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Benzenemethanol, 2-chloro-α-[[(1-methylethyl)amino]methyl]-, hydrochloride (1:1)

Benzenemethanol, 2-chloro-α-[[(1-methylethyl)amino]methyl]-, hydrochloride (1:1) structure

CAS No:
6933-90-0
Formula:
C11H16ClNO.ClH
Chemical Name:
Benzenemethanol, 2-chloro-α-[[(1-methylethyl)amino]methyl]-, hydrochloride (1:1)
Synonyms:
Benzenemethanol,2-chloro-α-[[(1-methylethyl)amino]methyl]-,hydrochloride (1:1);Benzyl alcohol,o-chloro-α-[(isopropylamino)methyl]-,hydrochloride;Benzenemethanol,2-chloro-α-[[(1-methylethyl)amino]methyl]-,hydrochloride;Isoprophenamine hydrochloride;Clorprenaline hydrochloride;NSC 334693;N-[2-(2-Chlorophenyl)-2-hydroxyethyl]propan-2-aminium chloride;Chlorprenaline hydrochloride;1-(2-Chlorophenyl)-2-(isopropylamino)ethanol hydrochloride;14202-75-6
Categories:
Active Pharmaceutical Ingredients > Respiratory Drugs

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Description

Clorprenaline hydrochloride is a β2-adrenergic receptor agonist.

Benzenemethanol, 2-chloro-α-[[(1-methylethyl)amino]methyl]-, hydrochloride (1:1) Basic Attributes

Molecular Weight：

250.16

Exact Mass：

267.079285

EC Number：

230-058-4

NSC Number：

334693

DSSTox ID：

DTXSID5046699

HScode：

2922199090

Characteristics

PSA：

32.3

XLogP3：

3.56430

Melting Point：

165-169ºC

Boiling Point：

329.7ºC at 760 mmHg

Flash Point：

153.2ºC

Drug Information

MeSH：

Agents that cause an increase in the expansion of a bronchus or bronchial tubes. (See all compounds classified as Bronchodilator Agents.)|Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters. (See all compounds classified as Sympathomimetics.)

MeSH Entry Terms：

chlorprenaline

Benzenemethanol, 2-chloro-α-[[(1-methylethyl)amino]methyl]-, hydrochloride (1:1) Use and Manufacturing

Used to treat bronchial asthma

Computed Properties

Molecular Weight:250.16
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:249.0687196
Monoisotopic Mass:249.0687196
Topological Polar Surface Area:32.3
Heavy Atom Count:15
Complexity:163
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

Drug Function and Efficacy

Selective beta-2 receptor agonist, can relieve bronchial smooth muscle spasm

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Compound Chlorprenaline Houttuynia Sodium Tablets
Ingredients	Each tablet contains 4 mg of chlorprenaline hydrochloride, 4 mg of bromhexine hydrochloride, 20 mg of houttuynia cordata sodium, and 1.5 mg of chlorpheniramine maleate. The auxiliary materials are appropriate amounts of starch and dextrin.
Indication	1. Do not use with monoamine oxidase inhibitors (such as furazolidone, pargyline, etc.). 2. Do not use with other bronchodilator beta-2 receptor agonists. 3. Use with anticholinergics or theophylline drugs to enhance the effect of relieving asthma. 4. If used with other drugs at the same time, drug interactions may occur. Please consult a physician or pharmacist for details.
Specifications	Compound
Manufacturer	Jilin Xianfeng Technical Pharmaceutical Co., Ltd.

Compound chlorprenaline and bromhexine tablets
Ingredients	Chlorprenaline hydrochloride 5mg, bromhexine hydrochloride 10mg, deschlorohydroxyzine hydrochloride 25mg
Indication	1. It has an additive effect when used in combination with other bronchial β2 receptor agonists. 2. When this product is used in combination with other β2 receptor agonists, the efficacy is reduced and adverse reactions such as hand tremors and palpitations may be more obvious. 3. If used in combination with phosphodiesterase inhibitors such as theophylline or anticholinergic antiasthmatic drugs, its bronchial dilation and asthma relief effects are enhanced. 4. Bromhexine hydrochloride can increase the concentration of tetracycline antibiotics in the bronchi.
Specifications	Chlorprenaline hydrochloride 5mg, bromhexine hydrochloride 10mg, deschlorohydroxyzine hydrochloride 25mg
Manufacturer	Zhejiang Dongri Pharmaceutical Co., Ltd.

Compound chlorprenaline and bromhexine capsules
Ingredients	This product is a compound preparation, each tablet containing 5 mg of chlorprenaline hydrochloride, 10 mg of bromhexine hydrochloride, and 25 mg of deschlorohydroxyzine hydrochloride.
Indication	1. It has an additive effect when used in combination with other bronchial β2 receptor agonists. 2. When this product is used in combination with other bronchial β2 receptor agonists, the efficacy is reduced and adverse reactions such as hand tremors and palpitations may be more obvious. 3. If combined with phosphodiesterase inhibitors such as theophylline or anticholinergic antiasthmatic drugs, its effect of dilating the bronchi and relieving asthma is enhanced. 4. Bromhexine hydrochloride can increase the concentration of tetracycline antibiotics in the bronchi.
Specifications	Each tablet contains 5mg of chlorprenaline hydrochloride, 10mg of bromhexine hydrochloride, and 25mg of deschlorohydroxyzine hydrochloride
Manufacturer	Wanbangde Pharmaceutical Group Co., Ltd.

See More Related Drugs

Registered Holders

Wanbangde Pharmaceutical Group Co., Ltd.

China
Active
Taicang Pharmaceutical FACTORY

China
Active

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CAS No.: 6933-90-0

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Content: 99%

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Pharmaceutical API 99% Clorprenaline hydrochloride powder CAS 6933-90-0 Factory Supply

CAS No.: 6933-90-0

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Clorprenaline hydrochloride cas 6933-90-0

CAS No.: 6933-90-0

Grade: Analytical Reagent

Content: 99%

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Guide of Benzenemethanol, 2-chloro-α-[[(1-methylethyl)amino]methyl]-, hydrochloride (1:1)

Description
Basic Attributes
Characteristics
Drug Information
Use and Manufacturing
Computed Properties
Drug Function and Efficacy
Related Drugs
Registered Holders
Recommended Suppliers
Latest News
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Benzenemethanol, 2-chloro-α-[[(1-methylethyl)amino]methyl]-, hydrochloride (1:1)

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