive Index：

1.578

Water Solubility：

13.4 mg/mL in distilled water at 25 °C (disoproxil fumarate salt)

Storage Conditions：

-20°C

Vapor Pressure：

2.06E-16mmHg at 25°C

PKA：

3.75None

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