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Lasalocid sodium

Lasalocid sodium structure

CAS No:
25999-20-6
Formula:
C34H54O8.Na
Chemical Name:
Lasalocid sodium
Synonyms:
Benzoic acid,6-[(3R,4S,5S,7R)-7-[(2S,3S,5S)-5-ethyl-5-[(2R,5R,6S)-5-ethyltetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl]tetrahydro-3-methyl-2-furanyl]-4-hydroxy-3,5-dimethyl-6-oxononyl]-2-hydroxy-3-methyl-,sodium salt (1:1);2,3-Cresotic acid,6-[7-[5-ethyl-5-(5-ethyltetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)tetrahydro-3-methyl-2-furyl]-4-hydroxy-3,5-dimethyl-6-oxononyl]-,monosodium salt,(-)-;Benzoic acid,6-[7-[5-ethyl-5-(5-ethyltetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)tetrahydro-3-methyl-2-furanyl]-4-hydroxy-3,5-dimethyl-6-oxononyl]-2-hydroxy-3-methyl-,monosodium salt,[2R-[2α[2S*(3R*,4S*,5S*,7R*),3S*,5S*],5α,6β]]-;Benzoic acid,6-[(3R,4S,5S,7R)-7-[(2S,3S,5S)-5-ethyl-5-[(2R,5R,6S)-5-ethyltetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl]tetrahydro-3-methyl-2-furanyl]-4-hydroxy-3,5-dimethyl-6-oxononyl]-2-hydroxy-3-methyl-,monosodium salt;Lasalocid sodium;Ro 2-2985;Sodium lasalocid A;Avatec;Sodium lasalocid;Lasalocid sodium salt;Bovatec;MT 2007;NSC 243046;33913-39-2;57157-99-0;67249-45-0;73837-09-9
Categories:
Active Pharmaceutical Ingredients > Antiparasitic Drugs

Description

In vitro: Lasalocid sodium treatment led to an increase in cell wall thickness, whilst the quantity and sugar composition of the cell wall remained unchanged in BY-2 cells. Lasalocid sodium treatment enhances enzymatic saccharification efficiency in both BY-2 cells and Arabidopsis plants. [1]

Lasalocid sodium Basic Attributes

Molecular Weight：

612.77

Exact Mass：

612.36400

EC Number：

247-400-3

Characteristics

PSA：

136.35000

XLogP3：

4.50750

Density：

1.119g/cm3

Melting Point：

168-171 °C

Boiling Point：

735.7ºC at 760mmHg

Flash Point：

6 °C

Refractive Index：

1.528

Storage Conditions：

0-6°C

Safety Information

Packing level：

III

Hazard category：

6.1(b)

Transport codes：

2811

hazard class code：

25-36-20/21/22-11

safety instructions：

28-45-36/37-16

RTECS Number：

GP4180000

Marks：

T,Xn,F

Lasalocid sodium Use and Manufacturing

Methods of Manufacturing

It is produced by fermentation of Streptomyces lasaliensis.

Uses

Lasalocid sodium is a salt of the polyether ionophore lasalocid, with potent antibacterial activity. Lasalocid was developed as an animal health product for treatment of coccidia. Lasalocid is able to form neutral complexes with monovalent and divalent cations and transport the ions through apolar phase, including lipid bilayer membranes. Interestingly, lasalocid can also transport larger organic cations, e.g. protonated dopamine.

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