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Taxifolin

Taxifolin structure

CAS No:
480-18-2
Formula:
C15H12O7
Chemical Name:
Taxifolin
Synonyms:
4H-1-Benzopyran-4-one,2-(3,4-dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-,(2R,3R)-;4H-1-Benzopyran-4-one,2-(3,4-dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-,(2R-trans)-;Flavanone,3,3′,4′,5,7-pentahydroxy-;(2R,3R)-2-(3,4-Dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one;Distylin;Taxifolin;Taxifoliol;Dihydroquercetin;(+)-Taxifolin;(+)-Dihydroquercetin;(2R,3R)-Dihydroquercetin;2,3-Dihydroquercetin;3,5,7,3′,4′-Pentahydroxyflavanone;Diquertin;(2R,3R)-(+)-Taxifolin;Lariksin;Lavitol;(+)-trans-Taxifolin;(2R,3R)-3,3′,4′,5,7-Pentahydroxyflavanone;Flamena D;(+)-(2R,3R)-Dihydroquercetin;Flamena;Jikuberuchin;Flavomix;98006-93-0;5117-01-1;5323-70-6;17654-26-1;20254-28-8;24198-96-7;28929-10-4
Categories:
Cosmetic Ingredient > Antioxidant Ingredient

Description

Taxifolin exhibits important anti-tyrosinase activity. Taxifolin exhibits significant inhibitory activity against collagenase with an IC50 value of 193.3 μM.

(+)-taxifolin is a taxifolin that has (2R,3R)-configuration. It has a role as a metabolite. It is a conjugate acid of a (+)-taxifolin(1-). It is an enantiomer of a (-)-taxifolin.

Taxifolin Basic Attributes

Molecular Weight：

304.25

Exact Mass：

304.25

EC Number：

207-543-4

UNII：

9SOB9E3987

DSSTox ID：

DTXSID8022450

HScode：

2932999099

Characteristics

PSA：

127

XLogP3：

1.5

Appearance：

Yellowish powder

Density：

1.7±0.1 g/cm3

Melting Point：

0.237 °C (approx)

Boiling Point：

687.6°C at 760 mmHg

Flash Point：

264.2±25.0 °C

Refractive Index：

1.763

Storage Conditions：

-20°C Freezer

Vapor Pressure：

7.51E-20mmHg at 25°C

Safety Information

Hazard category：

IRRITANT

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

safety instructions：

22-24/25

RTECS Number：

LK6920000

Precautionary statement(s)：

P264, P270, P301+P312, P330, P501

Hazard Statements：

H302

Drug Information

MeSH：

Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions.They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)

MeSH Entry Terms：

dihydroquercetin

Taxifolin Use and Manufacturing

Uses

An antioxidant flavenoid.

Manufacturing Info：

4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-, (2R,3R)-: ACTIVE

Computed Properties

Molecular Weight:304.25
XLogP3:1.5
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:1
Exact Mass:304.05830272
Monoisotopic Mass:304.05830272
Topological Polar Surface Area:127
Heavy Atom Count:22
Complexity:428
Defined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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taxifolin (dihydroquercetin)

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Learn More Other Chemicals

Taxifolin 3-acetate

78834-97-6
Taxifolin 3′-O-β-D-glucopyranoside

31106-05-5
Taxifolin 3-O-beta-D-xylopyraside

40672-47-7
Dilauryl thiodipropionate Formula

123-28-4
5-Hydroxy-2-[(1S)-1-hydroxyethyl]naphtho[2,3-b]furan-4,9-dione Formula

123297-90-5
Hydroquinone Formula

123-31-9
trans-Crotonaldehyde Structure

123-73-9
Crotonaldehyde Structure

4170-30-3
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123-93-3
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124-20-9

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Guide of Taxifolin

Description
Basic Attributes
Characteristics
Safety Information
Drug Information
Use and Manufacturing
Computed Properties
Recommended Suppliers
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Taxifolin

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