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LINCOMYCIN HYDROCHLORIDE

LINCOMYCIN HYDROCHLORIDE structure

CAS No:
17017-22-0
Formula:
C18H34N2O6S
Chemical Name:
LINCOMYCIN HYDROCHLORIDE
Synonyms:
METHYL 6,8-DIDEOXY-6-(1-METHYL-4-PROPYL-2-PYRROLIDINECARBOXAMIDO)-1-THIO-D-ERYTHRO-ALPHA-D-GALACTOOCTOPYRANOSIDE HYDROCHLORIDE;LINCOCIN HYDROCHLORIDE;N-[2-HYDROXY-1-(3,4,5-TRIHYDROXY-6-METHYLSULFANYL-OXAN-2-YL)-PROPYL]-1-METHYL-4-PROPYL-PYRROLIDINE-2-CARBOXAMIDE;U-10149A;lincomyicin,;7-Epi LincoMycin;ALPHA-METHYL-6,8-DIDEOXY-6-[1-METHYL-4-PROPYL-2-PYRROLIDINECARBOXAMIDO]-1-THIO-D-ERYTHRO-D-GALACTOOCTOPYRANOSIDE HYDROCHLORIDE;(7S)-Lincomycin
Categories:
Active Pharmaceutical Ingredients > Antibiotics

Description

An antibiotic produced by Streptomyces lincolnensis var. lincolnensis. It has been used in the treatment of staphylococcal, streptococcal, and Bacteroides fragilis infections.

LINCOMYCIN HYDROCHLORIDE Basic Attributes

Molecular Weight：

406.54

Exact Mass：

406.21400

EC Number：

212-726-7

Characteristics

PSA：

147.79000

XLogP3：

0.2

Density：

1.29

Boiling Point：

646.8±55.0 °C(Predicted)

Water Solubility：

H2O: 50 mg/mL, clear, colorless

Storage Conditions：

2-8°C

PKA：

12.91±0.70(Predicted)

Critical Temperature & Pressure：

2-8°C

Safety Information

wgk germany：

hazard class code：

safety instructions：

RTECS Number：

RH6315000

Marks：

Hazard Statements：

36/37/38

Drug Information

MeSH：

Compounds which inhibit the synthesis of proteins. They are usually ANTI-BACTERIAL AGENTS or toxins. Mechanism of the action of inhibition includes the interruption of peptide-chain elongation, the blocking the A site of ribosomes, the misreading of the genetic code or the prevention of the attachment of oligosaccharide side chains to glycoproteins. (See all compounds classified as Protein Synthesis Inhibitors.)|Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)

MeSH Entry Terms：

Epilincomycin

LINCOMYCIN HYDROCHLORIDE Use and Manufacturing

Uses

An epimer of Lincomycin (L466200); a 6-amino, 6-deoxy-octopyraninose with strong antibiotic activity. A less potent bactericidal than its (7R)-epimer.

Use Classification：

Human Drugs -> FDA Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book) -> Active Ingredients

Computed Properties

Molecular Weight:406.5
XLogP3:0.2
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:7
Exact Mass:406.21375798
Monoisotopic Mass:406.21375798
Topological Polar Surface Area:148
Heavy Atom Count:27
Complexity:499
Undefined Atom Stereocenter Count:9
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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CAS No.: 17017-22-0

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Lincomycin HCL 17017-22-0

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CAS No.: 17017-22-0

Grade: Chemical Grade

Content: 99%

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