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Cefotiam hydrochloride

Cefotiam hydrochloride structure

CAS No:
66309-69-1
Formula:
C18H23N9O4S3.2ClH
Chemical Name:
Cefotiam hydrochloride
Synonyms:
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[2-(2-amino-4-thiazolyl)acetyl]amino]-3-[[[1-[2-(dimethylamino)ethyl]-1H-tetrazol-5-yl]thio]methyl]-8-oxo-,hydrochloride (1:2),(6R,7R)-;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2-amino-4-thiazolyl)acetyl]amino]-3-[[[1-[2-(dimethylamino)ethyl]-1H-tetrazol-5-yl]thio]methyl]-8-oxo-,dihydrochloride,(6R-trans)-;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2-amino-4-thiazolyl)acetyl]amino]-3-[[[1-[2-(dimethylamino)ethyl]-1H-tetrazol-5-yl]thio]methyl]-8-oxo-,dihydrochloride,(6R,7R)-;Cefotiam hydrochloride;Halospor;Pansporin;Cefotiam dihydrochloride;Pansporine;Sporidyn;Abbott 48999;Spizef;HAR;KMS;SFP;SFC;PAS;HNP;SEP;Ceradon
Categories:
Active Pharmaceutical Ingredients > Antibiotics

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Description

Cefotiam hydrochloride Basic Attributes

Molecular Weight：

562.08

Exact Mass：

597.056885

EC Number：

266-312-6

HScode：

2941906000

Characteristics

PSA：

251.30000

XLogP3：

1.05880

Appearance：

white to tan

Boiling Point：

94℃

Flash Point：

>110°(230°F)

Water Solubility：

soluble in water

Storage Conditions：

Hygroscopic, -20°C Freezer, Under Inert Atmosphere

Toxicity：

Intravenous-rat LD50: 3680 mg/kg; Intravenous-mouse LD50: 3840 mg/kg

Flammability characteristics：

Thermal decomposition releases toxic nitrogen oxides, sulfur oxides, hydrogen chloride fumes

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

safety instructions：

RTECS Number：

XI0367000

Marks：

Storage features：

The warehouse is low-temperature, ventilated and dry

Precautionary statement(s)：

P261-P280-P284-P304 + P340-P342 + P311

Hazard Statements：

H317-H334

Toxicity

Toxicity class：

practically nontoxic

Cefotiam hydrochloride Use and Manufacturing

Cephalosporin Antibiotic.

Price Analysis

Make your Cefotiam hydrochloride purchase based on the price and market insights! ECHEMI provides professional market insights with prices for you to make a better choice. Learn more on Cefotiam hydrochloride prices .

Drug Function and Efficacy

No specific description of pharmacological action is provided

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Ceftiofiocin Hydrochloride
Manufacturer	Fuan Pharmaceutical Group Chongqing BOSEN Pharmaceutical Co., Ltd.

Ceftiofiorin Hydrochloride for Injection
Ingredients	The main ingredient of this product is ceftriaxone hydrochloride, and its chemical name is (6R-trans)-7-[[(2-amino-4-thiazolyl)acetyl]amino]-3-[[[1-[(2-(dimethylamino)ethyl]-1H-tetrazol-5-yl]thiomethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid dihydrochloride.
Indication	1. When used in combination with aminoglycoside antibiotics, it is generally believed to have a synergistic effect, but it may aggravate renal damage. Administering them in the same container may affect the potency of the drug. 2. When used in combination with strong diuretics such as furosemide, it may cause renal damage.
Specifications	0.5g (calculated as C18H23N9O4S3)
Manufacturer	Zhejiang Yongning Pharmaceutical Co., Ltd.

Ceftiofiorin Hydrochloride for Injection
Ingredients	The main ingredient of this product is ceftriaxone hydrochloride, and its chemical name is (6R-trans)-7-[[(2-amino-4-thiazolyl)acetyl]amino]-3-[[[1-[(2-(dimethylamino)ethyl]-1H-tetrazol-5-yl]thiomethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid dihydrochloride.
Indication	1. When used in combination with aminoglycoside antibiotics, it is generally believed to have a synergistic effect, but it may aggravate renal damage. Administering them in the same container may affect the potency of the drug. 2. When used in combination with strong diuretics such as furosemide, it may cause renal damage.
Specifications	2.0g (calculated based on 3 pieces of C18H23N9O4)
Manufacturer	Hainan Quanxing Pharmaceutical Co., Ltd.

See More Related Drugs

Registered Holders

Qingsong Pharmaceutical Group Co., Ltd.

China
Active
Amicogen(China) Biopharm Co., Ltd.

China
Active
China UNION Chempharma (SUZHOU) Co., Ltd.

China
Active

See More Registered Holders

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