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Menotropin

Menotropin structure

CAS No:
61489-71-2
Chemical Name:
Menotropin
Synonyms:
Gonadotropin,menopausal;Menopausal gonadotropin;Pergonal;Humegon;Human menopausal gonadotropin;Menotropin;Neopergonal;Homogonal;Pergovet;Normegon;Menotrophin;Humegon 100;Pergonal 75;Pergonal 150;Lepori;Menogon;Merional;Repronex;Menopur;Human menopausal gonadotrophin;Urogonadotropin;hMG Fuji;Ovugraf HP;Menogon HP;Menotropins
Categories:
Active Pharmaceutical Ingredients > Antibiotics

Description

Extracts of urine from menopausal women that contain high concentrations of pituitary gonadotropins, FOLLICLE STIMULATING HORMONE and LUTEINIZING HORMONE. Menotropins are used to treat infertility. The FSH:LH ratio and degree of purity vary in different preparations.

Menotropin Basic Attributes

Molecular Weight：

142.23862

Exact Mass：

142.13600

EC Number：

612-157-8

ATC Code：

G - Genito urinary system and sex hormones

Characteristics

PSA：

17.07000

XLogP3：

2.79180

Water Solubility：

SOL IN WATER, PHYSIOLOGICAL SALINE SOLN, 50% ALC, IN PH 4.4 ACETATE BUFFER OF 20.5% SODIUM SULFATE

Storage Conditions：

2-8°C

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

RTECS Number：

MT6425640

Marks：

Stability/Shelf Life：

IN 50% ALC SOLN ACTIVITY IS DESTROYED @ 60 DEG C WITHIN 15 MIN

Drug Information

Drug Indication：

Treatment of female infertility

MeSH：

Compounds which increase the capacity to conceive in females. (See all compounds classified as Fertility Agents, Female.)

MeSH Entry Terms：

CP 89044

Menotropin Use and Manufacturing

Methods of Manufacturing

Urine of menopausal women is extracted, refined, and depyrogenated.

Uses

For biochemical and clinical medical research, for the treatment of infertility.

Use Classification：

Human Drugs -> EU pediatric investigation plans

Computed Properties

Molecular Weight:142.24
XLogP3:3
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:5
Exact Mass:142.135765193
Monoisotopic Mass:142.135765193
Topological Polar Surface Area:17.1
Heavy Atom Count:10
Complexity:89.4
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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