Taxifolin
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Taxifolin
structure -
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CAS No:
480-18-2
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Formula:
C15H12O7
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Chemical Name:
Taxifolin
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Synonyms:
4H-1-Benzopyran-4-one,2-(3,4-dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-,(2R,3R)-;4H-1-Benzopyran-4-one,2-(3,4-dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-,(2R-trans)-;Flavanone,3,3′,4′,5,7-pentahydroxy-;(2R,3R)-2-(3,4-Dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one;Distylin;Taxifolin;Taxifoliol;Dihydroquercetin;(+)-Taxifolin;(+)-Dihydroquercetin;(2R,3R)-Dihydroquercetin;2,3-Dihydroquercetin;3,5,7,3′,4′-Pentahydroxyflavanone;Diquertin;(2R,3R)-(+)-Taxifolin;Lariksin;Lavitol;(+)-trans-Taxifolin;(2R,3R)-3,3′,4′,5,7-Pentahydroxyflavanone;Flamena D;(+)-(2R,3R)-Dihydroquercetin;Flamena;Jikuberuchin;Flavomix;98006-93-0;5117-01-1;5323-70-6;17654-26-1;20254-28-8;24198-96-7;28929-10-4
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CAS No:
Description
Taxifolin exhibits important anti-tyrosinase activity. Taxifolin exhibits significant inhibitory activity against collagenase with an IC50 value of 193.3 μM.
(+)-taxifolin is a taxifolin that has (2R,3R)-configuration. It has a role as a metabolite. It is a conjugate acid of a (+)-taxifolin(1-). It is an enantiomer of a (-)-taxifolin.
Characteristics
127
1.5
Yellowish powder
1.7±0.1 g/cm3
0.237 °C (approx)
687.6°C at 760 mmHg
264.2±25.0 °C
1.763
-20°C Freezer
7.51E-20mmHg at 25°C
Safety Information
IRRITANT
NONH for all modes of transport
3
22
22-24/25
LK6920000
P264, P270, P301+P312, P330, P501
H302
Drug Information
Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions.They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)
dihydroquercetin
Taxifolin Use and Manufacturing
An antioxidant flavenoid.
4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-, (2R,3R)-: ACTIVE
Computed Properties
Molecular Weight:304.25
XLogP3:1.5
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:1
Exact Mass:304.05830272
Monoisotopic Mass:304.05830272
Topological Polar Surface Area:127
Heavy Atom Count:22
Complexity:428
Defined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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