 Home > Encyclopedia > Cefsulodin sodium

Cefsulodin sodium

Cefsulodin sodium structure

CAS No:
52152-93-9
Formula:
C22H20N4O8S2.Na
Chemical Name:
Cefsulodin sodium
Synonyms:
Pyridinium,4-(aminocarbonyl)-1-[[(6R,7R)-2-carboxy-8-oxo-7-[[(2R)-2-phenyl-2-sulfoacetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-,inner salt,sodium salt (1:1);Pyridinium,4-(aminocarbonyl)-1-[[2-carboxy-8-oxo-7-[(phenylsulfoacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-,hydroxide,inner salt,monosodium salt,[6R-[6α,7β(R*)]]-;Pyridinium,4-(aminocarbonyl)-1-[[(6R,7R)-2-carboxy-8-oxo-7-[[(2R)-phenylsulfoacetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-,inner salt,monosodium salt;7-(D-α-Sulfophenylacetamido)ceph-3-em-3-(4′-carbamoylpyridinium)methyl-4-carboxylate sodium salt;SCE 129;Cefsulodin;Cefsulodin sodium;CGP 7174E;Monosodium cefsulodin;D-(-)-SCE-129;Takesulin;Tilmapor;Sodium cefsulodin;Pyridinium,4-(aminocarbonyl)-1-[[2-carboxy-8-oxo-7-[(phenylsulfoacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-,inner salt,monosodium salt,[6R-[6α,7β(R*)]]-;Pseudomonil;Sulcephalosporin;Abbot 46811;Cefomonil;Monaspor;Pyocefal;Ulfar;Pseudocef
Categories:
Active Pharmaceutical Ingredients > Synthetic Anti-infective Drugs

Description

Cefsulodin sodium salt hydrate is a third generation β lactam antibiotic and member of the cephems subgroub of antibiotics. Target: AntibacterialThe compound displays a mechanism of action like many β lactam antibiotics through inhibition of cell wall synthesis by competitively inhibiting penicillin binding protein (PBP) crosslinking of peptidoglycan resulting in inhibition of the final transpeptidation step. Through the inability for Cefsulodin sodium salt hydrate to inhibit cefsulodin-

Cefsulodin sodium Basic Attributes

Molecular Weight：

554.53

Exact Mass：

554.054199

EC Number：

257-692-4

DSSTox ID：

DTXSID6045585

HScode：

29419059

Characteristics

PSA：

227.39000

XLogP3：

-0.12670

Appearance：

White to pale yellow crystalline powder

Melting Point：

175 °C (decomp)

Water Solubility：

soluble in water.H2O: 50 mg/mL, clear, light yellow

Storage Conditions：

2-8°C

Toxicity：

Intravenous-rat LD50: 3030 mg/kg; Intravenous-mouse LD50: 3780 mg/kg

Flammability characteristics：

Thermal decomposition releases toxic nitrogen oxides, sulfur oxides, sodium oxide fumes

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

36/37/38-42/43-20/21/22

safety instructions：

22-26-36/37-45-36

RTECS Number：

UU1785000

Marks：

Xi,Xn

Storage features：

The warehouse is low-temperature, ventilated and dry

Precautionary statement(s)：

P261-P280-P305 + P351 + P338

Hazard Statements：

H315-H317-H319-H335

GHS Classification：

|Danger|H315 (96.08%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P272, P280, P285, P302+P352, P304+P340, P304+P341, P305+P351+P338, P312, P321, P332+P313, P333+P313, P337+P313, P342+P311, P362, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 51 companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Toxicity

Toxicity class：

practically nontoxic

Cefsulodin sodium Use and Manufacturing

Uses

A β lactam antibiotic.

Manufacturing Info：

Pyridinium, 4-(aminocarbonyl)-1-[[(6R,7R)-2-carboxy-8-oxo-7-[[(2R)-2-phenyl-2-sulfoacetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, inner salt, sodium salt (1:1): ACTIVE|PMN - indicates a commenced PMN (Pre-Manufacture Notices) substance.

Computed Properties

Molecular Weight:572.5
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:6
Exact Mass:572.06476489
Monoisotopic Mass:572.06476489
Topological Polar Surface Area:228
Heavy Atom Count:38
Complexity:1040
Defined Atom Stereocenter Count:3
Covalently-Bonded Unit Count:3
Compound Is Canonicalized:Yes

Recommended Suppliers of Cefsulodin sodium

Hangzhou Dawn Ray Pharmaceutical Co.,Ltd Contact Supplier

CN
5 YRS

Business licensed Certified factory

Manufactory Supplier of D-Biotin,Tobramycin base,L(-)-Carnitine base,Polymyxin B sulfate USP,Kanamycin sulfate monohydrate,Finasteride 99% USP

Cefsulodine sodium antibiocs pharmaceutical supplier Diminish inflammation

CAS No.: 52152-93-9

Inquiry
Shaanxi Dideu Medichem Co. Ltd Contact Supplier

CN
4 YRS

Business licensed Certified factory

Manufactory Supplier of Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst,Chemical Materials,Chem&Pharm Intermediates,Organic Intermediates,Feed Additive

cefsulodin sodium salt1KG

Unit Price: $10000 /Unit EXW

CAS No.: 52152-93-9

Grade: Industrial Grade

Inquiry